DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31262 and SPBPB8B6.02c

DIOPT Version :9

Sequence 1:	NP_001138069.2	Gene:	CG31262 / 318649	FlyBaseID:	FBgn0051262	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001018763.1	Gene:	SPBPB8B6.02c / 3361185	PomBaseID:	SPBPB8B6.02c	Length:	673	Species:	Schizosaccharomyces pombe

Alignment Length:	495	Identity:	120/495 - (24%)
Similarity:	196/495 - (39%)	Gaps:	126/495 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 AIILQGIAFSYVY-------LPVYSALQIGSAYEYLGLRFNS---IIRTTASFMYV-FGILTYLP 153
            |.:|...|:||.|       ..|...:|| :.:.:|.::...   ...|.:...:: ||.|.:..
pombe    69 ATLLSSGAWSYTYGIMGGFMYGVGGTIQI-TLFLFLAIQIKKKAPAAHTVSECFFIRFGKLGHCV 132

  Fly   154 FIVY-------VPALSL-------SQVSGLNTHLIGLVIILACVTYTFMGGLKAVVHTDVWQVAV 204
            ::.|       |.:|.|       |..:|:||.....::.|..:.||.:|||||...:| |...|
pombe   133 YLFYCISTNVLVSSLLLLGGSQGFSSTTGMNTVAACFLLPLGVMVYTTLGGLKATFISD-WIHTV 196

  Fly   205 MFLSLVAVAFLAIYYSNGLVA----VFDDAEQ--------GGRLMLANTNPSPYVRHTVWSVLIG 257
            |...::.|....:|.|:.|:.    ::|..::        ||:..|:..|..  :.:..|||:||
pombe   197 MIYIILIVTCYTVYCSSSLIGSPAKMYDMLKEVQEVYPATGGQSYLSFKNSE--MMYLTWSVMIG 259

  Fly   258 GFSFWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKYKDCDPRSA 322
            |.|   || .|.....||  ::.|..||....::..       .||.::..:....       ||
pombe   260 GLS---SV-FGDPGYSQR--AIASDAKSVFQGYLMG-------GLCWWIIPMALGS-------SA 304

  Fly   323 G-----MILNDDQLLPLFVVQSVGHIYGMPGLF-IAGIFG-----AGL--------SSLSSCFNT 368
            |     ::||...:....|:.||....|:|.:: :|.|||     |||        |:.|:....
pombe   305 GLACRALLLNPASVTYPNVLSSVEISSGLPVIYGMASIFGKSGAAAGLVMLFMSITSATSAELIA 369

  Fly   369 VSMVFLEDIVRGFFKMEPSERQSTILIKTCIIFQGILAFLIVFLLQHLRGILSVCNSISSITAG- 432
            .|.|...||.|.:.....:.:|   |::|..:  .::.|.:..      |.|||..:.:.:|||
pombe   370 FSSVTTYDIFRAYINPAANGKQ---LVRTAHL--SVIGFSLFI------GALSVGFNYAGVTAGW 423

  Fly   433 --TSFGVF--------TLGMLF----PWANTIGTAVGGLSSVL--LAGWISFGSQIAAASGQLKS 481
              |..|:.        ||.:.:    .::..:|...|.::.|:  ||...||...|......:.|
pombe   424 LLTFLGIILTPEVSAVTLCLFWNKMTRFSLVVGAPFGTITGVVCWLASTYSFCDGIVNKDTVMTS 488

  Fly   482 GMLPVSVKEC-VGNVTLPEDPWVDQDQVFPLY--RLSYHW 518
                   |.| |||:......        |||  .|||.|
pombe   489 -------KACFVGNIVSMASS--------PLYIVLLSYIW 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	120/495 (24%)
SPBPB8B6.02c	NP_001018763.1	SLC5sbd_DUR3	11..513	CDD:271370	119/493 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	74	1.000	Domainoid score	I2508
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	80	1.000	Inparanoid score	I1855
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
TreeFam	0	0.000	Not matched by this tool.
	4	3.950