DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31262 and CG32669

DIOPT Version :9

Sequence 1:	NP_001138069.2	Gene:	CG31262 / 318649	FlyBaseID:	FBgn0051262	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_727460.1	Gene:	CG32669 / 326229	FlyBaseID:	FBgn0052669	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	587	Identity:	181/587 - (30%)
Similarity:	297/587 - (50%)	Gaps:	60/587 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPVS 71
            |..||.:|..:.::|...|||:..:..|...                 ..|||:..|:|.|.||:
  Fly     5 GAWDYTILAVVLIISVAIGIYYRFVGGKQST-----------------TTEYLLADRSMNVAPVA 52

  Fly    72 ITL----YRVTSIIGTPSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEYLGLRF 132
            .:|    ....:|:|...|.|.|||.:.:|.::.:|.....:|:.:||:..|:..|.||||.|||
  Fly    53 FSLMASFMSAVTILGVSMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRF 117

  Fly   133 NSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVII-LACVTYTFMGGLKAVVH 196
            ....|..||..:...::.|:..:||.|||:|..|:|| :.:..:||: :.|..|..:||:|||:.
  Fly   118 GYATRLAASLSFSLQMVLYMGIVVYAPALALEAVTGL-SQVFSIVIVGVVCTFYATLGGMKAVLI 181

  Fly   197 TDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTNPSPYVRHTVWSVLIGGFSF 261
            ||::|..:||.::.:|...|...:..|..::..|::.||:.|.|.:..|..|||.::.::||.:.
  Fly   182 TDIYQSLLMFAAVFSVIICAWVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCAT 246

  Fly   262 WTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIAL-CCFMGLLLFSKYKDCDPRSAGMI 325
            :.::....|..|||.|::.||..:| |:..:.:.:...::| .||.||.::..|:||||...|.:
  Fly   247 YLAIYGVNQTQVQRLMAVKSLSAAR-AALWWCLPILCLLSLSTCFSGLCIYWYYRDCDPLLEGRV 310

  Fly   326 LNDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFF----KMEP 386
            .:.||::|||||.::|...|:.|||::|||.|.||::||..::::.|.|||.::...    |...
  Fly   311 NSRDQVMPLFVVDTMGEYTGLAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTL 375

  Fly   387 SERQSTILIKTCIIFQGILAFLIVFLLQHLRGILSVCNSISSITAGTSFGVFTLGMLFPWANTIG 451
            ::||:....|...:|.|.|...:.|:...:.|:|....||..|..|...|:|||||....||..|
  Fly   376 TDRQTLWYSKLLSLFFGALCIGMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKG 440

  Fly   452 TAVGG-LSSVLLAGWISFGSQIAAASGQLKSGM--LPVSVKECVGNVTLPEDPWV-------DQD 506
             |:|| |.|:....||.|        ||.|..:  |.:|...|..:.:...|.::       :::
  Fly   441 -AIGGLLISLAFCFWIGF--------GQPKPPLVSLDMSTAGCPVDRSFARDIFLKTVIAVAEEE 496

  Fly   507 QVFPLYRLSYHWVSPIGVVTAVVVGALVS------------LITKPADIKTLHAELISPVIHRFL 559
            ..|.|||:||.|.:.:|.:.....|.|:|            .|.:.||...:..:|..|.|.:.|
  Fly   497 HYFYLYRISYMWYAALGFLITFFGGWLLSWLFALLKWDNNRRIYQDADCTLIKHDLFVPPIAKRL 561

  Fly   560 PR 561
            .|
  Fly   562 QR 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	168/532 (32%)
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	172/547 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45448270
Domainoid	1	1.000	97	1.000	Domainoid score	I370
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900