Protein Alignment CG31262 and Slc5a1

DIOPT Version :10

• Sequence 1: NP_732222.2
• Gene: CG31262 / 318649
• FlyBaseID: FBgn0051262
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_037165.1
• Gene: Slc5a1 / 25552
• RGDID: 3713
• Length: 665
• Species: Rattus norvegicus
• Alignment Length: 633
• Identity: 126/633 - (19%)
• Similarity: 234/633 - (36%)
• Gaps: 154/633 - (24%)

  Fly     9 VDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPVSIT 73
            :..:|:..:.:::.|....|.                  ||.|:  :..:.:..|:|...|:..:
  Rat    29 ISVIVIYFVVVMAVGLWAMFS------------------TNRGT--VGGFFLAGRSMVWWPIGAS 73

  Fly    74 LY-------RVTSIIGT--PSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEYL- 128
            |:       ....:.||  .:.|...|.::..::..::|     .::::|:|....:.:..|||
  Rat    74 LFASNIGSGHFVGLAGTGAAAGIAMGGFEWNALVFVVVL-----GWLFVPIYIKAGVVTMPEYLR 133

  Fly   129 ----GLRFNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYTFMG 189
                |.|....:...:..:|:|   |.:...::..|:.::...||:.:|...:::.....||..|
  Rat   134 KRFGGKRIQIYLSVLSLLLYIF---TKISADIFSGAIFINLALGLDIYLAIFILLAITALYTITG 195

  Fly   190 GLKAVVHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTN------------ 242
            ||.||::||..|.|:|.:....:...|.....|..|..|...:....::::.|
  Rat   196 GLAAVIYTDTLQTAIMLVGSFILTGFAFREVGGYEAFMDKYMKAIPTLVSDGNITVKEECYTPRA 260

  Fly   243 ------PSPYVRHTVWSVLIGGFS-----FWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGV 296
                  ..|......|..||.|.|     :|.:    .|.:|||.:|..::..           |
  Rat   261 DSFHIFRDPITGDMPWPGLIFGLSILALWYWCT----DQVIVQRCLSAKNMSH-----------V 310

  Fly   297 SIFIALCCFMGLL-LFSKYKDCDPRSAGMILNDDQL----------------------LPLFVVQ 338
            .....||.::.|| :|....   |.....||..|::                      .|..||:
  Rat   311 KAGCTLCGYLKLLPMFLMVM---PGMISRILYTDKIACVLPSECKKYCGTPVGCTNIAYPTLVVE 372

  Fly   339 SVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEPSERQSTILIKTCIIFQG 403
            .:.:  |:.||.::.:..:.:|||:|.||:.|.:|..||   :.|:.....:..::|...:....
  Rat   373 LMPN--GLRGLMLSVMMASLMSSLTSIFNSASTLFTMDI---YTKIRKGASEKELMIAGRLFILV 432

  Fly   404 ILAFLIVF--LLQHLRG--ILSVCNSISSITAGTSFGVFTLGMLFPWANTIGTAVGGLSSVLLAG 464
            ::...|.:  ::|..:.  :.....||:|........||.|.:.....|..| |..||....|.|
  Rat   433 LIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFCKRVNEPG-AFWGLILGFLIG 496

  Fly   465 WISFGSQIAAASGQLKSGMLPVSVKECVGNVTLPEDPWVDQDQVFPLYRLSYHWVSPIGVVTAVV 529
            .....::.|..:|   |.|.|.:..:.:..|                   .|.:.:.|....:||
  Rat   497 ISRMITEFAYGTG---SCMEPSNCPKIICGV-------------------HYLYFAIILFAISVV 539

  Fly   530 VGALVSLITKPADIKTLHAELISPVIHRFLPRECFRGRNLNERTEESL 577
            ...::||:|||.           |.:|  |.|.|:..||   .|||.:
  Rat   540 TVLVISLLTKPI-----------PDVH--LYRLCWSLRN---STEERI 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31262	NP_732222.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	108/576 (19%)
Slc5a1	NP_037165.1	SLC5-6-like_sbd	27..665	CDD:444915	126/633 (20%)