Protein Alignment CG31262 and Slc5a12

DIOPT Version :10

• Sequence 1: NP_732222.2
• Gene: CG31262 / 318649
• FlyBaseID: FBgn0051262
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001003915.1
• Gene: Slc5a12 / 241612
• MGIID: 2138890
• Length: 623
• Species: Mus musculus
• Alignment Length: 577
• Identity: 182/577 - (31%)
• Similarity: 297/577 - (51%)
• Gaps: 48/577 - (8%)

  Fly     6 FGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPV 70
            |...||:|...:.::|:|.|::| |:|::   ||:.|.             |:|:|.|.|...||
Mouse     6 FEAWDYVVFAGLFVISSGIGVFF-AIKER---KKTTSR-------------EFLVGGRQMSFGPV 53

  Fly    71 SITL----YRVTSIIGTPSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEYLGLR 131
            :::|    ....:::|||:|:|.:|..::|.:::.:......|.::|||:....|.|.||||.||
Mouse    54 ALSLTASFMSAVTVLGTPAEVYRFGASFFLFLISYVFVVFFTSELFLPVFYRSGITSTYEYLQLR 118

  Fly   132 FNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYTFMGGLKAVVH 196
            ||..:|..|:.:|:...:.|...:||.|||:|:||:|.|.........:.|..|..:|||||||.
Mouse   119 FNKPVRYAATIIYIVQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVW 183

  Fly   197 TDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTNPSPYVRHTVWSVLIGGFSF 261
            ||.:|:.||.:..:.|......:..|...|.:.|..|.||.:.:.:..|..|||.|::.|||...
Mouse   184 TDAFQMVVMIVGFLTVLIQGSNHVGGFNNVLEKAGNGSRLHIVDFDVDPLRRHTFWTITIGGTFT 248

  Fly   262 WTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKYKDCDPRSAGMIL 326
            |..|....|..:||.:|..:.|.::.|.:...:|:.|.:|...|.||:::|.:|||||.::|:|.
Mouse   249 WLGVYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIIVACAVFSGLIMYSHFKDCDPWTSGVIS 313

  Fly   327 NDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEPSERQS 391
            ..|||:|.||::....:.|:||||:|..|...||::::..|.::.|..||.|:..|. ..|::.|
Mouse   314 APDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFP-HLSDKLS 377

  Fly   392 TILIK-TCIIF------QGILAFLIVFLLQHLRGILS----VCNSISSITAGTSFGVFTLGMLFP 445
            |.:.| .||:|      ..::|.|:..::| ..||:|    :..|.....|...:||..
Mouse   378 TWISKGLCILFGIMCTSMAVVASLMGSVVQ-APGIVSQERAITGSFQRNLASVCYGVSI------ 435

  Fly   446 WANTIGTAVGGLSSVLLAGWISFGSQIAAASGQLKSGMLPVSVKECVG-NVTLPEDPWVDQDQVF 509
            |...:|...|.|:.:.|:.|::.||.|..|. :.|:..||:|.:.||. |:|....|.:....|.
Mouse   436 WKLIMGALGGLLTGITLSFWVAIGSFIYPAP-ESKTLPLPLSTEHCVELNITTTVAPQISSRPVL 499

  Fly   510 --PLYRLSYHWVSPIGVVTAVVVGALVSLITKPADIKTLHAELISPVIHRFLPRECF 564
              ..|.|||.:.|.:|.:..:..|.::|.:|.....|.:...||.||.:.|    ||
Mouse   500 ADTWYSLSYLYFSAVGCLGCIAAGIIISFLTGKQRGKDIDPLLIRPVCNLF----CF 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31262	NP_732222.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	169/530 (32%)
Slc5a12	NP_001003915.1	SLC5-6-like_sbd	3..531	CDD:444915	173/550 (31%)