Protein Alignment CG31262 and SLC5A10

DIOPT Version :9

• Sequence 1: NP_001138069.2
• Gene: CG31262 / 318649
• FlyBaseID: FBgn0051262
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: XP_016879680.2
• Gene: SLC5A10 / 125206
• HGNCID: 23155
• Length: 649
• Species: Homo sapiens
• Alignment Length: 701
• Identity: 142/701 - (20%)
• Similarity: 240/701 - (34%)
• Gaps: 227/701 - (32%)

  Fly     5 RFGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIP 69
            :....|.:|:.....|:...||:            |....:|.|      ::.|.:..|:|...|
Human    15 QLSVADIIVITVYFALNVAVGIW------------SSCRASRNT------VNGYFLAGRDMTWWP 61

  Fly    70 VSITLYRVTS----IIGTPSE---------IYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQI 121
            :..:|:..:.    .||....         .:.:...|.|         :|.::|::|:|.:.:|
Human    62 IGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVL---------LALAWVFVPIYISSEI 117

  Fly   122 GSAYEYLGLRF-NSIIRTTASFM-YVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVT 184
            .:..||:..|: ...||...|.: .:..:.|.:...:|..||.:....|.|.:|..::.:.....
Human   118 VTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITAL 182

  Fly   185 YTFMGGLKAVVHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRL-----------ML 238
            ||..|||.||::||..|..:|.:..|.:.          :..||.....|:|           .:
Human   183 YTIAGGLAAVIYTDALQTLIMVVGAVILT----------IKAFDQIGGYGQLEAAYAQAIPSRTI 237

  Fly   239 ANTN------------PSPYVRHTVWSVLIGGFS-----FWTSVNAGGQHMVQRYMSLPSLKKSR 286
            |||.            ..|:.....|:.:..|.:     :|.:    .|.:|||.:|...|..::
Human   238 ANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCT----DQVIVQRSLSARDLNHAK 298

  Fly   287 QASFI------FTIGVSI---FIALCCFMGLLLFSKYKDCDPRSAGMILNDD------------- 329
            ..|.:      ..:|:.|   .|:...|.|..::.     :.....:...||
Human   299 AGSILASYLKMLPMGLIIMPGMISRALFPGAHVYE-----ERHQVSVSRTDDVGCVVPSECLRAC 358

  Fly   330 ----------------QLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIV 378
                            :|:|:          |:.||.||.:..|.:|||:|.||:.|.:|..||.
Human   359 GAEVGCSNIAYPKLVMELMPI----------GLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIW 413

  Fly   379 RGFFKMEP--SERQSTILIKTCI-----IFQGILAFLIVF---LLQHLRGI-------------- 419
            |   ::.|  .||:..::.:|.|     ..|..|:||:..   |.::|.|:
Human   414 R---RLRPRSGERELLLVGRTGIPSTPPAPQSRLSFLLPETPPLERYLLGLVVMDLWLVIVALIG 475

  Fly   420 LSVC-----------------NSISSITAGTSFGVFTLGMLFPWANTIGTAVGGLSSVLLAGWIS 467
            :||.                 .|::|..|.....||.||:.:..||..|...|     |:||
Human   476 VSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWG-----LIAG--- 532

  Fly   468 FGSQIAAASGQLKSGMLPVSVKECVGNVTLPEDPWVDQDQVFPLYRLSYHWVSPIGVVTAVVVGA 532
                            |.|.....|.....|..|..:.| ..|....|.|::. ..|....:.||
Human   533 ----------------LVVGATRLVLEFLNPAPPCGEPD-TRPAVLGSIHYLH-FAVALFALSGA 579

  Fly   533 LV---SLITKP-----------------ADIKTLHAELISPVIHRFLPREC 563
            :|   ||:|.|                 ..:.|...:..:|..|.|..|.|
Human   580 VVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVC 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	128/634 (20%)
SLC5A10	XP_016879680.2	SLC5-6-like_sbd	17..649	CDD:320982	142/699 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146457
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750