Protein Alignment CG31262 and SLC5A11

DIOPT Version :9

• Sequence 1: NP_001138069.2
• Gene: CG31262 / 318649
• FlyBaseID: FBgn0051262
• Length: 579
• Species: Drosophila melanogaster
• Sequence 2: NP_001339171.1
• Gene: SLC5A11 / 115584
• HGNCID: 23091
• Length: 675
• Species: Homo sapiens
• Alignment Length: 618
• Identity: 141/618 - (22%)
• Similarity: 249/618 - (40%)
• Gaps: 145/618 - (23%)

  Fly     7 GTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPVS 71
            |.:..|||..:.:|:.|   .:..:|.|....|.                 |.:...:|...||.
Human    27 GDIAVLVLYFLFVLAVG---LWSTVKTKRDTVKG-----------------YFLAGGDMVWWPVG 71

  Fly    72 ITLYRVTSIIGTPSEIYHY------GTQYYLIIVAIILQG----IAFSYVYLPVYSALQIGSAYE 126
            .:|:  .|.:|:.    |:      |....:.:.|..|.|    :..::::||:|.|.|:.:..|
Human    72 ASLF--ASNVGSG----HFIGLAGSGAATGISVSAYELNGLFSVLMLAWIFLPIYIAGQVTTMPE 130

  Fly   127 YL-----GLRFNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHL--IGLVIILACVT 184
            ||     |:|...|:.....|:|:|   |.:...:|..|:.:.|...|:.:|  :||:.|.|  .
Human   131 YLRKRFGGIRIPIILAVLYLFIYIF---TKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITA--V 190

  Fly   185 YTFMGGLKAVVHTDVWQVAVMF---LSLVAVAFLAIYYSNGL-----VAVFDDAEQGGRLMLANT 241
            ||..|||.||::||..|..:|.   |:|:..:|.|:....||     :|:..:..:.....|...
Human   191 YTVAGGLAAVIYTDALQTLIMLIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPRE 255

  Fly   242 NP-----SPYVRHTVWSVLIGGFS-----FWTSVNAGGQHMVQRYMSLPSLKKSR----QASFIF 292
            :.     .|......|..::.|.|     :|.:    .|.:|||.::..:|..::    .|:::.
Human   256 DAFHIFRDPLTSDLPWPGVLFGMSIPSLWYWCT----DQVIVQRTLAAKNLSHAKGGALMAAYLK 316

  Fly   293 TIGVSIFIALCCFMGL---LLFSKYKDC-DPRSAGMILND-----DQLLPLFVVQSVGHIYGMPG 348
            .:.:.|.:    |.|:   :||.....| ||.....|.::     |...|..|::.:.  .|:.|
Human   317 VLPLFIMV----FPGMVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLP--TGLRG 375

  Fly   349 LFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEPSERQSTILIKTCIIFQGILAFLIVFLL 413
            |.:|.:..|.:|||:|.||:.|.:|..|: ....:...||::..|:.:..::...:::.|.:.::
Human   376 LMMAVMVAALMSSLTSIFNSASTIFTMDL-WNHLRPRASEKELMIVGRVFVLLLVLVSILWIPVV 439

  Fly   414 QHLRG--ILSVCNSISSITAGTSFGVFTLGMLFPWANTIGTAVGGLSSVLLAGWISFGSQIAAAS 476
            |..:|  :.....||||........||.:|..:...|..|...|.:|.:||
Human   440 QASQGGQLFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKGAFWGLISGLLL-------------- 490

  Fly   477 GQLKSGMLPVSVKECVGNVTLPED-----PWVDQDQVFPLYRLSYHWV---SPIGVVTAVVVGAL 533
                            |.|.|..|     |..||....|:...|.|::   ..:..||.:.| :.
Human   491 ----------------GLVRLVLDFIYVQPRCDQPDERPVLVKSIHYLYFSMILSTVTLITV-ST 538

  Fly   534 VSLITKPADIKTLHAELIS---------PVIHR 557
            ||..|:|..     .|::|         ||:.:
Human   539 VSWFTEPPS-----KEMVSHLTWFTRHDPVVQK 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	129/570 (23%)
SLC5A11	NP_001339171.1	SLC5sbd_SGLT6	28..675	CDD:271381	140/617 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146473
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850