DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31262 and LOC100488353

DIOPT Version :9

Sequence 1:	NP_001138069.2	Gene:	CG31262 / 318649	FlyBaseID:	FBgn0051262	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_002936886.2	Gene:	LOC100488353 / 100488353	-ID:	-	Length:	606	Species:	Xenopus tropicalis

Alignment Length:	560	Identity:	172/560 - (30%)
Similarity:	291/560 - (51%)	Gaps:	51/560 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FGTVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPV 70
            |...||:|..|:.|:|...|||: |...:.||..                .|:|.|.|:|..:||
Frog    10 FSPWDYVVFAAVLLISAVIGIYY-AFAGRRKNTS----------------QEFLTGGRSMSALPV 57

  Fly    71 SITL----YRVTSIIGTPSEIYHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEYLGLR 131
            :::|    ....:::|||:::|.:|..|.:...:.:...|..:.::|||:..|.|.|.||||.||
Frog    58 ALSLTASFMSAVTVLGTPADVYRFGAIYSMFAFSYVFVVIICAEIFLPVFYRLNITSTYEYLELR 122

  Fly   132 FNSIIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVII--LACVTYTFMGGLKAV 194
            ||..:|...:.:::..::.|...::|.|||:|:||||.|  |.|.:..  |.|..|..:||:|||
Frog   123 FNKCVRILGTVIFIIEMVLYTGIVIYAPALALNQVSGFN--LWGAMTATGLVCTFYCTLGGIKAV 185

  Fly   195 VHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLANTNPSPYVRHTVWSVLIGGF 259
            :.|||:|:.:|....:||....:....|:..:.:|:..||||...:.:|.|..|||.|:::|||.
Frog   186 IWTDVFQIVIMVAGFIAVIIRGVVVQGGIQTIINDSYYGGRLNFWDFDPQPLRRHTFWTIVIGGT 250

  Fly   260 SFWTSVNAGGQHMVQRYMSLPSLKKSRQASFIFTIGVSIFIALCCFMGLLLFSKYKDCDPRSAGM 324
            ..|..:....|..||||:|..:..:::.:.:|..||:.|.:|.....||:|:|.||||||.::.:
Frog   251 FLWVGIYGVNQSQVQRYISCKTKGQAKLSLYINLIGLMIILACAVLCGLILYSVYKDCDPWTSQI 315

  Fly   325 ILNDDQLLPLFVVQSVGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEPSER 389
            |...|||:|..|:..:....|:||||:|..:...||::||..|.::.|.:||:::.:..:  ||.
Frog   316 ISAPDQLMPYLVLDILQGYPGVPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYTHL--SEN 378

  Fly   390 QSTILIKTCIIFQGILAFLIVFLLQHLRGILSVCNSISSITAGTSFGVFTLGMLFPWANTIGTAV 454
            :.:.:.|......|||...:..:...:..::....||.::..|...|:|:||:.||:.|::|..|
Frog   379 KLSWISKGMSALYGILCIAMAAVASFMGSVIQAALSIFAMVGGPLLGLFSLGLFFPFCNSVGAIV 443

  Fly   455 GGLSSVLLAGWISFGSQIAAASGQLKSGMLPVSVKECVGNVTLPEDPWVDQ---------DQVFP 510
            |.|....::.|...|:||.....: :|..||:|:..|  |.:..:..|...         ..:.|
Frog   444 GLLFGFSMSLWAGIGAQIYPPLPE-RSRPLPLSIAGC--NFSTMDTNWTSMTTEPTMAMVTNLIP 505

  Fly   511 L------------YRLSYHWVSPIGVVTAVVVGALVSLIT 538
            |            |.|||.:.|.:|.:..::||.:|||::
Frog   506 LDTSERPVLADYWYSLSYLYFSTLGTIVTILVGVIVSLMS 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	165/539 (31%)
LOC100488353	XP_002936886.2	SLC5-6-like_sbd	10..550	CDD:382020	172/560 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.020