DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31205 and hgfa

DIOPT Version :9

Sequence 1:	NP_001287432.1	Gene:	CG31205 / 318626	FlyBaseID:	FBgn0051205	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	XP_005164799.1	Gene:	hgfa / 493781	ZFINID:	ZDB-GENE-041014-2	Length:	712	Species:	Danio rerio

Alignment Length:	287	Identity:	68/287 - (23%)
Similarity:	105/287 - (36%)	Gaps:	79/287 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CGIFNEKQYNSDN--IIAEPTEHPWV---VRIVG-----VTKDGS--------NTLLCTGILIDS 75
            ||:...|..:||:  :...|....::   .||||     ..:|||        |...|.|.||..
Zfish   446 CGLERCKSMSSDDHQMSGGPKPSCFIHKTTRIVGGMRVQRAEDGSWVVSIQKGNRHWCGGSLIRE 510

  Fly    76 RRVVTAAHCVS---KDESESIYGVVFG-----DSDSSNINLVSAVTVHPDYSPRKFENDLAIIEL 132
            ..|:|...|.|   .|.||  |.|..|     .|..:....::.|...|:.|      :||:::|
Zfish   511 EWVLTDQQCFSTCVPDLSE--YTVQVGLLHLNASAGTQALRIAHVVCGPEGS------NLALLKL 567

  Fly   133 TKEVVFSDLVQPICLPSVSEMVPGSETSNSKLIVAGLEGPSFDRRHSATQRL-------DKR--- 187
            |.....|:.|:.:.||     |.|...:...|.:....|.:....|..:.::       :||
Zfish   568 TTPAPLSEHVRTVQLP-----VAGCAVAEGTLCLMYGWGDTKGTGHEGSLKMVGLPIVSNKRCSQ 627

  Fly   188 -----IKMTYTKI------DSKECHEKQARFPEELICGHTERSPLSGSALTEASGTPRQFHLLGI 241
                 :.:|.|||      |...| ||....|  |:|...|...:.|.::...          |.
Zfish   628 SHNGILPITETKICAGGKRDQGVC-EKDYGGP--LVCQEGESKVIVGVSINGR----------GC 679

  Fly   242 AVAGFFSSDLDHQGYLNIRPHLDWISK 268
            |||      .....::|:..:.:||.|
Zfish   680 AVA------RRPAVFVNVAFYSEWIRK 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31205	NP_001287432.1	Tryp_SPc	44..>168	CDD:304450	38/147 (26%)
hgfa	XP_005164799.1	PAN_AP_HGF	<50..107	CDD:238532
		KR	111..192	CDD:238056
		KR	195..275	CDD:214527
		KR	287..367	CDD:214527
		KR	374..451	CDD:214527	2/4 (50%)
		Tryp_SPc	476..698	CDD:214473	59/253 (23%)
		Tryp_SPc	477..701	CDD:238113	61/256 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575867
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930