DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG31205 and HGF

DIOPT Version :10

Sequence 1:NP_732543.2 Gene:CG31205 / 318626 FlyBaseID:FBgn0051205 Length:274 Species:Drosophila melanogaster
Sequence 2:NP_000592.3 Gene:HGF / 3082 HGNCID:4893 Length:728 Species:Homo sapiens


Alignment Length:277 Identity:67/277 - (24%)
Similarity:106/277 - (38%) Gaps:54/277 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 TITTL-HPTIQAASVGQECGIFNEKQYNSDNIIAEPTEHPWVVRIVGVTKDGSNTLLCTGILIDS 75
            ||..| ||.|..|..         ||....|.|...|...|:|.:     ...|..:|.|.||..
Human   476 TIVNLDHPVISCAKT---------KQLRVVNGIPTRTNIGWMVSL-----RYRNKHICGGSLIKE 526

  Fly    76 RRVVTAAHCV-SKD--ESESIYGV----VFGDSDSSNINLVSAVTVHPDYSPRKFENDLAIIELT 133
            ..|:||..|. |:|  :.|:..|:    ..||.....:..||.:...|:.|      ||.:::|.
Human   527 SWVLTARQCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLVYGPEGS------DLVLMKLA 585

  Fly   134 KEVVFSDLVQPICLPSVSEMVPGSETSNSKLIVAGLEGPSFDRRHSATQRLDKRIKMTYTKI-DS 197
            :..|..|.|..|.||:....:| .:||.|          .:...::.....|..:::.:..| .:
Human   586 RPAVLDDFVSTIDLPNYGCTIP-EKTSCS----------VYGWGYTGLINYDGLLRVAHLYIMGN 639

  Fly   198 KEC---HEKQARFPEELICGHTERSPLSGSALTEAS-GTP------RQFHLLGIAVAGFFSSDLD 252
            ::|   |..:....|..||...|:   .||...|.. |.|      :...:||:.|.|...:..:
Human   640 EKCSQHHRGKVTLNESEICAGAEK---IGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPN 701

  Fly   253 HQG-YLNIRPHLDWISK 268
            ..| ::.:..:..||.|
Human   702 RPGIFVRVAYYAKWIHK 718

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31205NP_732543.2 Tryp_SPc 44..>168 CDD:473915 35/130 (27%)
HGFNP_000592.3 PAN_APPLE 39..122 CDD:238074
KR 126..208 CDD:214527
KR 210..290 CDD:214527
KR 304..384 CDD:214527
KR 388..470 CDD:238056
Tryp_SPc 494..716 CDD:214473 55/246 (22%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.