DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31205 and mst1

DIOPT Version :9

Sequence 1:	NP_001287432.1	Gene:	CG31205 / 318626	FlyBaseID:	FBgn0051205	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_694512.1	Gene:	mst1 / 259260	ZFINID:	ZDB-GENE-020806-3	Length:	709	Species:	Danio rerio

Alignment Length:	286	Identity:	60/286 - (20%)
Similarity:	104/286 - (36%)	Gaps:	66/286 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 ITTLHPTIQAASVGQECGIFNEKQYNSDNII-AEPTEHPWVVRIVGVTKDGSNTLLCTGILIDSR 76
            :..:.||.:...  .|||...::..:...|: ..|...||.|.:    :|......|.|.|:.|.
Zfish   455 VPIIGPTTEVEF--NECGKREDRLRSRLRIVGGTPGNSPWTVSL----RDRKGNHFCGGSLVSSE 513

  Fly    77 RVVTAAHCVSKDESE-----SIYGVVF-----GDSDSSNINLVSAVTVHPDYSPRKFENDLAIIE 131
            .|::...|.|....:     ::.|.:|     |:.|...|:|...|.     .|.  |:.|.:::
Zfish   514 WVISTKQCFSSCYVDLTGYTAMMGTLFRDPKEGEPDLQRISLTKIVC-----GPS--ESHLVMLQ 571

  Fly   132 LTKEVVFSDLVQPICLPSVSEMVPGSETSNSKLIVAG---LEGPSFDRRHSATQRLDKRIKMTYT 193
            |.....|::.|..||||....:||......    :||   .:|...:...:..|         ..
Zfish   572 LETPAQFNERVSQICLPPERYIVPDGTICE----IAGWGETKGKGDETVLNVAQ---------MP 623

  Fly   194 KIDSKECHEK-QARFPEELIC--------GHTER---SPLSGSALTEASGTPRQFHLLGIAVAGF 246
            .:.:|:|::. :.|..|..:|        |..||   .||       |......:.|.|:.:.
Zfish   624 VLSNKDCNQYFKGRVRENEMCTMAFQAGVGACERDYGGPL-------ACQNSDCWVLEGVIIP-- 679

  Fly   247 FSSDLDHQG----YLNIRPHLDWISK 268
             .....|.|    ::.:..::|||.|
Zfish   680 -MRRCGHAGQPNIFIRVSVYVDWIKK 704

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31205	NP_001287432.1	Tryp_SPc	44..>168	CDD:304450	31/133 (23%)
mst1	NP_694512.1	PAN_AP_HGF	24..105	CDD:238532
		KR	109..187	CDD:238056
		KR	192..271	CDD:214527
		KR	284..365	CDD:214527
		KR	370..451	CDD:238056
		Tryp_SPc	481..702	CDD:214473	52/254 (20%)
		Tryp_SPc	482..705	CDD:238113	55/257 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575878
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930