DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31205 and Mst1

DIOPT Version :9

Sequence 1:	NP_001287432.1	Gene:	CG31205 / 318626	FlyBaseID:	FBgn0051205	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_032269.3	Gene:	Mst1 / 15235	MGIID:	96080	Length:	716	Species:	Mus musculus

Alignment Length:	273	Identity:	58/273 - (21%)
Similarity:	97/273 - (35%)	Gaps:	81/273 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LHPTIQAASVGQECGIFNEKQYNSDNIIAEPTEHPWVVRIVGVTKDGSNTLLCTGILIDSRRVVT 80
            |.|..|.  |.::||...:|......:...|...||.|.:    ::......|.|.|:..:.|:|
Mouse   466 LDPPDQV--VFEKCGKRVDKSNKLRVVGGHPGNSPWTVSL----RNRQGQHFCGGSLVKEQWVLT 524

  Fly    81 AAHCV-SKDESESIYGVVF---------GDSDSSNINLVSAVTVHPDYSPRKFENDLAIIELTKE 135
            |..|: |..|..:.|.|..         |:::...:.:..||.     .|.  .:.|.:::|.:.
Mouse   525 ARQCIWSCHEPLTGYEVWLGTINQNPQPGEANLQRVPVAKAVC-----GPA--GSQLVLLKLERP 582

  Fly   136 VVFSDLVQPICLPSVSEMV-PGSE-----------TSNSKLIVAGLEGPSFDRRHSATQRLDKRI 188
            |:.:..|..||||....:| ||::           |||:.::            |.|:..:
Mouse   583 VILNHHVALICLPPEQYVVPPGTKCEIAGWGESIGTSNNTVL------------HVASMNV---- 631

  Fly   189 KMTYTKIDSKECHEKQARFPEELICGHTERSPLSGSALTEASGTPRQFHLLGIAVAGFFSSDLDH 253
                  |.::||:.|..        ||.:.|.:....|....|          |..|      |:
Mouse   632 ------ISNQECNTKYR--------GHIQESEICTQGLVVPVG----------ACEG------DY 666

  Fly   254 QGYLNIRPHLDWI 266
            .|.|....|..|:
Mouse   667 GGPLACYTHDCWV 679

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31205	NP_001287432.1	Tryp_SPc	44..>168	CDD:304450	33/145 (23%)
Mst1	NP_032269.3	PAN_1	25..96	CDD:278453
		KR	108..188	CDD:214527
		KR	191..269	CDD:214527
		KR	291..372	CDD:214527
		KR	377..459	CDD:214527
		Tryp_SPc	488..709	CDD:214473	51/249 (20%)
		Tryp_SPc	489..712	CDD:238113	51/248 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833178
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930