DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31205 and Hgf

DIOPT Version :9

Sequence 1:	NP_001287432.1	Gene:	CG31205 / 318626	FlyBaseID:	FBgn0051205	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_001276387.1	Gene:	Hgf / 15234	MGIID:	96079	Length:	728	Species:	Mus musculus

Alignment Length:	278	Identity:	65/278 - (23%)
Similarity:	105/278 - (37%)	Gaps:	54/278 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 TITTL-HPTIQAASVGQECGIFNEKQYNSDNIIAEPTEHPWVVRIVGVTKDGSNTLLCTGILIDS 75
            ||..| ||.|..|..         ||....|.|...|...|:|.:     ...|..:|.|.||..
Mouse   477 TIVNLDHPVISCAKT---------KQLRVVNGIPTQTTVGWMVSL-----KYRNKHICGGSLIKE 527

  Fly    76 RRVVTAAHCV---SKD--ESESIYGV----VFGDSDSSNINLVSAVTVHPDYSPRKFENDLAIIE 131
            ..|:||..|.   :||  :.|:..|:    ..|:.....|..:|.:...|:.|      ||.:::
Mouse   528 SWVLTARQCFPARNKDLKDYEAWLGIHDVHERGEEKRKQILNISQLVYGPEGS------DLVLLK 586

  Fly   132 LTKEVVFSDLVQPICLPSVSEMVPGSETSNSKLIVAGLEGPSFDRRHSATQRLDKRIKMTYTKID 196
            |.:..:..:.|..|.|||....:|...|       ..:.|..:....:|...|  |:...|. :.
Mouse   587 LARPAILDNFVSTIDLPSYGCTIPEKTT-------CSIYGWGYTGLINADGLL--RVAHLYI-MG 641

  Fly   197 SKEC---HEKQARFPEELICGHTERSPLSGSALTEAS-GTP------RQFHLLGIAVAGFFSSDL 251
            :::|   |:.:....|..:|...|:   .||...|.. |.|      :...:||:.|.|...:..
Mouse   642 NEKCSQHHQGKVTLNESELCAGAEK---IGSGPCEGDYGGPLICEQHKMRMVLGVIVPGRGCAIP 703

  Fly   252 DHQG-YLNIRPHLDWISK 268
            :..| ::.:..:..||.|
Mouse   704 NRPGIFVRVAYYAKWIHK 721

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31205	NP_001287432.1	Tryp_SPc	44..>168	CDD:304450	31/132 (23%)
Hgf	NP_001276387.1	PAN_APPLE	41..123	CDD:238074
		KR	127..209	CDD:214527
		KR	211..289	CDD:214527
		KR	305..385	CDD:214527
		KR	389..471	CDD:238056
		Tryp_SPc	495..719	CDD:214473	53/247 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833156
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930