Protein Alignment alpha-Man-Ic and MNL2

DIOPT Version :9

• Sequence 1: NP_733331.1
• Gene: alpha-Man-Ic / 318624
• FlyBaseID: FBgn0051202
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_013158.1
• Gene: MNL2 / 850746
• SGDID: S000004047
• Length: 849
• Species: Saccharomyces cerevisiae
• Alignment Length: 724
• Identity: 144/724 - (19%)
• Similarity: 232/724 - (32%)
• Gaps: 282/724 - (38%)

  Fly    55 NIPSND----NSLKDMNPD-DMRAKIKEMMMHAWRNYARVVWGTNEFRPISRRVHFGGDFATYKL 114
            :|..||    .....:.|| ||..:||::.|.:| |..:::..:|..|.           :|:.:
Yeast   143 SISQNDVHKIQPAMQLPPDVDMIKQIKDIFMKSW-NQEQLLLKSNLRRE-----------STWPI 195

  Fly   115 GATIIESLDTLHLMGLNKELRRSRDWIEK-SFHLDRVD-EALSVYELTSRLLCPMLTLYSLTGDS 177
              .:|:|||||:|.|..|..:.|.:.||. .|.:..:. |.:.:.::|:|:|..:|:.|.|:.|.
Yeast   196 --DLIDSLDTLYLCGETKLFQDSVNIIEDFDFRVPPLAMEVIDIPDITTRVLEGLLSAYELSMDK 258

  Fly   178 LYMDKAIHIADKILPAFDTPTGIP-----------RRL---VVPKEGST--------------LT 214
            ..::||.|:||.||.:||||..||           .|.   .||....|              |.
Yeast   259 RLLNKAKHVADFILRSFDTPNRIPILKYFWKSDLRNRFPDRTVPSGQLTTMALAFIRLSQLTRLN 323

  Fly   215 KYLSDISRT-----SEFGSLHLEFYY--------------------------------------- 235
            ||...:.|.     ..:....:||..
Yeast   324 KYFDAVERVFTTIRQSYNEFDMEFMLPDVVDASGCQLLTQEEIENGAHLKGSSIMKSINENFKFV 388

  Fly   236 -----------------LSEVSGYPVYR--ERVDAIREILAKTTRPNGLYPNAYCTKFGKWENYN 281
                             |.|.|.|..||  |:...|.|.|.|.   |.|:.::|....|..:|.|
Yeast   389 HCQQLGKFLNPPIDDNSLQEQSQYQAYRINEKTVPILENLFKI---NDLFQSSYDILDGSSKNAN 450

  Fly   282 C--------SMHRLYDTLL--------------------KSWIQSGR------------------ 300
            .        |.....|.::                    ||.|.|..
Yeast   451 AATMDPSIGSEVEAVDEIIEKRNFKDGTKKDSTKNTVGDKSLIDSQTFLTNSISNIFKFMTFRPM 515

  Fly   301 --TDTQNAD-TFKEAMLAVAQNLVVINPEDVTYVSTF-------RNGTLF-------HR------ 342
              ..|:|.. .|..::|..:|.:...|..|||...::       |.|.:.       ||
Yeast   516 LPKQTENKKFNFLNSILTKSQFMPTTNELDVTIRKSYDVSLYSCRLGGILGLSSRVPHRGGVNTK 580

  Fly   343 -------MRHSDCFAGGLFVL----------------------------GAAETQM------KHW 366
                   :..|:......|:|                            |..:::|      :.:
Yeast   581 YILPSSLLEMSEIITESCFMLMEEFDGLLPQKFELDPCTDETNGNCEFNGETKSRMIANGEYETF 645

  Fly   367 EKYAHIGI----------------------GLTDTCH---DSYWSSPT----------------R 390
            |....:||                      |:|:|.:   |:..||.:                .
Yeast   646 ENDLDVGIKVSNYGKGGNDQKAKRNVLSKDGITETQNIKGDTVGSSKSIAEIDGDEVTQIRRVFT 710

  Fly   391 LGPD-----TFAFTEESQQEIEPLQRNYYN-------LRPEVAETYLVLWRITHHPQYRLWGLEM 443
            ||.|     |...|..||.:..|....:.|       |...:.|:...::||:...::|..|.:.
Yeast   711 LGKDIKPHITTDDTMGSQWKNHPDWPFWVNKVESRRLLDSNIIESIFYMYRISGEQKWRSMGKQS 775

  Fly   444 VQAI-EKYCRMPYGYTGVMDVNNVTSEPDDVQG---SFFLGSTLKYLYLLFSDDDVVSLEQWVFN 504
            ...: ::...:..|..|:..:.......:.|..   |::...||||..|||||.|.|||::.:..
Yeast   776 FGILMQELMELNSGAKGLWQIKEFYENGEKVNNDLPSYWFSRTLKYYLLLFSDGDKVSLDKHILT 840

  Fly   505 SAGHFLPIK 513
            ..||.:..|
Yeast   841 QGGHIIKKK 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ic	NP_733331.1	Glyco_hydro_47	78..512	CDD:279825	134/693 (19%)
MNL2	NP_013158.1	LanC_like	197..848	CDD:414247	128/653 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X635
TreeFam	0	0.000	Not matched by this tool.
	4	3.910