DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment alpha-Man-Ic and MNS1

DIOPT Version :9

Sequence 1:	NP_733331.1	Gene:	alpha-Man-Ic / 318624	FlyBaseID:	FBgn0051202	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_175570.1	Gene:	MNS1 / 841584	AraportID:	AT1G51590	Length:	560	Species:	Arabidopsis thaliana

Alignment Length:	476	Identity:	165/476 - (34%)
Similarity:	257/476 - (53%)	Gaps:	40/476 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 SLKDMNPDD-----MRAKIKEMMMHAWRNYARVVWGTNEFRPISR--RVHFGGDFATYKLGATII 119
            :|||. |:|     .|.|:||.|:|||.:|.:..||.:|.:|.::  ...|||      ||||::
plant    84 TLKDA-PEDPVDKQRRQKVKEAMIHAWSSYEKYAWGKDELQPRTKDGTDSFGG------LGATMV 141

  Fly   120 ESLDTLHLMGLNKELRRSRDWIEKSFHLDRVDEALSVYELTSRLLCPMLTLYSLTGDSLYMDKAI 184
            :|||||::|||:::.:::|:|:..|...|: |...|::|.|.|::..:|:.|.|:||.::::||.
plant   142 DSLDTLYIMGLDEQFQKAREWVASSLDFDK-DYDASMFETTIRVVGGLLSAYDLSGDKMFLEKAK 205

  Fly   185 HIADKILPAFDTPTGIPRRLVVPKEGSTLTK--YLSDISRTSEFGSLHLEFYYLSEVSGYPVYRE 247
            .|||::|||::||||||..::..:.|:....  .....|..::.|:..|||..||:.:|.|.|::
plant   206 DIADRLLPAWNTPTGIPYNIINLRNGNAHNPSWAAGGDSILADSGTEQLEFIALSQRTGDPKYQQ 270

  Fly   248 RVDAIREILAKTTRPNGLYP------NA----YCTKFGKWENYNCSMHRLYDTLLKSWIQSGRTD 302
            :|:.:...|.|....:||.|      ||    ..|.||...:      ..|:.|||.|:|..:|.
plant   271 KVEKVITELNKNFPADGLLPIYINPDNANPSYSTTTFGAMGD------SFYEYLLKVWVQGNKTS 329

  Fly   303 TQN--ADTFKEAMLAVAQNLVVINPEDVTYVSTFRNGTLFHRMRHSDCFAGGLFVLGAAETQMKH 365
            ...  .|.::::|..:...:....|...||:.......|..:|....|||.|:..|||:......
plant   330 AVKPYRDMWEKSMKGLLSLVKKSTPSSFTYICEKNGNNLIDKMDELACFAPGMLALGASGYGPDE 394

  Fly   366 WEKYAHIGIGLTDTCHDSYWSSPTRLGPDTFAFTEESQQEIEPLQRNYYNLRPEVAETYLVLWRI 430
            .:|:..:...|..||::.|.|:||:|..:.:.||......:   ..::..||||..|:...|||:
plant   395 EKKFLSLAGELAWTCYNFYQSTPTKLAGENYFFTAGQDMSV---GTSWNILRPETVESLFYLWRL 456

  Fly   431 THHPQYRLWGLEMVQAIEKYCRMPYGYTGVMDVNNVTSEPDDVQGSFFLGSTLKYLYLLFSDDDV 495
            |.:..|:.||..:.||.||..|:..||.|:.|||  |...|:...||||..||||||||||...|
plant   457 TGNKTYQEWGWNIFQAFEKNSRVESGYVGLKDVN--TGAKDNKMQSFFLAETLKYLYLLFSPSSV 519

  Fly   496 VSLEQWVFNSAGHFLPIKGVN 516
            :||::||||:..|.|.|...|
plant   520 ISLDEWVFNTEAHPLKIVARN 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ic	NP_733331.1	Glyco_hydro_47	78..512	CDD:279825	154/449 (34%)
MNS1	NP_175570.1	Glyco_hydro_47	104..536	CDD:396217	154/449 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	379	1.000	Domainoid score	I166
eggNOG	1	0.900	-	-		E1_KOG2204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	396	1.000	Inparanoid score	I478
OMA	1	1.010	-	-		QHG54359
OrthoDB	1	1.010	-	-		D693882at2759
OrthoFinder	1	1.000	-	-		FOG0001280
OrthoInspector	1	1.000	-	-		mtm1139
orthoMCL	1	0.900	-	-		OOG6_100239
Panther	1	1.100	-	-	O	PTHR11742
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X635
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840