Protein Alignment alpha-Man-Ic and Edem2

DIOPT Version :10

• Sequence 1: NP_733331.1
• Gene: alpha-Man-Ic / 318624
• FlyBaseID: FBgn0051202
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_609611.1
• Gene: Edem2 / 34714
• FlyBaseID: FBgn0032480
• Length: 801
• Species: Drosophila melanogaster
• Alignment Length: 533
• Identity: 135/533 - (25%)
• Similarity: 225/533 - (42%)
• Gaps: 107/533 - (20%)

  Fly    31 IFTVGVIVITYIQCRAMMRESFQKNIPSNDNSLKDMNPDDMRAKIKEMMMHAWRNYARVVWGTNE 95
            ||.|.:.::  :.|..    |.:..:|:.:.|.|:.  .::|.:.::|..||:..|.:..:..:|
  Fly    18 IFLVAMCIV--VACVL----STETTMPTQNMSNKER--AELREEARDMFYHAYNAYMQNAYPADE 74

  Fly    96 FRPISRRVHFGG--------DFATYKLGATIIESLDTLHLMGLNKELRRSRDWIEKSFHLDRVDE 152
            ..|:|.:..:.|        |........|::::||||.|:|...|...:...:.:....|. |.
  Fly    75 LMPLSCKGRYRGVTPSRGDMDDILGNFSMTLVDTLDTLVLLGDFTEFDHAVKLVIRDVQFDS-DI 138

  Fly   153 ALSVYELTSRLLCPML--------------TLYSLTGDSLYMDKAIHIADKILPAFDTPTGIPRR 203
            .:||:|...|::..:|              |::...|:.|.|.:  .:..::||||:|.||||..
  Fly   139 IVSVFETNIRMVGGLLSAHILAEYLQKHADTMHWYKGELLEMSR--ELGYRLLPAFNTSTGIPHA 201

  Fly   204 LVVPKEG---STLTKYLSDISRTSEFGSLHLEFYYLSEVSGYPVYRERVDAIREILAKTT-RPNG 264
            .|..:.|   ..|.|  |..:.|:..|::.|||..||.::|.|::..|..|..:.|.|.. |.:.
  Fly   202 RVNLRLGMKDPMLKK--SRETCTACAGTILLEFAALSRLTGDPIFEVRAHAAMDALWKLRHRGSD 264

  Fly   265 LYPNAYCTKFGKW----ENYNCSMHRLYDTLLKSWIQSGRTDTQNADTFKEAMLAVAQNLVVINP 325
            |.........|.|    ......:...|:.|.||::..|  |.:....|.....||
  Fly   265 LMGTVLNVHSGDWVRRDSGVGAGIDSYYEYLFKSYVLLG--DDKYLARFNRHYNAV--------- 318

  Fly   326 EDVTYVSTFRNG-----TLFHR--------MRHSDCFAGGLFVLG-----AAET-QMKHWEKYAH 371
              :.|||   .|     .|.||        |.....|..||.||.     |.:| :|.:.....|
  Fly   319 --MKYVS---EGPMLLDVLMHRPHAKSKNFMDSLLAFWPGLQVLSGDLKPAVQTHEMLYQVMQMH 378

  Fly   372 IGIGLTDTCHDSYWSSPTRLGPDTFAFTEESQQEIEPLQRNYYNLRPEVAETYLVLWRITHHPQY 436
            ..|                  |:  |||.:.|     :....:.||||..|:...|:|.|....|
  Fly   379 TFI------------------PE--AFTVDFQ-----IHWGQHPLRPEFIESTYFLYRATGDHHY 418

  Fly   437 RLWGLEMVQAIEKYCRMPYGYTGVMDVNNVTSEPDDVQGSFFLGSTLKYLYLLFSD--DDVVSLE 499
            ...|.:.::.::::.::..||..|.||.  |.:.:|...||.|..|:|||:|||||  |.:::::
  Fly   419 LQVGKKALKTLQQHAKVSCGYAAVNDVR--TGKHEDRMDSFVLSETIKYLFLLFSDPQDLIINVD 481

  Fly   500 QWVFNSAGHFLPI 512
            ::||.:..|.||:
  Fly   482 EFVFTTEAHLLPL 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ic	NP_733331.1	Glyco_hydro_47	78..512	CDD:460241	125/484 (26%)
Edem2	NP_609611.1	Glyco_hydro_47	57..494	CDD:460241	125/484 (26%)
		PA_EDEM3_like	645..770	CDD:239041