Protein Alignment alpha-Man-Ic and Edem1

DIOPT Version :10

• Sequence 1: NP_733331.1
• Gene: alpha-Man-Ic / 318624
• FlyBaseID: FBgn0051202
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001259152.1
• Gene: Edem1 / 31154
• FlyBaseID: FBgn0023511
• Length: 1004
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 134/509 - (26%)
• Similarity: 226/509 - (44%)
• Gaps: 105/509 - (20%)

  Fly    70 DMRAKIKEMMMHAWRNYARVVWGTNEFRPISRRVHFGGDFATYKLGATIIESLDTLHLMGLNKEL 134
            ::|..::.|..||:..|.|.....:|.||::...|  ..:.:|.|  |:|::||||..||...|.
  Fly    40 ELREDVRRMFQHAYDGYLRHASNYDELRPLTCDGH--DTWGSYSL--TLIDALDTLATMGNFTEF 100

  Fly   135 RRSRDWIEKSFHLDRVDEALSVYELTSRLLCPMLTLYSLT--------------GDSLYMDKAIH 185
            ||:...:|:....|| |..:||:|...|::..:|:.:.|:              |..|.:  |..
  Fly   101 RRAARLLEEKMDFDR-DINVSVFETNIRIVGGLLSAHLLSKRAGVELEPGWPCKGPLLRL--AED 162

  Fly   186 IADKILPAFDTPTGIP-----RRLVVPKEGSTLTKYLSDISRTSEFGSLHLEFYYLSEVSGYPVY 245
            :|.::||||.|.||:|     .|..||| |.|      .|:.|:..|:..:||..||.::|..:|
  Fly   163 VARRLLPAFVTNTGMPYGTVNLRYGVPK-GET------SITCTAGVGTFLIEFGTLSRLTGKTIY 220

  Fly   246 RE-RVDAIREILAKTTRPNGLYPNAYCTKFGKW----ENYNCSMHRLYDTLLKSWIQSGRTDTQN 305
            .: .:.|:..:.|..: |.||:.|....:.|:|    ......:..|::.|:|:.:...|.:.
  Fly   221 EDVAMKAVHALWAYRS-PIGLFGNHIDVQSGRWTALDSGIGAGVDSLFEYLVKASVLLNRPEL-- 282

  Fly   306 ADTFKEAMLAVAQNL--------VVINPEDVTYVSTFRNGTLFHRMRHSDCFAGGLFVLGAAETQ 362
            .:.|.||..|:.:.:        |.:|...|| :..|::...|        :.|.|.::|..|..
  Fly   283 LELFHEARAAIDKYMRKEDWYVWVGMNKGRVT-LPVFQSLEAF--------WPGILSIIGDTEPA 338

  Fly   363 MKHWEKYAHIGIGLTDTCHDSYWSSPTRLGPDTFAFTEE----SQQEIEPLQRNYYNLRPEVAET 423
            ::...:|  ||:          |..        :.|..|    :..|..| .|..|.||||:.|:
  Fly   339 LRTISRY--IGV----------WKK--------YGFLPEFYNIAAGEASP-NREVYPLRPELIES 382

  Fly   424 YLVLWRITHHPQYRLWGLEMVQAIEKYCRMPYGYTGVMDVNNVTSEPDDVQGSFFLGSTLKYLYL 488
            .:.|:|.|.:.....:|..|::.:|...:...||..:.:|  ||.|.::...||||..|.|||||
  Fly   383 AMYLYRATGNEYLLEFGEHMLETLEFSAKTKCGYATIRNV--VTHEKENRMESFFLAETSKYLYL 445

  Fly   489 LF-----------------SDDD--VVSLEQWVFNSAGHFLPIKGVNPMYRQHN 523
            ||                 ::||  ||....::||:..|.:.:..::..: .||
  Fly   446 LFDEENFLHNDGSGGELLSTEDDVCVVQAGAYIFNTEAHPMDMSALHCCH-AHN 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ic	NP_733331.1	Glyco_hydro_47	78..512	CDD:460241	131/488 (27%)
Edem1	NP_001259152.1	Glyco_hydro_47	48..486	CDD:460241	131/486 (27%)