Protein Alignment alpha-Man-Ic and mnl1

DIOPT Version :10

• Sequence 1: NP_733331.1
• Gene: alpha-Man-Ic / 318624
• FlyBaseID: FBgn0051202
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_594434.1
• Gene: mnl1 / 2541981
• PomBaseID: SPAC23A1.04C
• Length: 787
• Species: Schizosaccharomyces pombe
• Alignment Length: 515
• Identity: 123/515 - (23%)
• Similarity: 221/515 - (42%)
• Gaps: 77/515 - (14%)

  Fly    31 IFTVGVIVITYIQCRAMMRESFQKNIPSNDNSLKDMNPDDMRAKIKEMMMHAWRNYARVVWGTNE 95
            ||.|.:|::...:         :.:|....||.:.:   ::|...:.:..|.:.||.:..:..:|
pombe     7 IFCVCLILLCIFK---------ENSIVGAINSARMV---ELRETSRRLFYHGYNNYMQFAFPNDE 59

  Fly    96 FRPISRRVHFGGDF------------ATYKLGATIIESLDTLHLMGLNKELRRSRDWIEKSFHLD 148
            ..|:|.. ..|.|:            ..|.|  |:::.||||.::|..:..:.:.|.:....:.:
pombe    60 LAPLSCE-GLGPDYENPNNIGVNDVRGDYLL--TLVDVLDTLVVLGDREGFQDAVDKVIHHINFE 121

  Fly   149 RVDEALSVYELTSRLLCPMLTLYSLTGDSLY-----------MDKAIHIADKILPAFDTPTGIPR 202
            | |..:.|:|.|.|:|..:|:.:....:..|           :..|..:|:::||||.||||||.
pombe   122 R-DTKVQVFEATIRILGGLLSSHIFASEEKYGFQIPLYKGELLTLATELAERLLPAFRTPTGIPF 185

  Fly   203 RLVVPKEGSTLTKYLSDISRTSEFGSLHLEFYYLSEVSGYPVYRERVDAIREILAKTTRPNGLYP 267
            ..:...:|....:...:.:..:  .||.|||..|:.::|...::...:.....:.|.....||..
pombe   186 ARINLMKGVAYREVTENCAAAA--SSLVLEFSMLTALTGNNKFKASAENAFFSVWKRRSGIGLLG 248

  Fly   268 NAYCTKFGKW----ENYNCSMHRLYDTLLKSWIQSGRTDTQNADTFKEAMLAVAQNLVVINPEDV 328
            |:.....|:|    ......:...|:...||:|..|  |.:..:.:::::.::......:|  :.
pombe   249 NSIDVLSGRWIYPVSGVGAGIDSFYEYAFKSYIFLG--DPRYLEVWQKSLESLRHYTASLN--EY 309

  Fly   329 TYVSTF-RNGTLFHRMRHS-DCFAGGLFVLGAAETQMKHWEKYAHIGIGLTDTCHDSYWSSPTRL 391
            .|.:.: .||.:..|...| ..:..||.|| |.|.:             |....|..|:|...:.
pombe   310 YYQNVYSANGMVMSRWVDSLSAYFPGLLVL-AGELE-------------LAKKMHLYYFSIYLKF 360

  Fly   392 G--PDTFAFTEESQQEIEPLQRNYYNLRPEVAETYLVLWRITHHPQYRLWGLEMVQAIEKYCRMP 454
            |  |:.:....:|      ::.|.|.||||.||:...|:|.|....|...|..::..||.:...|
pombe   361 GQLPERYNLYTKS------IELNGYPLRPEFAESTYYLYRATKDVFYLHVGELLLSNIENHLWTP 419

  Fly   455 YGYTGVMDVNNVTSEPDDVQGSFFLGSTLKYLYLLFSDDDVV--SLEQWVFNSAGHFLPI 512
            .|:..|.::...|.  .:...||||..|||||:|||.||:.:  |...::|.:.||..|:
pombe   420 CGFAAVENLEKYTL--SNRMESFFLSETLKYLFLLFDDDNPIHRSHHDFIFTTEGHLFPV 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ic	NP_733331.1	Glyco_hydro_47	78..512	CDD:460241	114/466 (24%)
mnl1	NP_594434.1	Glyco_hydro_47	42..477	CDD:460241	114/466 (24%)