Protein Alignment alpha-Man-Ic and Man1a

DIOPT Version :9

• Sequence 1: NP_733331.1
• Gene: alpha-Man-Ic / 318624
• FlyBaseID: FBgn0051202
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_006512631.1
• Gene: Man1a / 17155
• MGIID: 104677
• Length: 746
• Species: Mus musculus
• Alignment Length: 487
• Identity: 197/487 - (40%)
• Similarity: 285/487 - (58%)
• Gaps: 34/487 - (6%)

  Fly    45 RAMMRESFQKNIPSNDNSLKDMNPDDMRAKIKEMMMHAWRNYARVVWGTNEFRPISRRVHFGGDF 109
            |.:.:..|...:...:....|....:.||||||||.|||.||.|..||.||.:|||:..|....|
Mouse   262 RGLPKVDFLPPVGVENREPADATIREKRAKIKEMMTHAWNNYKRYAWGLNELKPISKEGHSSSLF 326

  Fly   110 ATYKLGATIIESLDTLHLMGLNKELRRSRDWIEKSFHLD-RVDEALSVYELTSRLLCPMLTLYSL 173
            ...| ||||:::||||.:||:..|.:.::.||:|  :|| .|:..:||:|:..|.:..:|:.|.|
Mouse   327 GNIK-GATIVDALDTLFIMGMKTEFQEAKSWIKK--YLDFNVNAEVSVFEVNIRFVGGLLSAYYL 388

  Fly   174 TGDSLYMDKAIHIADKILPAFDTPTGIPRRLVVPKEGSTLTKYLSDISRT-----------SEFG 227
            :|:.::..||:.:..|:||||.||:|||..|:..|.|         |.|.           :|||
Mouse   389 SGEEIFRKKAVELGVKLLPAFHTPSGIPWALLNMKSG---------IGRNWPWASGGSSILAEFG 444

  Fly   228 SLHLEFYYLSEVSGYPVYRERVDAIREILAKTTRPNGLYPNAYCTKFGKWENYNCSMHRL----Y 288
            :|||||.:||.:||.||:.|:|..||.:|.|..:|.|||||......|:|..::.|:..|    |
Mouse   445 TLHLEFMHLSHLSGDPVFAEKVMKIRTVLNKLDKPEGLYPNYLNPSSGQWGQHHVSVGGLGDSFY 509

  Fly   289 DTLLKSWIQSGRTDTQNADTFKEAMLAVAQNLVVINPEDVTYVSTFRNGTLFHRMRHSDCFAGGL 353
            :.|||:|:.|.:||.:....:.:|:.|:..:|:..:...:||::.::.|.|.|:|.|..|||||:
Mouse   510 EYLLKAWLMSDKTDLEAKKMYFDAVQAIETHLIRKSSGGLTYIAEWKGGLLEHKMGHLTCFAGGM 574

  Fly   354 FVL---GAAETQMKHWEKYAHIGIGLTDTCHDSYWSSPTRLGPDTFAFTEESQQEIEPLQRNYYN 415
            |.|   ||.|.:.:|   |..:|..:..|||:||..:..:|||:.|.|....:.........||.
Mouse   575 FALGADGAPEARAQH---YLELGAEIARTCHESYNRTYVKLGPEAFRFDGGVEAIATRQNEKYYI 636

  Fly   416 LRPEVAETYLVLWRITHHPQYRLWGLEMVQAIEKYCRMPYGYTGVMDVNNVTSEPDDVQGSFFLG 480
            |||||.|||:.:||:||.|:||.|..|.|:|:|.:||:..||:|:.||.......||||.||||.
Mouse   637 LRPEVIETYMYMWRLTHDPKYRTWAWEAVEALESHCRVNGGYSGLRDVYIARESYDDVQQSFFLA 701

  Fly   481 STLKYLYLLFSDDDVVSLEQWVFNSAGHFLPI 512
            .|||||||:|||||::.||.|:||:..|..||
Mouse   702 ETLKYLYLIFSDDDLLPLEHWIFNTEAHPFPI 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ic	NP_733331.1	Glyco_hydro_47	78..512	CDD:279825	186/452 (41%)
Man1a	XP_006512631.1	SdhA	<178..305	CDD:393461	16/42 (38%)
		Glyco_hydro_47	295..733	CDD:366693	186/452 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839762
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54359
OrthoDB	1	1.010	-	-		D263455at33208
OrthoFinder	1	1.000	-	-		FOG0001280
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100239
Panther	1	1.100	-	-	O	PTHR11742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X635
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.720