DRSC/TRiP Functional Genomics Resources

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Protein Alignment alpha-Man-Ic and Edem2

DIOPT Version :9

Sequence 1:NP_733331.1 Gene:alpha-Man-Ic / 318624 FlyBaseID:FBgn0051202 Length:526 Species:Drosophila melanogaster
Sequence 2:NP_663512.2 Gene:Edem2 / 108687 MGIID:1915540 Length:577 Species:Mus musculus


Alignment Length:513 Identity:127/513 - (24%)
Similarity:216/513 - (42%) Gaps:112/513 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 PSNDNSLKDMNPDDMRAKIKEMMMHAWRNYARVVWGTNEFRPISRRVH-FGGDFATYKLGATIIE 120
            |..|.:..|  |...|.::|.|..||:.:|....:..:|.||::...| ..|.|:     .|:|:
Mouse    23 PGPDGTAPD--PAHYRERVKAMFYHAYDSYLENAFPYDELRPLTCDGHDTWGSFS-----LTLID 80

  Fly   121 SLDTLHLMGLNKELRRSRDWIEKSFHLDRVDEALSVYELTSRLLCPMLTLYSL------------ 173
            :||||.::|...|.:|..:.::.:...| :|...||:|...|::..:|:.:.|            
Mouse    81 ALDTLLILGNTSEFQRVVEVLQDNVDFD-IDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGW 144

  Fly   174 --TGDSLYMDKAIHIADKILPAFDTPTGIPRRLVVPKEGSTLTKYLSDISRTSEFGSLHLEFYYL 236
              :|..|.|  |...|.|:||||.||||:|...|....|  :....:.::.|:..|:..:||..|
Mouse   145 PCSGPLLRM--AEEAARKLLPAFQTPTGMPYGTVNLLHG--VNPGETPVTCTAGIGTFIVEFATL 205

  Fly   237 SEVSGYPVYRE--RVDAIREILAKTTRPNGLYPNAYCTKFGKWENYNCSMHRLYDTLLKSWIQSG 299
            |.::|.||:.:  ||..:|  |.::....||..|......|||...:..:....|:..:..:   
Mouse   206 SSLTGDPVFEDVARVALMR--LWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLV--- 265

  Fly   300 RTDTQNADTFKEAMLAVAQNLVVINPEDVTYVSTFRNGTLFHR----------------MRHSDC 348
                      |.|:|...:.|:.:..|   |....||.|.|..                .:..:.
Mouse   266 ----------KGAILLQDKKLMAMFLE---YNKAIRNYTHFDDWYLWVQMYKGTVSMPVFQSLEA 317

  Fly   349 FAGGLFVL-----GAAETQMKHWEKYAHIGIGLTDTCHDSYWSSPTRLGPDTFAFTEESQQEIEP 408
            :..||..|     .|..|.:.::..:...| ||.:     :::.|.       .:|.|       
Mouse   318 YWPGLQSLIGDIDNAMRTFLNYYTVWKQFG-GLPE-----FYNIPQ-------GYTVE------- 362

  Fly   409 LQRNYYNLRPEVAETYLVLWRITHHPQYRLWGLEMVQAIEKYCRMPYGYTGVMDVNNVTSEPDDV 473
             :|..|.||||:.|:.:.|:|.|..|.....|.:.|::|||..::..|:..:.|:.:  .:.|:.
Mouse   363 -KREGYPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKVECGFATIKDLRD--HKLDNR 424

  Fly   474 QGSFFLGSTLKYLYLLFSDDD-------------------VVSLEQWVFNSAGHFLPI 512
            ..||||..|:|||||||..::                   ::....::||:..|  ||
Mouse   425 MESFFLAETVKYLYLLFHPNNFIHNNGSTFDSVMTPHGECILGAGGYIFNTEAH--PI 480

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
alpha-Man-IcNP_733331.1 Glyco_hydro_47 78..512 CDD:279825 119/490 (24%)
Edem2NP_663512.2 Glyco_hydro_47 42..480 CDD:307602 119/490 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 513..561
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167839756
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

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