DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alpha-Man-Ic and LOC101882461

DIOPT Version :9

Sequence 1:	NP_733331.1	Gene:	alpha-Man-Ic / 318624	FlyBaseID:	FBgn0051202	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	XP_021322719.1	Gene:	LOC101882461 / 101882461	-ID:	-	Length:	637	Species:	Danio rerio

Alignment Length:	483	Identity:	198/483 - (40%)
Similarity:	295/483 - (61%)	Gaps:	30/483 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 ESFQK-----------NIPSNDNSLKDMNPDDMRAKIKEMMMHAWRNYARVVWGTNEFRPISRRV 103
            |:|:|           ..||:..:|:      .|.|:||||..||.||....||.||.||::|..
Zfish   151 EAFKKCLLKPPIGKDQGTPSDSGTLQ------RREKVKEMMKFAWDNYKLYAWGKNELRPLTRNG 209

  Fly   104 HFGGDFATYKLGATIIESLDTLHLMGLNKELRRSRDWIEKSFHLDRVDEALSVYELTSRLLCPML 168
            |.|..|...: ||:|::|||||::|||.:|...:::|::.:..|:...|| |::|:..|.:..:|
Zfish   210 HIGNMFGGLR-GASIVDSLDTLYIMGLMEEYEEAKEWVQSNLDLNSNGEA-SLFEVNIRYVGGLL 272

  Fly   169 TLYSLTGDSLYMDKAIHIADKILPAFDTPTGIPRRLVVPKEGSTLTKY-----LSDISRTSEFGS 228
            :.:.|||..::..|.:.:.:|:||||:|||||||.::  ..||:.|.:     .:..|..:|||:
Zfish   273 SAFYLTGAEIFKQKVLELGEKLLPAFNTPTGIPRGVI--NLGSSGTSWSWGWASAGSSILAEFGT 335

  Fly   229 LHLEFYYLSEVSGYPVYRERVDAIREILAKTTRPNGLYPNAYCTKFGKWENYNCSMHRL----YD 289
            |||||.:|||:||.||:.|:|..||::|.|..:|:|||||......|.|..::.|:..|    |:
Zfish   336 LHLEFVHLSELSGNPVFTEKVMNIRKLLDKIEKPHGLYPNFLSPVSGNWVQHHVSIGGLGDSFYE 400

  Fly   290 TLLKSWIQSGRTDTQNADTFKEAMLAVAQNLVVINPEDVTYVSTFRNGTLFHRMRHSDCFAGGLF 354
            .|:||::.|.:||.:....:..||.|:..|||..:|..:|||:.:|.|.|.|:|.|..||.||:.
Zfish   401 YLIKSFLMSDKTDEEAKKMYYSAMEAIEMNLVQKSPGGLTYVAEWRGGILDHKMGHLACFCGGMI 465

  Fly   355 VLGAAETQMKHWEKYAHIGIGLTDTCHDSYWSSPTRLGPDTFAFTEESQQEIEPLQRNYYNLRPE 419
            .:||.:......:.|..:...:|.|||:||..|.|:|||:.|.|...::.....|...||.||||
Zfish   466 GIGAEDAPAGQKQHYLDLAGQITHTCHESYSRSATKLGPEAFRFDGGAEATATRLSDRYYILRPE 530

  Fly   420 VAETYLVLWRITHHPQYRLWGLEMVQAIEKYCRMPYGYTGVMDVNNVTSEPDDVQGSFFLGSTLK 484
            |.|:|:.:||:||.|:||.||.|.|:|:||:||:..|::|:.||...:...|::|.||||..|||
Zfish   531 VVESYMYMWRLTHDPKYREWGWEAVEALEKHCRVDAGFSGIRDVYASSDSHDNMQQSFFLSETLK 595

  Fly   485 YLYLLFSDDDVVSLEQWVFNSAGHFLPI 512
            |||||||:||::.||.||||:..|.|||
Zfish   596 YLYLLFSEDDLLPLEDWVFNTEAHPLPI 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ic	NP_733331.1	Glyco_hydro_47	78..512	CDD:279825	186/442 (42%)
LOC101882461	XP_021322719.1	Glyco_hydro_47	184..623	CDD:307602	186/442 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54359
OrthoDB	1	1.010	-	-		D263455at33208
OrthoFinder	1	1.000	-	-		FOG0001280
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100239
Panther	1	1.100	-	-	O	PTHR11742
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X635
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.930