Protein Alignment alpha-Man-Ic and man1b1

DIOPT Version :10

• Sequence 1: NP_733331.1
• Gene: alpha-Man-Ic / 318624
• FlyBaseID: FBgn0051202
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001120156.1
• Gene: man1b1 / 100145194
• XenbaseID: XB-GENE-5873781
• Length: 650
• Species: Xenopus tropicalis
• Alignment Length: 485
• Identity: 158/485 - (32%)
• Similarity: 254/485 - (52%)
• Gaps: 52/485 - (10%)

  Fly    57 PSNDNSLKDMNPDDMRAKIKEMMMHAWRNYARVVWGTNEFRPISRRVH--FGGDFATYKLGATII 119
            |...|..:.:..::.:..:.|...|||:.|....||.:|.:|||:...  ||       ||.|:|
 Frog   186 PPIPNEKEPVPVNERQEAVVEAFRHAWKGYTEHAWGHDELKPISKSYSEWFG-------LGLTLI 243

  Fly   120 ESLDTLHLMGLNKELRRSRDWIEKSFHLDR-VDEALSVYELTSRLLCPMLTLYSLTGDSLYMDKA 183
            ::|||:.:|||.:|..::|:|:.|....|: ||  ::::|.|.|:|..:|:.|.||.|:|::|||
 Frog   244 DALDTMWIMGLKEEFEKAREWVGKQLTFDKNVD--VNLFESTIRILGGLLSTYHLTKDALFLDKA 306

  Fly   184 IHIADKILPAFDTPTGIPRRLVVPKEGSTLTKYLSDISRTSEFGSLHLEFYYLSEVSGYPVYRER 248
            ..|..::||||:||:.:|...|....|:......:..|..:|..|:.|||..||.::|...:::.
 Frog   307 KDIGTRLLPAFNTPSKVPYSDVNIGRGTAHPPRWTSDSTVAEVTSVQLEFRELSRITGDDRFQKA 371

  Fly   249 VDAIREILAKTT-RPNGLYPNAYCTKFGKWEN-----YNCSMHRLYDTLLKSWIQSGRTDTQNAD 307
            ||.:.:.:...: :.:||.|....|..|::.:     ........|:.|||.|||||:.:....:
 Frog   372 VDQVTQHVHNLSGKRDGLVPMFINTNSGQFTHLGVFTLGARADSYYEYLLKQWIQSGKKENGFLE 436

  Fly   308 TFKEAMLAVAQNLV-VINPEDVTYVSTFRNGTLFHRMRHSDCFAGGLFVLGAAETQMKHWEKYAH 371
            .:.:|:..|.:||: ..:|..:|:|....:|....:|.|..||..|...||            ||
 Frog   437 DYMQAIEGVKKNLLRKSHPNQLTFVGELAHGHFSPKMDHLVCFLPGTLALG------------AH 489

  Fly   372 IGI---------GLTDTCHDSYWSSPTRLGPDTFAF----TEESQQEIEPLQRNYYN-LRPEVAE 422
            .||         .|.:||:..|....|.|.|:...|    .::..::|:....:.:| ||||..|
 Frog   490 NGITADHMDTAAALMETCYQMYKQMETGLSPEISHFFLSGAQKGSKDIDVKPADRHNLLRPETVE 554

  Fly   423 TYLVLWRITHHPQYRLWGLEMVQAIEKYCRMPYGYTGVMDVNNVTS----EPDDVQGSFFLGSTL 483
            :...::|.|...:|:.||.|::|:..|:.|:..|  |...:|||.|    ||.|...|||||.||
 Frog   555 SLFYMYRFTGDTKYQDWGWEILQSFNKHTRVTGG--GFTSINNVQSAGNPEPRDKMESFFLGETL 617

  Fly   484 KYLYLLFSDD-DVVSLEQWVFNSAGHFLPI 512
            |||||||||| |:::|:::|||:..|.|||
 Frog   618 KYLYLLFSDDVDLINLDKFVFNTEAHPLPI 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ic	NP_733331.1	Glyco_hydro_47	78..512	CDD:460241	153/462 (33%)
man1b1	NP_001120156.1	rne	<139..207	CDD:236766	2/20 (10%)
		Glyco_hydro_47	207..647	CDD:460241	153/462 (33%)