Protein Alignment GluRIIE and GLR2.5

DIOPT Version :10

• Sequence 1: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_001332219.1
• Gene: GLR2.5 / 830991
• AraportID: AT5G11210
• Length: 918
• Species: Arabidopsis thaliana
• Alignment Length: 925
• Identity: 197/925 - (21%)
• Similarity: 370/925 - (40%)
• Gaps: 170/925 - (18%)

  Fly     3 FNH----FVILWSL-FSIHISVNWAQYENFGGYDNYQSLESVPIGLLTDQNTEQMNIVFDHAIDV 62
            |:|    |:.||.| |.:.:.::.       |....::|: |.:|::...|....::.. .||::
plant     4 FHHLVSRFLSLWLLIFLVFLVLSL-------GKSQKEALQ-VKVGIVLGSNVTLADLSL-RAINM 59

  Fly    63 ANQEVGTSLTSLKEEV--NYGDAYQSY-----GKLCRMLETGIAGVFGPSSRHTAVHLMSICDAM 120
            :..|...:....|..:  |..|:.|:.     ..|..:.:..:..:.||.:...|..|:::.:..
plant    60 SLSEFYNTHNGFKTRIVLNVRDSKQTVVGAAASALYLIKKREVVAIIGPGTSMQAPFLINLGNQS 124

  Fly   121 DIPHI-YSYMSENAEGFNLHPH-------PADLAKALYSLITEFNWTRFIFLYESAEY-LNILNE 176
            .:|.| :|..|...:... .|:       .:...:|:.::|..|.|...:.:|...|: ..||..
plant   125 KVPIISFSATSPLLDSLR-SPYFIRATHDDSSQVQAISAIIESFRWREVVPIYVDNEFGEGILPN 188

  Fly   177 LTTMLGKSGTVITV-LRYDMQLNGNYK--QVLRRVRK--SVDNRIVVVGSSETMPE----FLNQA 232
            |.....:    |.| :||...::.:|.  |:.:.:.|  ::..|:.:|   ..:|:    ..:.|
plant   189 LVDAFQE----INVRIRYRSAISLHYSDDQIKKELYKLMTMPTRVFIV---HMLPDLGSRLFSIA 246

  Fly   233 QQVGIINEDYKYIIGN--LDFHSFDLEEYKYSEANITGLRLFSPEKMAVKELL-------MKLGY 288
            :::.::::.|.:|:.|  .|..|...|....:...:.|::.:..:.   ||||       .:.|
plant   247 KEIDMLSKGYVWIVTNGIADLMSIMGESSLVNMHGVLGVKTYFAKS---KELLHLEARWQKRFG- 307

  Fly   289 PTDQDEFRNGSCPITVEMALTYDAVQLFAQTLKNLPFKPMPQNCSQRTESVRDDGSSFKNYMRTL 353
               .:|..|.:|       ..|||....|.:::.:....|..|.::...|..|.|:........|
plant   308 ---GEELNNFAC-------WAYDAATALAMSVEEIRHVNMSFNTTKEDTSRDDIGTDLDELGVAL 362

  Fly   354 ---RLTDRLLTGPIYFEG-----NVRKG----YHLDVIELQPSGIVKVGTWDE----------DR 396
               :|.|.|.|  :.|:|     .::.|    ....:|.::.||...||.|..          |:
plant   363 SGPKLLDALST--VSFKGVAGRFQLKNGKLEATTFKIINIEESGERTVGFWKSKVGLVKSLRVDK 425

  Fly   397 -QYRPQRLAPTTAQFDSVDNSLANKTFI------------ILLSVPNKP-YAQLVETYKQLEGN- 446
             .:..:||.|.....|::        |:            :.::||.|. :...||..|....|
plant   426 VSHSSRRLRPIIWPGDTI--------FVPKGWEFPTNAKKLRIAVPKKDGFNNFVEVTKDENTNV 482

  Fly   447 SQYEGYGVDLIKELADKLGFNFTF------VNGGNDYGSYNKSTNESTGMLREIMTGRADLAITD 505
            ....|:.:|:...:..::.:..::      ...|...|||::       |:..:..|..|.|:.|
plant   483 PTVTGFCIDVFNTVMSQMPYAVSYEYIPFDTPDGKPRGSYDE-------MVYNVFLGEFDGAVGD 540

  Fly   506 LTITSEREQALDFTIPFMNLGIAILYLKPQKATPEL--FTFMDPFSEEVWWFLGFSFLGVSLSFF 568
            .||.:.|...:||.:|:...|  |::|.|.|...|.  :.|:.|.::|:|.....|||.:.:..:
plant   541 TTILANRSHYVDFALPYSETG--IVFLVPVKDGKEKGEWVFLKPLTKELWLVTAASFLYIGIMVW 603

  Fly   569 ILGRLSPSEWDNPYPCIEEPEELENQFTLG--NSIWFTTGALLQQGSEIGPKALSTRTVASFWWF 631
            |.      |:       :..||...|..:.  :|:::.:.:.|........::..||.:...|.|
plant   604 IF------EY-------QADEEFREQMIIDKISSVFYFSFSTLFFAHRRPSESFFTRVLVVVWCF 655

  Fly   632 FTLIVVSSYTANLAAFLTIEKPQSLINSVDDLADNKDGVVYGAKKTGS---TRNFFMTSAEERYK 693
            ..||:..||||.|.:.||:::.:..:..:|||  .|.||..| .:|||   .|...|...|.|.|
plant   656 VLLILTQSYTATLTSMLTVQELRPTVRHMDDL--RKSGVNIG-YQTGSFTFERLKQMRFDESRLK 717

  Fly   694 KMNKFMSENPQYLTEDNMEGVNRVKTNTHYAFL-MESTSIEYNTKRECNLKKIGDALDEKGYGIA 757
            ..|........:|.:.:..|::.......|..| |.....||:.        |.......|:|.|
plant   718 TYNSPEEMRELFLHKSSNGGIDAAFDEVAYIKLFMAKYCSEYSI--------IEPTFKADGFGFA 774

  Fly   758 MRKDWPHRGKFNNALLELQEQGVLEKMKNKWWNEVGTGIC--ATKEDAPDATPLDMNNLEGVFFV 820
            .....|.....:..:|.:.|...::.::|||:  :|...|  :|..|:|  ..||.::.|.:|.:
plant   775 FPLGSPLVSDISRQILNITEGDAMKAIENKWF--LGEKHCLDSTTSDSP--IQLDHHSFEALFLI 835

  Fly   821 LLVGSCCALLYGIIS 835
            :.|.|...||..:.|
plant   836 VFVVSVILLLLMLAS 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	40..402	CDD:380605	78/418 (19%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	91/398 (23%)
		Lig_chan	551..824	CDD:459656	67/280 (24%)
GLR2.5	NP_001332219.1	PBP1_GABAb_receptor_plant	38..421	CDD:380645	77/407 (19%)
		GluR_Plant	456..806	CDD:270404	89/382 (23%)
		Lig_chan	584..838	CDD:459656	67/281 (24%)