Protein Alignment GluRIIE and GLR2.6

DIOPT Version :10

• Sequence 1: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_001330285.1
• Gene: GLR2.6 / 830988
• AraportID: AT5G11180
• Length: 967
• Species: Arabidopsis thaliana
• Alignment Length: 947
• Identity: 180/947 - (19%)
• Similarity: 346/947 - (36%)
• Gaps: 220/947 - (23%)

  Fly     3 FNHFVI----LWSLFSIHISVNWAQYENFGGYDNYQSLESVPIGLLTDQNTEQMNIVFDHAIDVA 63
            |||.:.    ||.||.|:..|...:        :.|.:..|.:|::.|.|.....:.. .||:::
plant     4 FNHLLSRALPLWLLFFINFLVLLGK--------SQQEVLQVQVGIVLDTNATLAALSL-RAINMS 59

  Fly    64 NQEVGTSLTSLKEEV--NYGDAYQSY-----GKLCRMLETGIAGVFGPSSRHTAVHLMSICDAMD 121
            ..|...:....|..:  |..|:.::.     ..|..:.:..:..:.||.:...|..|:::.:...
plant    60 LSEFYNTHNGFKTRIVLNIRDSKRTVVGAAASALYLIKKREVVAIIGPGNSMQAPFLINLGNQSQ 124

  Fly   122 IPHI---------------YSYMSENAEGFNLHPHPADLAKALYSLITEFNWTRFIFLYESAEY- 170
            :|.|               |...:.:.:...:|        |:.::|..|.|...:.:|...|:
plant   125 VPIISFSASSPVLDSLRSPYFIRATHDDSSQVH--------AISAIIESFRWREVVPIYADNEFG 181

  Fly   171 -------LNILNELTTMLGKSGTVITVLRYDMQLNGNYKQVLRRVRKSVDNRIVVVGSSETMPEF 228
                   ::...|:...:.....:......|:.....||.:....|..:.:.:..:||     ..
plant   182 EGILPYLVDAFQEINVRIRYRSAISVHSTDDLVKKELYKLMTMPTRVFIVHMLPDLGS-----RL 241

  Fly   229 LNQAQQVGIINEDYKYIIGN--LDFHSFDLEEYKYSEANITGLRLFSPEKMAVKELL-------M 284
            .:.|:::|::.:.|.:|:.|  .|..|...|....:...:.|::.:....   |||:       .
plant   242 FSIAKEIGMMTKGYVWIVTNGIADQMSVMGESSLENMHGVLGVKTYFSRS---KELMYLETRWRK 303

  Fly   285 KLGYPTDQDEFRNGSCPITVEMALTYDAVQLFAQTLK------NLPFKPMPQNCSQRTESVRDDG 343
            :.|    .:|..|..|       ..||.....|.:::      |:.|....:|.|:.......|.
plant   304 RFG----GEELNNFEC-------WGYDTATALAMSIEEISSNVNMSFSQTKRNTSRDDTGTDLDD 357

  Fly   344 SSFKNYMRTLRLTDRLLTGP--------IYFEG-----NVRKG----YHLDVIELQPSGIVKVGT 391
            .||            .|:||        :.|:|     .::.|    ....::.::.||...||.
plant   358 LSF------------ALSGPKLLQALATVSFKGVAGRFQLKNGKLEATTFKIVNIEESGERTVGF 410

  Fly   392 WDE---------------DRQYRPQRLAPTTAQFDSVDNSLANKTFI------------ILLSVP 429
            |..               ...:...||.|.....|::        |:            :.::||
plant   411 WKSKVGLVKSLRVNQTGIKISHSSHRLRPIIWPGDTI--------FVPKGWEFPTNAKKLRIAVP 467

  Fly   430 NKP-YAQLVETYKQLEGNS-QYEGYGVDLIKELADKLGFNFTF------VNGGNDYGSYNKSTNE 486
            .|. :...||..|....|: ...|:.:|:......::.:...:      ...|...|||::
plant   468 KKDGFNNFVEVTKDANTNAPTITGFCIDVFDTAMRQMPYAVPYEYIPFETPDGKPRGSYDE---- 528

  Fly   487 STGMLREIMTGRADLAITDLTITSEREQALDFTIPFMNLGIAILYLKPQKATPELFTFMDPFSEE 551
               |:..:..|..|.|:.|.||.:.|...:||.:|:...||.::.....:.....:.|:.|.:.|
plant   529 ---MVYHVFLGEFDGAVGDTTILANRSTYVDFALPYSETGIVVVVPVKDEREKGKWVFLKPLTRE 590

  Fly   552 VWWFLGFSFLGVSLSFFILGRLSPSEWDNPYPCIEEPEELENQFTLGNSIWFTTGALL---QQGS 613
            :|:....|||.:.:..:|....:..::        ..:.:.|:  :.|..:|:...|.   .:.|
plant   591 LWFLTAASFLYIGIMVWIFEYQASGDF--------RKQSIINK--ISNVFYFSFSTLFFAHMRPS 645

  Fly   614 EIGPKALSTRTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLADNKDGVVYGAKKTG 678
            |    ::.||.:...|.|..||:..||||.|.:.||:::.:..:..:|||.::...:.|   :||
plant   646 E----SIFTRVLVVVWCFVLLILTQSYTATLTSMLTVQELRPTVRHMDDLRNSGVNIGY---QTG 703

  Fly   679 STRNFFMTSAEERYKKMNKFMSENPQYLTEDNMEGVNRVKTNTHYAFLMESTS------------ 731
            |       ...||.|:|....|....|.|...|          |..||.:|::
plant   704 S-------FTFERLKQMGYKESRLKTYDTPQEM----------HELFLKKSSNGGIDAAFDEVAY 751

  Fly   732 IEYNTKRECNLKKIGD-ALDEKGYGIAMRKDWPHRGKFNNALLELQEQGVLEKMKNKWWNEVGTG 795
            ::....:.|:...|.: .....|:|.|.....|.....:..:|.:.|...::.::|||.  :|..
plant   752 VKLFMAKYCSKYTIIEPTFKADGFGFAFPLGSPLVPDLSRQILNITEGETMKAIENKWL--LGEK 814

  Fly   796 IC--ATKEDAPDATPLDMNNLEGVFFVLLVGSCCALL 830
            .|  :|..|:|  ..||.::.|.:|.::.|.|...||
plant   815 HCLDSTTSDSP--IRLDHHSFEALFTIVFVVSMLLLL 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	40..402	CDD:380605	68/438 (16%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	84/406 (21%)
		Lig_chan	551..824	CDD:459656	64/290 (22%)
GLR2.6	NP_001330285.1	PBP1_GABAb_receptor_plant	38..421	CDD:380645	68/422 (16%)
		GluR_Plant	460..810	CDD:270404	82/390 (21%)
		Lig_chan	590..842	CDD:459656	64/289 (22%)