Protein Alignment GluRIIE and GLUR2

DIOPT Version :10

• Sequence 1: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_567981.1
• Gene: GLUR2 / 829682
• AraportID: AT4G35290
• Length: 912
• Species: Arabidopsis thaliana
• Alignment Length: 886
• Identity: 192/886 - (21%)
• Similarity: 355/886 - (40%)
• Gaps: 163/886 - (18%)

  Fly    39 VPIGLLTDQNTEQMNIVFDHAIDVANQEVGTS---LTSLKEEVNYGDAYQS-----YGKLCRMLE 95
            |.:|.:....|.|..:. :.|:..|.::|.:.   |...|..:...||.::     .|.| :.:|
plant    30 VDVGAIFSLGTLQGEVT-NIAMKAAEEDVNSDPSFLGGSKLRITTYDAKRNGFLTIMGAL-QFME 92

  Fly    96 TGIAGVFGPSSRHTAVHLMSICDAMDIPHI-YSYMSENAEG----FNLHPHPAD--LAKALYSLI 153
            |....:.||.:...|..|..:.:.:.:|.: ::.:..:...    |.:...|:|  |.:|:..:|
plant    93 TDAVAIIGPQTSIMAHVLSHLANELSVPMLSFTALDPSLSALQFPFFVQTAPSDLFLMRAIAEMI 157

  Fly   154 TEFNWTRFIFLYESAEYLNILNELTTMLGKSGTVITVLRYDMQLNG-----NYKQVL-------- 205
            :.:.|:..|.||...:  |..|.:|. ||.            :|.|     :||.||
plant   158 SYYGWSEVIALYNDDD--NSRNGITA-LGD------------ELEGRRCKISYKAVLPLDVVITS 207

  Fly   206 -RRV------RKSVDNRIVVVGS-SETMPEFLNQAQQVGIINEDYKYIIGN-----LDFHSFDLE 257
             |.:      .:.:::|:::|.: .:|..:...:||::|::.:.|.:|...     ||  |.:..
plant   208 PREIINELVKIQGMESRVIIVNTFPKTGKKIFEEAQKLGMMEKGYVWIATTWLTSLLD--SVNPL 270

  Fly   258 EYKYSEA--NITGLRLFSPEKMAVKELLMKLGYPTDQDEFRNGSCPITVEMALTYDAVQLFAQTL 320
            ..|.:|:  .:..||:.:|.....|:.:.:      .::..||:..:.|.....||.|.:.|:.:
plant   271 PAKTAESLRGVLTLRIHTPNSKKKKDFVAR------WNKLSNGTVGLNVYGLYAYDTVWIIARAV 329

  Fly   321 K-------NLPFKPMPQNCSQR--------TESVRDDGSSFKNYMRTLRLTDRLLTGPIYF---E 367
            |       |:.|...|:..|.:        ..|:.|.||.|.:|:....:|.  :||.|.|   .
plant   330 KRLLDSRANISFSSDPKLTSMKGGGSLNLGALSIFDQGSQFLDYIVNTNMTG--VTGQIQFLPDR 392

  Fly   368 GNVRKGYHLDVIELQPSGIVKVGTWDEDRQYR---PQRLAPTTAQFDSVDNSLANKTF------- 422
            ..::..|  |:|.:...|..::|.|.......   |:.|....:...|.:..|.|.|:
plant   393 SMIQPSY--DIINVVDDGFRQIGYWSNHSGLSIIPPESLYKKLSNRSSSNQHLNNVTWPGGTSET 455

  Fly   423 -----------IILLSVPNKPYAQLVETYKQLEGNSQYEGYGVDL----IKELADKLGFNFTFVN 472
                       .:.:.||::  |...|...:|:|:::.:||.:|:    :|.::..:...|....
plant   456 PRGWVFPNNGRRLRIGVPDR--ASFKEFVSRLDGSNKVQGYAIDVFEAAVKLISYPVPHEFVLFG 518

  Fly   473 GGNDYGSYNKSTNESTGMLREIMTGRADLAITDLTITSEREQALDFTIPFMNLGIAILY-LKPQK 536
            .|....::|:..|..|       .|..|..:.|:.|.::|.:.:|||.|::..|:.::. :....
plant   519 DGLKNPNFNEFVNNVT-------IGVFDAVVGDIAIVTKRTRIVDFTQPYIESGLVVVAPVTKLN 576

  Fly   537 ATPELFTFMDPFSEEVWWFLGFSFLGVSLSFFILGRLSPSEWDNPYPCIEEPEELENQFTLGNSI 601
            .||  :.|:.||:..:|......||.|....:||......|:..|      |.:     .:...:
plant   577 DTP--WAFLRPFTPPMWAVTAAFFLIVGSVIWILEHRINDEFRGP------PRK-----QIVTIL 628

  Fly   602 WFTTGALLQQGSEIGPKALST--RTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLA 664
            ||:...:.....|   ..:||  |.|...|.|..||:.|||||:|.:.||:::..|.|..||.|.
plant   629 WFSFSTMFFSHRE---NTVSTLGRAVLLIWLFVVLIITSSYTASLTSILTVQQLNSPIRGVDTLI 690

  Fly   665 DNKDGVVYGAKKTGSTRNFFMTS----AEERYKKMNKFMSENPQYLTEDNMEGVNRVKTNTHYAF 725
            .:...|.:   :.||....:|..    |..|...:.     :|:       |....::..|..|.
plant   691 SSSGRVGF---QVGSYAENYMIDELNIARSRLVPLG-----SPK-------EYAAALQNGTVAAI 740

  Fly   726 LMESTSIEYNTKRECNLKKIGDALDEKGYGIAMRKDWPHRGKFNNALLELQEQGVLEKMKNKWWN 790
            :.|...::......|.....|......|:|.|..:|.|.....:.|:|.|.|.|.|:|:.:||.:
plant   741 VDERPYVDLFLSEFCGFAIRGQEFTRSGWGFAFPRDSPLAIDMSTAILGLSETGQLQKIHDKWLS 805

  Fly   791 EVGTGICATKEDAPDATPLDMNNLEGVFFVLLVGSCCALLY 831
            ..............|:..|.:.:..|:|.|..: ||...|:
plant   806 RSNCSNLNGSVSDEDSEQLKLRSFWGLFLVCGI-SCFIALF 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	40..402	CDD:380605	88/425 (21%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	92/399 (23%)
		Lig_chan	551..824	CDD:459656	65/278 (23%)
GLUR2	NP_567981.1	PBP1_GABAb_receptor_plant	31..422	CDD:380645	87/419 (21%)
		GluR_Plant	466..804	CDD:270404	89/377 (24%)
		Lig_chan	587..838	CDD:459656	65/279 (23%)