Protein Alignment GluRIIE and GLR1.4

DIOPT Version :10

• Sequence 1: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_187408.2
• Gene: GLR1.4 / 819940
• AraportID: AT3G07520
• Length: 861
• Species: Arabidopsis thaliana
• Alignment Length: 942
• Identity: 194/942 - (20%)
• Similarity: 365/942 - (38%)
• Gaps: 200/942 - (21%)

  Fly    31 DNYQSL----ESVPIGLLTDQNTEQMNIV----------FDHAIDVANQEVGTSLTSLKEEVNYG 81
            ||...|    |.|.|||:.|..:.:..:|          |.|    .|....|.::.|..: ::|
plant    34 DNVDRLPVVYEDVRIGLVVDMGSMEGKLVTTSISMALSDFYH----VNNGYRTRVSVLSRD-SHG 93

  Fly    82 DAYQSYGKLCRMLET-GIAGVFGPSSRHTAVHLMSICDAMDIPHIYSYM---SENAEGFN----- 137
            |..|:......:|:| .:..:.|..|...|.:|..:.:...:|.|.|:.   |.:...:|
plant    94 DPLQALAAAMDLLQTEQVEALVGGQSLLEAKNLAELGEKTKVPVISSFQVPSSLSLAKYNYFIQA 158

  Fly   138 LHPHPADLAKALYSLITEFNWTRFIFLYESAEYLNILNELTTMLG--KSGTVITVLRYDMQLNGN 200
            .|...:: ||.:.:|.:.|:|...:.:||..:  :....:..::|  :...:....:.:..::.|
plant   159 THDTSSE-AKGIAALFSNFDWRTAVLIYEDDD--DWRESIQPLVGHFQQNAIHIEYKAEFSVSSN 220

  Fly   201 YKQVLRRVR--KSVDNRIVVVGSSETMPEFLNQ-AQQVGIINEDYKYIIGNLDFHSFDLEEY--K 260
            .:.:::::|  |:...||.|...||.:...|.. |:::|::.|.|.:|:.....::|....|  |
plant   221 EECIMKQLRKFKASGIRIFVAHISERIANRLFPCARRLGMMEEGYAWILTARSMNNFQDTNYLAK 285

  Fly   261 YSEANITGLRLFSP--EKMAVKELLMKLGYPTDQDEFRNGSCPITV-----EMALTYDAVQLFAQ 318
            .....:.|.:.:.|  |::....|..|.....::...|...|.|..     .:|...:..:|...
plant   286 EEMEGVIGFKSYIPLTEELHNFTLRWKRSLRLEEVVTRMSVCSIWAHDIAWSLARAAEVAKLPGL 350

  Fly   319 TLKNLPFKPMPQNCSQRTESVRDDGSSFKNYMRTLRLTDRLLTGPIYFEGNVRKGYHLDVIELQP 383
            ::.:| .:.:|       ||.:..|                |:|.|.|..........:::.:..
plant   351 SVYDL-LEAIP-------ESAKHKG----------------LSGDIKFIDKKFISDKFEIVNMIG 391

  Fly   384 SGIVKVGTWDEDR--QYRPQRLAPTTA--------------QFDSVDNSLANKTFIILLSVP-NK 431
            .|...||.|:...  ..|.:||:.|.|              :..|:......|...:.:.|| ..
plant   392 RGERSVGLWNSGSFISNRRRRLSSTKALETIIWPGGSTRIPKIRSLKEKRHGKKKKLRVLVPAGN 456

  Fly   432 PYAQLVETYKQLE-GNSQYEGYGVDLIKELADKLGFNFTFV----NGGNDYGSYNKSTNESTGML 491
            ...|::|.....: |.:...||.:|:.:  ...|.||:...    .|..:|.:||       .::
plant   457 ITPQILEVKTDFKTGVTAATGYCIDVFE--TSILPFNYEVEYIPWPGAINYKNYN-------DLV 512

  Fly   492 REIMT--GRADLAITDLTITSEREQALDFTIPFMNLGIAILYLKPQKATPELFTFMDPFSEEVWW 554
            ..:.:  .:.|.|:.|:|||..|...:|||:||.::|:|::..|.:    .::....|.:..:|.
plant   513 YTLYSQKDKYDAAVGDITITDNRSLYVDFTLPFTDMGLAVVTAKDK----SMWIIFKPLTLSLWL 573

  Fly   555 FLGFSFLGVSLSFFIL-GRLSPSEWDNPYPCIEEPEELENQFT----LGNSIWFTTGALLQQGSE 614
            .:.        ||||| |.:   .|     .||..:..:.|.:    :|..:.|....|:....|
plant   574 TIA--------SFFILTGAI---VW-----LIERHDNADFQGSCFQQIGTLLCFGFSTLVFAHRE 622

  Fly   615 IGPKALSTRTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLADNKDGVVYGAKKTGS 679
            .....:| |.|...|.|..||:.|:|||.|.:.:|:::       :..|..|::...:.|....:
plant   623 RLQHNMS-RFVVIVWIFAVLILTSNYTATLTSVMTVQQ-------IRGLKSNENIGFFSASIAAN 679

  Fly   680 TRNFFMTSAEERYKKMNKFMSENPQYLTEDNMEGVNRVKTNTHYAFLME-------------STS 731
            ..|...|....|||.:.          |.|:.  .|.::..| .:|:::             |..
plant   680 VVNDNPTFQGPRYKGLK----------TADDF--TNALRNGT-ISFIVDEVPYVKLFVAKHPSEF 731

  Fly   732 IEYNTKRECNLKKIGDALDEKGYGIAMRKDWPHRGKFNNALLELQEQGVLEKMKNKWWNEVGTGI 796
            :...|:...|           |:|.|.:|..|...|.:..:.:|:....|:.::|.|:....|.
plant   732 VIVETESVTN-----------GFGFAFQKGSPLVQKVSREIEKLRRTEKLKAIENWWFQRQTTS- 784

  Fly   797 CATKEDAPDATPLDMNNLEGVFFVLLVGSCCALLYGIISWVLFVMKKAHHYRVPLRDALKEEFQF 861
             ||.||.  ..||.:....|:|.:..|....||:..:|.|                  .:|:.|.
plant   785 -ATSEDT--FHPLTVYTFRGLFMITGVSFAFALIVYLIPW------------------NREQRQV 828

  Fly   862 VI-DFNNYV-----RVLKNSASIYSRSRQSSM 887
            |: .|:.||     |.::.|.:..:|..::|:
plant   829 VLKHFHRYVSHRFAREIRPSPTTPNRQNENSV 860

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	40..402	CDD:380605	74/396 (19%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	86/396 (22%)
		Lig_chan	551..824	CDD:459656	63/290 (22%)
GLR1.4	NP_187408.2	PBP1_GABAb_receptor_plant	47..410	CDD:380645	73/394 (19%)
		GluR_Plant	448..778	CDD:270404	84/390 (22%)
		Periplasmic_Binding_Protein_Type_2	476..>657	CDD:473866	53/210 (25%)