Protein Alignment GluRIIE and GLR5

DIOPT Version :10

• Sequence 1: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_565744.1
• Gene: GLR5 / 817801
• AraportID: AT2G32400
• Length: 921
• Species: Arabidopsis thaliana
• Alignment Length: 973
• Identity: 202/973 - (20%)
• Similarity: 377/973 - (38%)
• Gaps: 212/973 - (21%)

  Fly    47 QNTEQMNI----VFDH--------AIDVANQEVGTSLTSLKE-------EVNYGDAYQ-SYGKLC 91
            |..:.:||    .||.        |::.|..:|....:.|||       |.:..:.:: |:|..
plant    26 QRPQLVNIGAVFAFDSVIGRAAKVALEAAVSDVNNDKSFLKETELRLLMEDSACNVFRGSFGAF- 89

  Fly    92 RMLETGIAGVFGPSSRHTAVHLMSICDAMDIPHIYSYMSENAEGFNLH--------PHPADLAKA 148
            .:||..:..:.||.|...|..:..|...:..| :.|:.:.:.....|.        |:.|....|
plant    90 ELLEKEVVAMIGPISSSVAHTISDIAKGLHFP-LVSFAATDPTLSALQFPFFLRTTPNDAHQMSA 153

  Fly   149 LYSLITEFNWTRFIFLYESAEYLNILNELTTMLGKSGTVITVLRYDMQLNGNYKQVLRRV----- 208
            |..||..:.|...|.:|...|           ||::|    |...|.:|.....::..:|
plant   154 LVDLINFYGWKEVISVYSDDE-----------LGRNG----VSALDDELYKKRSRISYKVPLSVH 203

  Fly   209 ------------RKSVDNRIVVVG-SSETMPEFLNQAQQVGIINEDYKYIIGNLDFHSFDLEE-- 258
                        .||:..|:.::. ..:.:....:.||::.::..:|.::.  .|:.|..|:.
plant   204 SDEKFLTNALNKSKSIGPRVYILHFGPDPLLRIFDIAQKLQMMTHEYVWLA--TDWLSVTLDSLS 266

  Fly   259 ----YKYSEANITGLRLFSPEKMAVKELLMKLGYPTDQDEFRNGSCPITVEMAL-TYDAVQLFAQ 318
                .|..| .:.|||...||.:.::....||......:.:           || .||.|.:.|.
plant   267 DKGTLKRLE-GVVGLRQHIPESVKMEHFTHKLQSNRSMNAY-----------ALHAYDTVWMIAH 319

  Fly   319 TLK-------NLPFKPMPQNCSQRTESVRDDGSSFKN-----YMRTLRLTDRLLTGPIYFEGNVR 371
            .::       |:.|....:....|...:..:...|.|     ..:.|::....:.|.:.| |:.|
plant   320 GIEELLNEGINITFSYSEKLLHARGTKLHLEKIKFFNSGELLLEKLLKVNFTGIAGQVQF-GSGR 383

  Fly   372 K--GYHLDVIELQPSGIVKVGTWDEDRQYRPQRLAPTT------AQFDSVDNSLANKTF------ 422
            .  |...::|.:..:.:..||.|.::..:  ..:||.|      ..|.| |..|.:.|:
plant   384 NVIGCDYEIINVNKTDVHTVGFWSKNGGF--SVVAPKTRHSQKKTSFVS-DEKLGDITWPGGGRE 445

  Fly   423 ------------IILLSVPNKPYAQLVETYKQLEGNSQY--EGYGVDLIKELADKLGFN--FTFV 471
                        .:.:.||.:  ...||...: |.||.:  :|:.:|:..|....:.::  :.|.
plant   446 KPRGWVIADSADPLKIVVPRR--VSFVEFVTE-EKNSSHRIQGFCIDVFIEALKFVPYSVPYIFE 507

  Fly   472 NGGNDYGS--YNKSTNESTGMLREIMTGRADLAITDLTITSEREQALDFTIPFMNLGIAILYLKP 534
            ..||.:.|  ||.       :::.:..|..|.|:.|:.|...|.:.:||:.|:.:.|:.::.  |
plant   508 PFGNGHSSPNYNH-------LIQMVTDGVYDAAVGDIAIVPSRSKLVDFSQPYASTGLVVVI--P 563

  Fly   535 QKATPELFTFMDPFSEEVWWFLGFSFLGVSLSFFILGRLSPSEWDNPYPCIEEPEELENQFTLGN 599
            .......:.|:.||:..:|..:..|||.:::..:||......::..|      |..     .|..
plant   564 ANDDNATWIFLRPFTSRLWCVVLVSFLVIAVVIWILEHRINEDFRGP------PRR-----QLST 617

  Fly   600 SIWFTTGALLQQGSEIGPKALSTRTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLA 664
            .:.|:...|.::..|.....|: |.|...|.|..:::.:||||||.:.||:::..|.|..:|.|.
plant   618 MLLFSFSTLFKRNQEDTISNLA-RLVMIVWLFLLMVLTASYTANLTSILTVQQLPSAITGIDSLR 681

  Fly   665 DNKDGVVYGA---------KKTGSTRNFFM-TSAEERYKKMNKFMSENPQYLTEDNMEGVNRVKT 719
            .::..:.|.|         ...|..|:..: ..:.|.|:|..|        |...|..||..:..
plant   682 ASEVPIGYQAGTFTLEYLTYSLGMARSRLVPLDSTEEYEKALK--------LGPTNWGGVAAIVD 738

  Fly   720 NTHY--AFLMESTSIEYNTKRECNLKKIGDALDEKGYGIAMRKDWPHRGKFNNALLELQEQGVLE 782
            ...|  .||.|.|          ..|.:|:....:|:|.|.::|.|.....:.|:|:|.|...|:
plant   739 ELPYIELFLAERT----------GFKIVGEPFMHRGWGFAFKRDSPLAIDMSTAILKLSETRKLQ 793

  Fly   783 KMKNKWWNEVGTGICATKED-APDATPLDMNNLEGVFFVLLVGSCCALLYGIISWVLFVMKKAHH 846
            :::.||..:..   ||.|.: .|:...|.:.:.:|::.|.:..:..|.|.    :||.::::...
plant   794 EIRKKWLCKTN---CAGKSNWNPEPNQLHLKSFKGLYLVCIAITVSAFLV----FVLRMIRQFVR 851

  Fly   847 YRVPLRDA--------------LKEEFQFVIDFNNYVRVLKNSAS-IYSRSRQSSMSVASVAQ 894
            ||...|.:              |:|   .|.||..:|...:.:.. ::.||..|:.:.:.|.:
plant   852 YRRMERTSSMPRASWSASPTLRLRE---LVFDFVEFVDEKEEAIKRMFRRSDDSNNNPSHVGE 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	40..402	CDD:380605	80/421 (19%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	91/406 (22%)
		Lig_chan	551..824	CDD:459656	67/285 (24%)
GLR5	NP_565744.1	PBP1_GABAb_receptor_plant	32..416	CDD:380645	79/417 (19%)
		GluR_Plant	458..800	CDD:270404	89/383 (23%)
		Lig_chan	578..832	CDD:459656	67/286 (23%)