Protein Alignment GluRIIE and Ir84a

DIOPT Version :9

• Sequence 1: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 747
• Identity: 146/747 - (19%)
• Similarity: 260/747 - (34%)
• Gaps: 187/747 - (25%)

  Fly   159 TRFIFLYESAEYLNI--LNELTTMLGKSGTVITVLRYDMQLNGNYKQVLRRVRKSVD-NRIVVVG 220
            |.|:.|....::|..  |:.:..:.|........:....:|..||:....|...|.: ..::..|
  Fly    30 TNFLELAAFEDFLRSEHLSHVLVVRGDDADGDWKIECHQKLLANYRVQFYRPEMSANFEDLMFYG 94

  Fly   221 SSETMPEFLNQ------------AQQVGIINEDYK-YIIGNLDFHSFDLEEYKYSEANITGLRLF 272
            |..|....||.            |.:.|..|.... :|:|:
  Fly    95 SPRTAVLVLNSEHVLVRRQVFGVASEAGYFNNSLAWFILGS------------------------ 135

  Fly   273 SPEKMAVKELLMKL--GYPTDQDEFRNGSCPITVEM-------ALTYDAVQLFAQTLKNLPFKPM 328
            ..|.:.|::|:.:|  ||....|      ..|||.:       .|.||..::..|.  |.|....
  Fly   136 GRESLPVEQLIDQLLSGYRMGID------ADITVALRGPDNASMLFYDVYRISRQA--NTPLIIE 192

  Fly   329 PQNCSQRTESVRDDGSSFKN--YMRTLRLTDRLLTGPIYFEGNVRKGYHLDVIELQPSGIVKVGT 391
            .:.....:...:..| :|||  .:|.....:..|.|.             .|:..:|.|...:..
  Fly   193 KKGLWTHSGGYQKFG-NFKNTWVIRRRNFLNVTLIGS-------------TVLTEKPPGFGDMEY 243

  Fly   392 WDEDRQYRPQRLAPTTAQFDSVDNSLANKTFIILLSVPNKPYAQLVETYKQLEGNSQYEGYGVDL 456
            ..:|:|.  |:|.|           :..||:.:.         ||||..           :.:.|
  Fly   244 LADDKQL--QQLDP-----------MQRKTYQLF---------QLVERM-----------FNLSL 275

  Fly   457 IKELADKLGFNFTFVNGGNDYGSYNKSTNESTGMLREIMTGRADLAITDLTITSEREQALDFTIP 521
            ...|.||.|...       |.||:       :|::.::.:..||.|:..:....:|:..:.::..
  Fly   276 AISLTDKWGELL-------DNGSW-------SGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAV 326

  Fly   522 FMNLGIAILYLKPQKATPELFTFMDPFSEEVWWFLGFSFLGVSLSFFILGRLSPSEWDNPYPCIE 586
            .....|..|:..|:::..:.. |.:|.|.:|||.:.....|.::......||.           .
  Fly   327 LHTQNIHFLFRHPRRSHIKNI-FFEPLSNQVWWCVLALVTGSTILLLFHVRLE-----------R 379

  Fly   587 EPEELENQFTLGNSIWFT-TGALLQQG--SEIGPKALSTRTVASFWWFFTLIVVSSYTANLAAFL 648
            ....:||:|:.   :||| ....||||  :||. :..|||.:.|....|:.:::..|.|.:...|
  Fly   380 MLSNMENRFSF---VWFTMLETYLQQGPANEIF-RLFSTRLLISLSCIFSFMLMQFYGAFIVGSL 440

  Fly   649 TIEKPQSLINSV----DDLADNKDGVVYGAKKTGSTRNFFMTSAEERYKKMNKFMSENPQYLTED 709
            ..|..:|::|..    .:||...:.:.|......:|.|..:  .:...||:.|....|...|
  Fly   441 LSESARSIVNLQALYDSNLAIGMENISYNFPIFTNTSNQLV--RDVYVKKICKSGEHNIMSL--- 500

  Fly   710 NMEGVNRV---------KTNTHYAFLMESTSIEYNTKRECNLKKIGDALDEKGYGIAMRKDWPHR 765
             .:|..|:         ..:..|..|:|   ::.:....|:|:::...|.... |..|.|..|.|
  Fly   501 -QQGAERIIQGRFAFHTAIDRMYRLLLE---LQMDEAEFCDLQEVMFNLPYDS-GSVMPKGSPWR 560

  Fly   766 GKFNNALLELQEQGVLEKMKNKWWNEVGTGICATKEDAPDAT-------PLDMNNLEGVFFVLLV 823
            ....:|||..:..|:|:....||...           .||.:       .:|:.:.....|.|.:
  Fly   561 EHLAHALLHFRATGLLQYNDKKWMVR-----------RPDCSLFKTSQAEVDLEHFAPALFALAL 614

  Fly   824 GSCCALLYGIISWVLFVMKKAHHYRVPLRDAL 855
            ..       :.|.::|:::...|:....|..|
  Fly   615 AM-------VASALVFLLELFLHWLPDFRRRL 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	42..396	CDD:107377	47/263 (18%)
		ANF_receptor	51..382	CDD:279440	45/249 (18%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	84/386 (22%)
		Lig_chan	551..824	CDD:278489	64/295 (22%)
Ir84a	NP_649720.2	nt_trans	<54..>112	CDD:294020	11/57 (19%)
		Periplasmic_Binding_Protein_Type_2	222..583	CDD:304360	92/446 (21%)
		Lig_chan	355..602	CDD:278489	61/282 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462827
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940