Protein Alignment GluRIIE and Nmdar2

DIOPT Version :9

• Sequence 1: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_001014714.1
• Gene: Nmdar2 / 31107
• FlyBaseID: FBgn0053513
• Length: 1083
• Species: Drosophila melanogaster
• Alignment Length: 966
• Identity: 200/966 - (20%)
• Similarity: 357/966 - (36%)
• Gaps: 271/966 - (28%)

  Fly    22 AQYENFGGYDNYQSLESVPIGL----------LTDQNTEQMNIVFDHAIDVANQEVGTSLTSLKE 76
            |.:.|||..:..:|:.:...||          |.|.:.||.||.||.          .|||....
  Fly   107 APHTNFGKREYLRSINNAVTGLTKTRGAKLTFLKDYSFEQKNIHFDM----------MSLTPSPT 161

  Fly    77 EVNYGDAYQSYGKLCR-MLETGIAGV--------FGPSSRHTAVHLMSICDAMDIPHIYSYMSEN 132
            .:        ...||: .|...::.:        ||.|:. :|.:.:.:...:.|| :.|:.::|
  Fly   162 AI--------LSTLCKEFLRVNVSAILYMMNNEQFGHSTA-SAQYFLQLAGYLGIP-VISWNADN 216

  Fly   133 AE----------GFNLHPHPADLAKALYSLITEFNWTRFIFLYESAEYLNILNELTTMLGKSGTV 187
            :.          ...|.|.....:.|:.|::..:.|.:|                        :|
  Fly   217 SGLERRASQSTLQLQLAPSIEHQSAAMLSILERYKWHQF------------------------SV 257

  Fly   188 ITVLRYDMQLNG--NYKQVLR-RVRK-------SVDNRIVVVGSSETMPEFLNQ----------- 231
            :|     .|:.|  ::.|.:| ||.:       ::.|.|||..:|:.| |.:|.
  Fly   258 VT-----SQIAGHDDFVQAVRERVAEMQEHFKFTILNSIVVTRTSDLM-ELVNSEARVMLLYATQ 316

  Fly   232 ---------AQQVGIINEDYKYIIG-----NLDFHS----------FDLEEYKYSEANITGLRLF 272
                     |:::.:..|:|.:::.     ..|.||          ||.............::::
  Fly   317 TEAITILRAAEEMKLTGENYVWVVSQSVIEKKDAHSQFPVGMLGVHFDTSSAALMNEISNAIKIY 381

  Fly   273 SPEKMAVKELLMKLGYPTDQDEFRNGSCPITVEMALTYDAVQLFAQTLKNLPFKPMPQNCSQRTE 337
            |   ..|:..|..   |.::|.                   :|..|:|          :|.....
  Fly   382 S---YGVEAYLTD---PANRDR-------------------RLTTQSL----------SCEDEGR 411

  Fly   338 SVRDDGSSFKNYMRTLRLTDRLLTGPIYF--EGNVRKGYHLDVIELQPSGIVKVGTWDEDRQYRP 400
            ...|:|..|..|:|.:.:...|....|.|  :|::|.. .|.::.|:||...|...|:|...::.
  Fly   412 GRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSA-ELKIMNLRPSANNKNLVWEEIGVWKS 475

  Fly   401 QRLAPTTAQFDSVDNSLANKTFIILLSVPNK-----------PYAQL------------------ 436
            ..    |.:.|..|.:....:......||.|           ||..|
  Fly   476 WE----TQKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLC 536

  Fly   437 -----------VETYKQLEGNSQYE---GYGVDLIKELADKLGFNFTFVN------GGNDYGSYN 481
                       ::..:.....|.|:   |:.:||:::.|::|||.:..|.      |..:.|.:|
  Fly   537 RVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGKWN 601

  Fly   482 KSTNESTGMLREIMTGRADLAITDLTITSEREQALDFTIPFMNLGIAILYLKPQKATPELFTFMD 546
                   |::.:::..:.|:.:|.|.|.:|||..:||:.|||..||||:..| :........|::
  Fly   602 -------GLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAK-RTGIISPTAFLE 658

  Fly   547 PFSEEVWWFLGF-SFLGVSLSFFILGRLSPSEWD----------NPYPCIEEPEELENQFTLGNS 600
            ||....|..:|. :....:...|:...||||.:|          .||           :|:|..:
  Fly   659 PFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTPY-----------RFSLFRT 712

  Fly   601 IWFTTGALLQQGSEI-GPKALSTRTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLA 664
            .|.....|.|....: .|:..::|.:.:.|..|.::.::.||||||||:...:.....:.::|..
  Fly   713 YWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSR 777

  Fly   665 -----DNKDGVVYGA---KKTGSTRNFFMTSAEERYKKMNKFMSENPQYLTEDNMEGVNRVKTNT 721
                 .:|....:|.   ..|.||       ..:.:..|:.:|.   ||......:||..|....
  Fly   778 LVHPFSHKPSFKFGTIPYSHTDST-------IHKYFNVMHNYMR---QYNKTSVADGVAAVLNGN 832

  Fly   722 HYAFLMESTSIEYNTKR--ECNLKKIGDALDEKGYGIAMRKDWPHRGKFNNALLELQEQGVLEKM 784
            ..:|:.:.|.::|...:  :|.|..:|......|||:|..::..:...||..|||.:..|.||::
  Fly   833 LDSFIYDGTVLDYLVAQDEDCRLMTVGSWYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERL 897

  Fly   785 KNKWWNEVGTGICAT-KEDAPDATPLDMNNLEGVFFVLLVGSCCALLYGIISWVLF 839
            :..|.    ||.|.. |::...:.||.:......|.:|:.|...|.|..::..|.|
  Fly   898 RRYWM----TGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYF 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	42..396	CDD:107377	80/429 (19%)
		ANF_receptor	51..382	CDD:279440	69/396 (17%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	99/441 (22%)
		Lig_chan	551..824	CDD:278489	67/295 (23%)
Nmdar2	NP_001014714.1	PBP1_iGluR_NMDA_NR2	99..490	CDD:107373	88/472 (19%)
		PBP2_iGluR_NMDA_Nr2	502..908	CDD:270436	100/438 (23%)
		Lig_chan	665..928	CDD:278489	65/287 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462857
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840