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Protein Alignment GluRIIE and Gria3

DIOPT Version :9

Sequence 1:	NP_001036733.1	Gene:	GluRIIE / 318623	FlyBaseID:	FBgn0051201	Length:	897	Species:	Drosophila melanogaster
Sequence 2:	NP_001106213.1	Gene:	Gria3 / 29628	RGDID:	70958	Length:	888	Species:	Rattus norvegicus

Alignment Length:	876	Identity:	292/876 - (33%)
Similarity:	458/876 - (52%)	Gaps:	91/876 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FVILWSLFSIHISVNWAQYENFGGYDNYQSLESVPIGLLTDQNTEQMNIVFDHAIDV--ANQEVG 68
            |::|..|...|           ||:.|     ::.||.|..:||.|.:..|..|:.:  .||...
  Rat    11 FLVLGLLGHSH-----------GGFPN-----TISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTT 59

  Fly    69 TSLTSLKEEVNYGDAYQSY---GKLCRMLETGIAGVFGPSSRHTAVHLMSICDAMDIPHIY-SYM 129
            .....|...|::.|:..|:   ...|.....|:..:||...:.:...|.|.|.|:....:. |:.
  Rat    60 EKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFP 124

  Fly   130 SENAEGFNLHPHPADLAKALYSLITEFNWTRFIFLYESAEYLNILNELTTMLGKSGTVITVLRYD 194
            ::....|.:...|| |..|:.||:..:.|.:|::||::....::|..:.....::...:|.
  Rat   125 TDADVQFVIQMRPA-LKGAILSLLGYYKWEKFVYLYDTERGFSVLQAIMEAAVQNNWQVTA---- 184

  Fly   195 MQLNGNYKQV--LRRVRKSVD----NRIVVVGSSETMPEFLNQAQQVGIINEDYKYIIGNLDFHS 253
             :..||.|.|  .||:.:.:|    .|.::....|.:...|.|...:|..:..|.|::.||.|..
  Rat   185 -RSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANLGFTD 248

  Fly   254 FDLEEYKYSEANITGLRLFSPEKMAVKELLMKLGYPTDQDEFRNG-SCPITVEMALTYDAVQLFA 317
            ..||...:..|||||.::.:.|...|::.:.: ....|:.||... :.|:....|||:||:.:.|
  Rat   249 ILLERVMHGGANITGFQIVNNENPMVQQFIQR-WVRLDEREFPEAKNAPLKYTSALTHDAILVIA 312

  Fly   318 QTLKNLPFKPMPQNCSQRTESVR--DDGSSFKN----------YMRTLRLTD-RLLTGPIYFEGN 369
            :..:.|.        .||.:..|  ..|....|          ..|.|::.. :.:||.|.|:..
  Rat   313 EAFRYLR--------RQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNIQFDTY 369

  Fly   370 VRK-GYHLDVIELQPSGIVKVGTWDEDRQYRPQRLAPTTAQFDSVDNSLANKTFIILLSVPNKPY 433
            .|: .|.:||.|::.||..|.|.|:|   |  :|..|.:.|..|.|:|.:....|::.::...||
  Rat   370 GRRTNYTIDVYEMKVSGSRKAGYWNE---Y--ERFVPFSDQQISNDSSSSENRTIVVTTILESPY 429

  Fly   434 AQLVETYKQLEGNSQYEGYGVDLIKELAD--KLGFNFTFVNGGNDYGSYNKSTNESTGMLREIMT 496
            ....:.::|||||.:||||.|||..|:|.  ::.:..:.|..|. ||:.:..|....||:.|::.
  Rat   430 VMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGK-YGARDPETKIWNGMVGELVY 493

  Fly   497 GRADLAITDLTITSEREQALDFTIPFMNLGIAILYLKPQKATPELFTFMDPFSEEVWWFLGFSFL 561
            ||||:|:..||||..||:.:||:.|||:|||:|:..||||:.|.:|:|:||.:.|:|..:.|:::
  Rat   494 GRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYI 558

  Fly   562 GVSLSFFILGRLSPSEW---DNPYPCIEEPEELE------NQFTLGNSIWFTTGALLQQGSEIGP 617
            |||:..|::.|.||.||   ||.    |||.:.:      |:|.:.||:||:.||.:|||.:|.|
  Rat   559 GVSVVLFLVSRFSPYEWHLEDNN----EEPRDPQSPPDPPNEFGIFNSLWFSLGAFMQQGCDISP 619

  Fly   618 KALSTRTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLADNKDGVVYGAKKTGSTRN 682
            ::||.|.|...|||||||::||||||||||||:|:..|.|.|.:|||...: :.||...:|||:.
  Rat   620 RSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTE-IAYGTLDSGSTKE 683

  Fly   683 FFMTSAEERYKKMNKFM-SENPQYLTEDNMEGVNRV-KTNTHYAFLMESTSIEYNTKRE-CNLKK 744
            ||..|....|:||..:| |..|...|:...:||.|| |:...:|||:|||..||..:|: |:..|
  Rat   684 FFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMK 748

  Fly   745 IGDALDEKGYGIAMRKDWPHRGKFNNALLELQEQGVLEKMKNKWW---NEVGTGICATKEDAPDA 806
            :|..||.||||:|..|........|.|:|:|.|||:|:|:|||||   .|.|:|    ..|:.|.
  Rat   749 VGGNLDSKGYGVATPKGSALGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSG----GGDSKDK 809

  Fly   807 T-PLDMNNLEGVFFVLLVGSCCALLYGIISW 836
            | .|.::|:.|||::|:.|...|::..:|.:
  Rat   810 TSALSLSNVAGVFYILVGGLGLAMMVALIEF 840

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.