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Protein Alignment GluRIIE and Gria2

DIOPT Version :9

Sequence 1:	NP_001036733.1	Gene:	GluRIIE / 318623	FlyBaseID:	FBgn0051201	Length:	897	Species:	Drosophila melanogaster
Sequence 2:	NP_001077280.1	Gene:	Gria2 / 29627	RGDID:	61862	Length:	883	Species:	Rattus norvegicus

Alignment Length:	929	Identity:	290/929 - (31%)
Similarity:	469/929 - (50%)	Gaps:	119/929 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ILWSLFSIHISVNWAQYENFGGYDNYQSLESVPIGLLTDQNTEQMNIVFDHAIDVANQEVGTS-- 70
            :||.|.             ||...|     |:.||.|..:..:|....|    .|...:..||
  Rat    14 VLWGLI-------------FGVSSN-----SIQIGGLFPRGADQEYSAF----RVGMVQFSTSEF 56

  Fly    71 -LTSLKEEVNYGDAYQSYGKLCRMLETGIAGVFGPSSRHTAVHLMSICDAMDIPHIY-SYMSENA 133
             ||...:.:...:::......|.....|:..:||...:.:...:.|.|..:.:..|. |:.::..
  Rat    57 RLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGT 121

  Fly   134 EGFNLHPHPADLAKALYSLITEFNWTRFIFLYESAEYLNILNELTTMLGKSGTVITVLRYDMQLN 198
            ..|.:...| ||..||.|||..:.|.:|.:||:|...|:.|..:.....:....:|.:... .:|
  Rat   122 HPFVIQMRP-DLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVG-NIN 184

  Fly   199 GN-----YKQVLRRVRKSVDNRIVVVGSSETMPEFLNQAQQVGIINEDYKYIIGNLDFHSFDLEE 258
            .:     |:.:.:.:....:.|:::....:.:.:.::|...:|...:.|.|||.||.|...||.:
  Rat   185 NDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLK 249

  Fly   259 YKYSEANITGLRLFSPEKMAVKELLMKLGYPTDQDEFRNGSCPITVE--MALTYDAVQLFAQTLK 321
            .::..||::|.::...:...|.:.:.:  :.|.:::...|:...|::  .||||||||:..:..:
  Rat   250 IQFGGANVSGFQIVDYDDSLVSKFIER--WSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFR 312

  Fly   322 NLPFKPMPQNCSQRTESVR---------------DDGSSFKNYMRTLRLTDRLLTGPIYFEGNVR 371
            ||.        .||.|..|               ..|...:..::.:::..  |:|.|.|:.|.:
  Rat   313 NLR--------KQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEG--LSGNIKFDQNGK 367

  Fly   372 K-GYHLDVIELQPSGIVKVGTWDEDRQYRPQRLAPTTAQFDSVDNS--LANKTFIILLSVPNKPY 433
            : .|.::::||:.:|..|:|.|.|     ..::..|..:..|.:::  |.||| :::.::...||
  Rat   368 RINYTINIMELKTNGPRKIGYWSE-----VDKMVVTLTELPSGNDTSGLENKT-VVVTTILESPY 426

  Fly   434 AQLVETYKQLEGNSQYEGYGVDLIKELADKLGFNF--TFVNGGNDYGSYNKSTNESTGMLREIMT 496
            ..:.:.::.||||.:||||.|||..|:|...||.:  |.|..|. ||:.:..|....||:.|::.
  Rat   427 VMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGK-YGARDADTKIWNGMVGELVY 490

  Fly   497 GRADLAITDLTITSEREQALDFTIPFMNLGIAILYLKPQKATPELFTFMDPFSEEVWWFLGFSFL 561
            |:||:||..||||..||:.:||:.|||:|||:|:..||||:.|.:|:|:||.:.|:|..:.|:::
  Rat   491 GKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYI 555

  Fly   562 GVSLSFFILGRLSPSEWDNPYPCIEEPE--------ELENQFTLGNSIWFTTGALLQQGSEIGPK 618
            |||:..|::.|.||.||..     ||.|        |..|:|.:.||:||:.||.::||.:|.|:
  Rat   556 GVSVVLFLVSRFSPYEWHT-----EEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPR 615

  Fly   619 ALSTRTVASFWWFFTLIVVSSYTANLAAFLTIEKPQSLINSVDDLADNKDGVVYGAKKTGSTRNF 683
            :||.|.|...|||||||::||||||||||||:|:..|.|.|.:||:...: :.||...:|||:.|
  Rat   616 SLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTE-IAYGTLDSGSTKEF 679

  Fly   684 FMTSAEERYKKMNKFM-SENPQYLTEDNMEGVNRV-KTNTHYAFLMESTSIEYNTKRE-CNLKKI 745
            |..|....:.||..:| |..|........|||.|| |:...||:|:|||..||..:|: |:..|:
  Rat   680 FRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKV 744

  Fly   746 GDALDEKGYGIAMRKDWPHRGKFNNALLELQEQGVLEKMKNKWW---NEVGTGICATKEDAPDAT 807
            |..||.||||||..|........|.|:|:|.|||:|:|:|||||   .|.|:|...:||   ..:
  Rat   745 GGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKE---KTS 806

  Fly   808 PLDMNNLEGVFFVLLVGSCCALLYGIISWVLFVMKKAHHYRVPLRDALKEEFQFVIDFNNYVRVL 872
            .|.::|:.|||::|:.|...|:|..:|.   |..|.        |...|.           ::|.
  Rat   807 ALSLSNVAGVFYILVGGLGLAMLVALIE---FCYKS--------RAEAKR-----------MKVA 849

  Fly   873 KNSASIYSRSRQSSMSVAS 891
            ||..:|...|.|:|.:.|:
  Rat   850 KNPQNINPSSSQNSQNFAT 868

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.