Protein Alignment GluRIIE and grid2

DIOPT Version :9

• Sequence 1: NP_001036733.1
• Gene: GluRIIE / 318623
• FlyBaseID: FBgn0051201
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: XP_031759030.1
• Gene: grid2 / 100487676
• XenbaseID: XB-GENE-955038
• Length: 1007
• Species: Xenopus tropicalis
• Alignment Length: 981
• Identity: 248/981 - (25%)
• Similarity: 435/981 - (44%)
• Gaps: 178/981 - (18%)

  Fly     5 HFVILWSLFSIHISVNWAQYENFGGYDNYQSLESVPIGLLTDQNTEQMNIVFDHAI-------DV 62
            |..|..|:|   .:|:|       |.....|:  :.||.:.|::.::.:.||..|:       |:
 Frog     5 HAFICMSVF---WTVSW-------GRTRADSI--IHIGAIFDESAKKDDEVFRMAVADLNLNEDI 57

  Fly    63 ANQEVGTSLTSLKEEVNYGDAYQSYGKLCRMLETGIAGVFGPSSRHTAVHLMSICDAMDIPHIYS 127
            ...|   .:|.....|:..:.:|:..:.|.::..||..:.......:|..|.|:.|||.|||::.
 Frog    58 LQTE---KITFSVTFVDGNNPFQAVQEACDLMSQGILALVSSIGCASAGSLQSLADAMHIPHLFI 119

  Fly   128 YMS-----------ENAEG-----FNLHPHPADLAKALYSLITEFNWTRFIFLYESAEYLNILNE 176
            ..|           :.:.|     .::.| |..|...:..::||:.|.:||..|::...:..:.|
 Frog   120 QRSTARTPRSGCGLQRSSGIDDYTLSVRP-PVYLNDVILRVVTEYAWQKFIVFYDNNYDIRGIQE 183

  Fly   177 LTTMLGKSGTVITVLRYDMQLN---------------GNYKQVLRRVRKSVDNRIVVVGSSETMP 226
            ....:.:.|..:.:.:.:..:|               ..|:..|||.        ::|.|..|..
 Frog   184 FLDRVSQQGMDVALQKVENNINRMITGLFATMRIEELNRYRDTLRRA--------ILVMSPTTAK 240

  Fly   227 EFLNQAQQVGIINEDYKYIIGNLDFHSFDLEE-YKYSEANITGLRLFSPEKMAVKELLMKLGYPT 290
            .|:.:..:..::..|..:||.|.:.:..|::| .:.|...:|.:|...|           :.:.:
 Frog   241 AFITEVVETNLVAFDCHWIIINEEINDLDVQELVRRSIGRLTIIRQTFP-----------VPHNS 294

  Fly   291 DQDEFRNGS------C----PITVEMALT----YDAVQL----FAQTLKNLPFKPMPQ-NCSQRT 336
            .|..||...      |    |.:..|.:|    ||.|.|    |.:.|::..:..|.. .|.::.
 Frog   295 SQRCFRGNHRISTSLCDPKDPFSQNMEITNMYIYDTVLLLANAFHKKLEDRKWHSMASLTCIRKN 359

  Fly   337 ESVRDDGSSFKNYMRTLRLTDRLLTGPIYF-EGNVRKGYHLDVI-----ELQPSGIVKVGTWDED 395
            ......|.|....::...::.  |||.:.| |.......:.:::     |....||.|:|.|:
 Frog   360 SKPWQGGRSMLETVKKGGVSG--LTGALDFSEDGGNPNIYFEILGTNYGEELGRGIRKLGFWN-- 420

  Fly   396 RQYRPQRLAPTTAQFDSV-DNSLANKTFIILL---SVPNKPYAQLVETYKQLEGNSQYEGYGVDL 456
                     |.|....|: |..|.|....::|   :|..:|:..:.|..  |....:|:|:.:|:
 Frog   421 ---------PVTGLNGSLTDRKLENNMRGVVLRVATVLEEPFVMVSENV--LGKPKKYQGFSIDV 474

  Fly   457 IKELADKLGFNF-TFVNGGNDYGSYNKSTNESTGMLREIMTGRADLAITDLTITSEREQALDFTI 520
            :..|:..|||.: .:|...:.||| .::.....|::.|::..|||:.|:.||||.:||..:|||.
 Frog   475 LDALSSYLGFKYEIYVASDHKYGS-PQADGSWNGLIGELLLKRADMGISALTITPDRENVVDFTT 538

  Fly   521 PFMNLGIAILYLKPQKATPELFTFMDPFSEEVWWFLGFSFLGVSLSFFILGRLSPSEWDNPYPCI 585
            .:|:..:.:|..|.:| |.::|..:.||...:|..:..:.|.|.|..::|      .|.|| |.:
 Frog   539 RYMDYSVGVLLRKAEK-TVDMFACLAPFDLSLWACIAGTVLLVGLLVYLL------NWLNP-PRL 595

  Fly   586 EEPEELENQFTLGNSIWFTTGALLQQGSEIGPKALSTRTVASFWWFFTLIVVSSYTANLAAFLTI 650
            :.......  ||.||:||..|:.:|||.|:....|:||.:...||.|.|||:|||||||||||||
 Frog   596 QMGSMTST--TLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTI 658

  Fly   651 EKPQSLINSVDDLADNKDGVVYGAKKTGSTRNFFMTSAEE--RYKKMNKF--------------M 699
            .:.:|.|.|:.||:...| :.||        ..|.::..|  |.|.||.|              .
 Frog   659 SRIESSIQSLQDLSRQTD-IPYG--------TVFDSAVYEHVRVKGMNPFERDSMYSQMWRMINR 714

  Fly   700 SENPQYLTEDNMEGVNRVKTNTHYAFLMESTSIEY--NTKRECNLKKIGDALDEKGYGIAMRKDW 762
            |...:...::::||:.:|| :.:|||:.::..:||  ...::|:...:|:.:.::|||||::...
 Frog   715 SNGSENNVQESLEGIQKVK-HGNYAFVWDAAVLEYIAINDQDCSFYTVGNTIADRGYGIALQHGS 778

  Fly   763 PHRGKFNNALLELQEQGVLEKMKNKWWNEVGTGIC---ATKEDAPDATPLDMNNLEGVFFVLLVG 824
            |:|..|:..:||||:.|.::.:|:|||..  .|.|   ::.:.....:.||:.:..|||.:|..|
 Frog   779 PYRDIFSQRILELQQNGDMDILKHKWWPR--NGQCELHSSMDTKQKGSSLDIKSFSGVFCILAAG 841

  Fly   825 ---SCCALLYGIISWVLFVMKKAHHYRVPLRDALKEEFQFVIDFNNYVRVLKNSASIYSRSRQSS 886
               ||...:  :.:|    ..|....|||.::..||     ||..:..|.: ||......|....
 Frog   842 IVLSCFIAM--VETW----WNKKKGSRVPSKEDDKE-----IDLEHLHRRV-NSLCTDDESPHKQ 894

  Fly   887 MSVASV 892
            .|.:|:
 Frog   895 FSTSSI 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRIIE	NP_001036733.1	PBP1_iGluR_Kainate	42..396	CDD:107377	82/417 (20%)
		ANF_receptor	51..382	CDD:279440	75/394 (19%)
		PBP2_iGluR_Kainate	419..790	CDD:270432	125/392 (32%)
		Lig_chan	551..824	CDD:278489	94/293 (32%)
grid2	XP_031759030.1	Periplasmic_Binding_Protein_type1	28..429	CDD:415822	85/436 (19%)
		PBP2_iGluR_delta_2	440..806	CDD:270449	124/388 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910