Protein Alignment CG31198 and AAP1

DIOPT Version :10

• Sequence 1: NP_732654.1
• Gene: CG31198 / 318622
• FlyBaseID: FBgn0051198
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_011913.1
• Gene: AAP1 / 856443
• SGDID: S000001089
• Length: 856
• Species: Saccharomyces cerevisiae
• Alignment Length: 908
• Identity: 243/908 - (26%)
• Similarity: 443/908 - (48%)
• Gaps: 97/908 - (10%)

  Fly    43 LAEHITPVNYNITLRPYLLETDGNKRFTFDGEVWIEVISNQTTNDIYLHSKNLTYSVREYWQKPT 107
            |..::||::|:|||.|..      :.|||:|.:.|::    ..||..::|..:.|...::   .:
Yeast     6 LPNNVTPLHYDITLEPNF------RAFTFEGSLKIDL----QINDHSINSVQINYLEIDF---HS 57

  Fly   108 TEVANPTVIQISATNTTNYDTDIVKLTASTALTANTTY-------ILHFVYTGLMEDDMHGFYRS 165
            ..:.....|:::......         .:|.:..|.|:       .|..:::|::.|.|.||||:
Yeast    58 ARIEGVNAIEVNKNENQQ---------KATLVFPNGTFENLGPSAKLEIIFSGILNDQMAGFYRA 113

  Fly   166 SYVDD-NNVTKWLGSTQFQTHHARRAFPSFDEPQFKATFDVTLKRHRTFNSVSNTRLISSYPSTE 229
            .|.|. ...||::.:||.:...||||||.||||..||||.|||........:||..:.:.  :.:
Yeast   114 KYTDKVTGETKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNE--TIK 176

  Fly   230 EGIFSDVYKTTPKMSTYLLAFIISEFVARKDDDF----GVYARPEYYAQTQYPYNVGIQILEEMG 290
            ||.....:.|||||||||:|||:::....:.::|    .||:.|......|:..|:..:.|....
Yeast   177 EGKKYTTFNTTPKMSTYLVAFIVADLRYVESNNFRIPVRVYSTPGDEKFGQFAANLAARTLRFFE 241

  Fly   291 QYLDKDYYSMGNDKMDMAAIPDFSAGAMENWGLLTYRERSLLVDESATTLASRQSIAAVVAHEQA 355
            ...:.:|   ...||||.|:.:|||||||||||:|||...||:|...::|...|.:|.|:.||.|
Yeast   242 DTFNIEY---PLPKMDMVAVHEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVIQHELA 303

  Fly   356 HMWFGDLVTCKWWSYTWLNEGFARYFQYFGTAMVEDKWELEKQFVVDQVQSVMAMDSTNATNPL- 419
            |.|||:|||..||...|||||||.:..::.....:.:|::.:|:|.|.:|..:.:||..:::|:
Yeast   304 HQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNLDSLRSSHPIE 368

  Fly   420 -----SDENTYTPAHLSRMFNSISYNKGATFIRMIKHTMGEQQFQKSLQEYLKKYEYQSSLPEYL 479
                 :||       ::::|::|||:||::.:|||...:||:.|.|.:.:||.|::|.::....|
Yeast   369 VPVNNADE-------INQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTGDL 426

  Fly   480 LGAWQANWPNSSYNESSKD---IFKSFTEQVGYPLINVTVGNSQVSFTQKRFL----LKESDGSD 537
               |.|     ..:.|.||   :...:|::||:|:::|....::::.||.|:|    :||.:  |
Yeast   427 ---WDA-----LADASGKDVCSVMNIWTKRVGFPVLSVKEHKNKITLTQHRYLSTGDVKEEE--D 481

  Fly   538 SSLKYTVPISYTTSETNNFLNTTPKFILKPNVTTTVQFNSTIKWIVVNIQQTGYYRVTYSDDNWH 602
            :::   .||.....::....||   .:|.....|....|.  ::..:|..|:|.:..:|||:.|
Yeast   482 TTI---YPILLALKDSTGIDNT---LVLNEKSATFELKNE--EFFKINGDQSGIFITSYSDERW- 537

  Fly   603 AIHHALITANWGGIHENNRAQIVDDLFNLARAGYVTYNLTLDVIEYLQTETNYIPWTSAFNGFNY 667
                |.::.....:...:|..:|.|...|:.:||.:....|::|...:.|.:::.|....|..:.
Yeast   538 ----AKLSKQANLLSVEDRVGLVADAKALSASGYTSTTNFLNLISNWKNEDSFVVWEQIINSLSA 598

  Fly   668 LTIRLGNDTADF-----NYYIQTLTNKAYNQLGFNEASNDTALDIYLRTKILSWACRYGSSDCIS 727
            |......:..|.     .:.:..:.|| .::||:|...:|:.....|:..:.|.||..|:....|
Yeast   599 LKSTWVFEPEDILNALDKFTLDLVLNK-LSELGWNIGEDDSFAIQRLKVTLFSAACTSGNEKMQS 662

  Fly   728 QAQGYFQSLA-----TVPKNIRATVYCVGLREGGEAEFQALYNKFKNETVATEETLLQNSFGCVK 787
            .|...|:..|     .:|...:|.|:....|.|||..::.::|.::|...:.|:.:...:.|..:
Yeast   663 IAVEMFEEYANGNKQAIPALFKAVVFNTVARLGGENNYEKIFNIYQNPVSSEEKIIALRALGRFE 727

  Fly   788 TQSLIEKVFDLIISDEIRRQDKSSVLATLYTENNENVSPVFALVTQKYEELAEAM-GGYSAVATV 851
            .:.|:|:....::...:..||....:..:.. :.:.:..::|.:.:.::|:|:.: .|...:..|
Yeast   728 DKELLERTLSYLLDGTVLNQDFYIPMQGIRV-HKKGIERLWAWMQEHWDEIAKRLQPGSPVLGGV 791

  Fly   852 ISNIAARFTTNQQLTDLENFNKANGAKFGSSQATLTAAEATVKENLEWATAKLGVFRSYLANY 914
            ::.....||:.:.|..:..|......| |..| ||..|..|::...:|.:....:..:||..:
Yeast   792 LTLGLTNFTSFEALEKISAFYSRKVTK-GFDQ-TLAQALDTIRSKAQWVSRDREIVATYLREH 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31198	NP_732654.1	M1_APN-Q_like	50..505	CDD:341064	151/475 (32%)
		ERAP1_C	581..898	CDD:463368	67/327 (20%)
AAP1	NP_011913.1	M1_APN-Q_like	13..447	CDD:341064	151/475 (32%)
		ERAP1_C	517..833	CDD:463368	67/324 (21%)