DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31198 and APM1

DIOPT Version :9

Sequence 1:	NP_732654.1	Gene:	CG31198 / 318622	FlyBaseID:	FBgn0051198	Length:	940	Species:	Drosophila melanogaster
Sequence 2:	NP_195035.2	Gene:	APM1 / 829446	AraportID:	AT4G33090	Length:	879	Species:	Arabidopsis thaliana

Alignment Length:	904	Identity:	252/904 - (27%)
Similarity:	446/904 - (49%)	Gaps:	95/904 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 EYRLAEHITPVNYNITLRPYLLETDGNKRFTFDGEVWIEVISNQTTNDIYLHSKNLTYSVRE--- 101
            |.||.:...|..|::.|.|.|:..      ||.|.|.|::.....|..|.|::.:|  ||.:
plant     7 EPRLPKFAVPKRYDLRLNPDLIAC------TFTGTVAIDLDIVADTRFIVLNAADL--SVNDASV 63

  Fly   102 YWQKPTTEVANPTVIQISATNTTNYDTDIVKLTASTALTANTTYILHFVYTGLMEDDMHGFYRSS 166
            .:..|::..|      ::|.....::.|.:.:.....:..:...:|...:.|::.|.|.|||||:
plant    64 SFTPPSSSKA------LAAPKVVLFEEDEILVLEFGEILPHGVGVLKLGFNGVLNDKMKGFYRST 122

  Fly   167 YVDDNNVTKWLGSTQFQTHHARRAFPSFDEPQFKATFDVTLKRHRTFNSVSNTRLISSYPSTEEG 231
            | :.|...|.:..|||:...|||.||.:|||..||||.:||:......::||      .|..||.
plant   123 Y-EHNGEKKNMAVTQFEPADARRCFPCWDEPACKATFKITLEVPTDLVALSN------MPIMEEK 180

  Fly   232 IFSDV----YKTTPKMSTYLLAFIIS--EFVARKDDD---FGVYARPEYYAQTQYPYNVGIQILE 287
            :..::    |:.:|.|||||:|.::.  ::|.....|   ..||.:.....|.::..:||.:.|:
plant   181 VNGNLKIVSYQESPIMSTYLVAIVVGLFDYVEDHTSDGIKVRVYCQVGKADQGKFALHVGAKTLD 245

  Fly   288 EMGQYLDKDYYSMGN--DKMDMAAIPDFSAGAMENWGLLTYRERSLLVDESATTLASRQSIAAVV 350
                 |.|:|:::..  .||||.|||||:||||||:||:||||.:||.||..:..:::|.:|.||
plant   246 -----LFKEYFAVPYPLPKMDMIAIPDFAAGAMENYGLVTYRETALLYDEQHSAASNKQRVATVV 305

  Fly   351 AHEQAHMWFGDLVTCKWWSYTWLNEGFARYFQYFGTAMVEDKWELEKQFVVDQVQSVMAMDSTNA 415
            |||.||.|||:|||.:||::.|||||||.:..|..|..:..:|::..|| :|:....:.:|....
plant   306 AHELAHQWFGNLVTMEWWTHLWLNEGFATWVSYLATDSLFPEWKIWTQF-LDESTEGLRLDGLEE 369

  Fly   416 TNPLSDENTYTPAHLSRMFNSISYNKGATFIRMIKHTMGEQQFQKSLQEYLKKYEYQSSLPEYLL 480
            ::|:..|..:. |.:..:|::|||.|||:.|||::..:|.:.|||||..|:|.:.|.::..|.|.
plant   370 SHPIEVEVNHA-AEIDEIFDAISYRKGASVIRMLQSYLGAEVFQKSLAAYIKNHAYSNAKTEDLW 433

  Fly   481 GAWQANWPNSSYNESSKDIFKSFTEQVGYPLINVTVGNSQVSFTQKRFLLKESDGSDSSLKYTVP 545
            .|.:|     ...|....:..|:|:|.|||:::..:.:.::...|.|||   |.||....::.||
plant   434 AALEA-----GSGEPVNKLMSSWTKQKGYPVVSAKIKDGKLELEQSRFL---SSGSPGEGQWIVP 490

  Fly   546 I-----SYTTSETNNFL--NTTPKFILKPNVTTTV-----QFNSTIKWIVVNIQQTGYYRVTYSD 598
            :     ||  .:..|||  :.:..:.||..:..::     :.|.|..||.:|:.|.|:|||.|.|
plant   491 VTLCCGSY--EKRKNFLLESKSGAYDLKELLGCSIADGSDKINGTCSWIKINVDQAGFYRVKYDD 553

  Fly   599 DNWHAIHHALITANWGGIHENNRAQIVDDLFNLARAGYVTYNLTLDVIEYLQTETNYIPWTSAFN 663
            .....:.:|..:.:...|   :|..|:||.|.|..|...:....|.:....:.|.:|...::..
plant   554 SLAAGLRNATESQSLTSI---DRYGILDDSFALTMARQQSLASLLTLCSAYKKELDYTVLSNLI- 614

  Fly   664 GFNYLTIRLGNDT-----ADFNYYIQTLTNKAYNQLGFNEASNDTALDIYLRTKILSWACRYGSS 723
            ..:|..:::|.|.     :...::...:...|..:||::....::.||..||.::|:....:|..
plant   615 AISYKVVKIGADANQELMSGIKHFFIGVFQFAAGKLGWDPKQGESHLDAMLRGEVLTALAVFGHD 679

  Fly   724 DCISQAQGYFQSLAT------VPKNIRATVYCVGLREGGEAE---FQALYNKFKNETVATEETLL 779
            :.:.:|...|.:...      :|.:||...|...::...:::   :::|...::...::.|:|.:
plant   680 ETLKEAVRRFDAFLADRNTPLLPPDIRRAAYVAVMQRANKSDKSGYESLLRVYRETDLSQEKTRI 744

  Fly   780 QNSFGCVKTQSLIEKVFDLIISDEIRRQDKSSVLATLYTENNENVSPVFALVTQKYEELAEAMGG 844
            ..|.......::::.|.:.::|||:|.||....|:.:..|..|   ..:..:.:|:|.:....|.
plant   745 LGSLASCPDPTIVQDVLNFVLSDEVRNQDALYGLSGVSWEGRE---VAWKWLQEKWEYIGNTWGS 806

  Fly   845 YSAVATVISNIAARFTTNQQLTDLENF----NKANGAKFGSSQATLTAAEATVKENLEW 899
            ...:...||.:.:.|.:.::..::|.|    :|.:.|:      ||..:...|..|..|
plant   807 GFLITRFISAVVSPFASFEKAKEVEEFFATRSKPSMAR------TLKQSIERVHINANW 859

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31198	NP_732654.1	Peptidase_M1	42..442	CDD:279741	138/413 (33%)
		M1_APN_2	50..510	CDD:189008	159/473 (34%)
		ERAP1_C	582..898	CDD:288671	67/333 (20%)
APM1	NP_195035.2	M1_APN-Q_like	18..453	CDD:341064	156/467 (33%)
APM1	NP_195035.2	ERAP1_C	536..855	CDD:403137	67/331 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X67
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920