Protein Alignment CG31198 and npepps

DIOPT Version :10

• Sequence 1: NP_732654.1
• Gene: CG31198 / 318622
• FlyBaseID: FBgn0051198
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_001157499.1
• Gene: npepps / 407726
• ZFINID: ZDB-GENE-060524-3
• Length: 872
• Species: Danio rerio
• Alignment Length: 913
• Identity: 265/913 - (29%)
• Similarity: 441/913 - (48%)
• Gaps: 100/913 - (10%)

  Fly    42 RLAEHITPVNYNITLRPYLLETDGNKRFTFDGEVWIEVISNQTTNDIYLHSKNLTYSVREYWQKP 106
            ||...:.||||.:.|:|.|::      |||:|::...|...|.||.|.::..::
Zfish     9 RLPTDVYPVNYGLRLKPDLVD------FTFEGKLEAAVEVTQGTNQIVMNCADI----------- 56

  Fly   107 TTEVANPTVI-----QISAT--NTTNYDTDIVKLTASTALTANTTYILHFVYTGLMEDDMHGFYR 164
              ::...:.:     :|:||  |..|.|..:.....||....:.:..:.||  |.:.|.|.||||
Zfish    57 --DIITASFVPDGGEEINATGFNYQNEDEKVTLCFPSTLQKGSGSLKIDFV--GELNDKMKGFYR 117

  Fly   165 SSYVDDNNVTKWLGSTQFQTHHARRAFPSFDEPQFKATFDVTLKRHRTFNSVSNTRLISSYPSTE 229
            |.|.....| ::...|||:...||||||.:|||..|||||:||...:...::||..::...|..|
Zfish   118 SKYSSSGEV-RYAAVTQFEATDARRAFPCWDEPAIKATFDITLIVPKDRVALSNMNVVDRKPYAE 181

  Fly   230 EGIFSDV-YKTTPKMSTYLLAFIISE--FVARKDDD---FGVYARPEYYAQTQYPYNVGIQILEE 288
            :....:| :.|||.|||||:||:|.|  ||..:..|   ..||.......|.::...|..:.|.
Zfish   182 DQSLVEVKFATTPIMSTYLVAFVIGEYDFVESQSSDGVTVRVYTPVGKAEQGKFALEVATKTLP- 245

  Fly   289 MGQYLDKDYYSMGN--DKMDMAAIPDFSAGAMENWGLLTYRERSLLVDESATTLASRQSIAAVVA 351
                ..|||:|:..  .|:|:.||.||:|||||||||:||||.:||:|...:..:|||.:|.||.
Zfish   246 ----FYKDYFSVPYPLPKIDLIAIADFAAGAMENWGLVTYRETALLIDPKNSCASSRQWVALVVG 306

  Fly   352 HEQAHMWFGDLVTCKWWSYTWLNEGFARYFQYFGTAMVEDKWELEKQFVVDQVQSVMAMDSTNAT 416
            ||.||.|||:|||.:||::.|||||||.:.:|........::::..|||.......:.:|:.:.:
Zfish   307 HELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRALDLDALDNS 371

  Fly   417 NPLSDENTYTPAHLSRMFNSISYNKGATFIRMIKHTMGEQQFQKSLQEYLKKYEYQSSLPEYLLG 481
            :|: :.:...|:.:..:|::|||:|||:.|||:.:.:|::.|:|.:..||.|::::::..|.|
Zfish   372 HPI-EVDVGHPSEVDEIFDAISYSKGASVIRMLHNYIGDEDFRKGMNAYLLKFQHKNASTEDL-- 433

  Fly   482 AWQANWPNSSYNESSKDI---FKSFTEQVGYPLINVTV---GNSQV-SFTQKRFLLKESDGSDSS 539
             |:.     ....|.|.|   ..|:|:|:|:|:|.|..   |:.:| ..:||:|........:..
Zfish   434 -WEC-----LEQASGKPIAAVMNSWTKQMGFPIIVVDQEQHGSDRVLKISQKKFCASGPRNDEDC 492

  Fly   540 LKYTVPISYTTSETNNFLNTTPKFIL-KPNVTTTVQFNSTIKWIVVNIQQTGYYRVTYSDDNWHA 603
            ..:.||||..|||..:...|  |.:| :|..|..:...:...||.:|....|:||:.||.
Zfish   493 PNWMVPISICTSEDPSCTKT--KILLDQPETTVNITNVAPDHWIKINPGTVGFYRIQYSS----- 550

  Fly   604 IHHALITANWGGIHE-----NNRAQIVDDLFNLARAGYVTYNLTLDVIEYLQTETNYIPWTSAFN 663
               |::.:...||.:     .:|..:.:|||:|||||.::....|.|:|....|.||..|:....
Zfish   551 ---AMLESLLPGIRDLTLLPVDRLGLQNDLFSLARAGMISTVEVLKVMEAFVNEPNYTVWSDLSC 612

  Fly   664 GFNYLTIRLGNDTADFNYYIQTLTNKAYN----QLGFNEASNDTALDIYLRTKILSWACRYGSSD 724
            ....|:..|.:  .||:..||......:.    :||::..:.:..||..||..:|....:.|...
Zfish   613 NLGVLSSLLSH--TDFHEDIQEFIRDLFTPIGMKLGWDSRTGEGHLDALLRGLVLGKLGKAGHKA 675

  Fly   725 CISQAQGYF----QSLATVPKNIRATVYCVGLREGGEAEFQALYNKFKNETVATEETLLQNSFGC 785
            .:.:|:..|    :....:..::|:.||...|:.|.......:....|...:..|:..::...|.
Zfish   676 TLEEARRRFREHVEGKQILSADLRSPVYLTVLKHGDSTTLDTMLKLHKQADMQEEKNRIERVLGA 740

  Fly   786 VKTQSLIEKVFDLIISDEIRRQDKSSVLATLYTENNENVSPVFALVTQKYEELAEAMGGYSAVAT 850
            :....||::|.:..:|:|:|.||..||:..:...:.:.....:..|...:|||.....|...::.
Zfish   741 IPAPDLIQRVLNFALSEEVRPQDTVSVIGGVAGSSKQGRKAAWKFVKDNWEELHNRYQGGFLISR 805

  Fly   851 VISNIAARFTTNQQLTDLENFNKANGAKFGSSQATLTAAEATVKE-------NLEWATAKLGVFR 908
            :|......|..::...::::|.:::.|         .|||.||::       |..|.........
Zfish   806 LIKLTVDGFAIDKMAAEVKSFFESHHA---------PAAERTVQQCCENILLNAAWLKRDADDIH 861

  Fly   909 SYL 911
            .||
Zfish   862 QYL 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31198	NP_732654.1	M1_APN-Q_like	50..505	CDD:341064	160/472 (34%)
		ERAP1_C	581..898	CDD:463368	76/336 (23%)
npepps	NP_001157499.1	M1_APN-Q_like	17..454	CDD:341064	160/472 (34%)
		ERAP1_C	533..846	CDD:463368	75/331 (23%)