Protein Alignment CG31198 and Rnpep

DIOPT Version :9

• Sequence 1: NP_732654.1
• Gene: CG31198 / 318622
• FlyBaseID: FBgn0051198
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_663392.2
• Gene: Rnpep / 215615
• MGIID: 2384902
• Length: 650
• Species: Mus musculus
• Alignment Length: 544
• Identity: 126/544 - (23%)
• Similarity: 208/544 - (38%)
• Gaps: 142/544 - (26%)

  Fly   180 TQFQTHHARRAFPSFDEPQFKATFDVTLKRHRTFNSVSNTRLISSYPSTEEGIFSDVYKTTPKMS 244
            ||.|....|..||.||.|..|.|:...::....|     |.::|:....:.|.....::.:..:.
Mouse   168 TQGQAVLNRAFFPCFDTPAVKCTYSALIEVPDGF-----TAVMSADTWEKRGPNKFFFQMSHPIP 227

  Fly   245 TYLLAFIISEFVARKDDDFG----VYARPEYYAQTQYPYNVGIQILEEMGQYLDKDYYSMGNDKM 305
            :||:|..|.:..:.   :.|    |:|.|......:..|:..|:.....|:.|...|.....|.:
Mouse   228 SYLIALAIGDLASA---EVGPRSRVWAEPCLIEAAKEEYSGVIEEFLATGEKLFGPYVWGRYDLL 289

  Fly   306 DMAAIPDFSAGAMENWGLLTYRERSLLVDESATTLASRQSIAAVVAHEQAHMWFGDLVTCKWWSY 370
            .|.  |.|..|.||| ..||:....|        ||..:|:|.|:.||.:|.|||:|||...|..
Mouse   290 FMP--PSFPFGGMEN-PCLTFVTPCL--------LAGDRSLADVIIHEISHSWFGNLVTNANWGE 343

  Fly   371 TWLNEGFARYFQ------YFGTAMVEDKWELEKQFVVDQVQSVMA-----MDSTNATNPLS---- 420
            .||||||..|.|      .||.|           :...:..:..|     |:.:...|||:
Mouse   344 FWLNEGFTMYAQRRISTILFGAA-----------YTCLEAATGRALLRQHMNVSGEENPLNKLRV 397

  Fly   421 -------DENTYTPAHLSRMFNSISYNKGATFIRMIKHTMGEQ-QFQKSLQEYLKKYEYQSSLPE 477
                   .::||         |...|.||..|:..:.|.:|:| ||.|.|:.|:.::::||.|.|
Mouse   398 KIEPGVDPDDTY---------NETPYEKGYCFVSYLAHLVGDQDQFDKFLKAYVDEFKFQSILAE 453

  Fly   478 YLLGAWQANWPNSSYNESSKDI-------FKSFTEQVGYP--LINVTVGNSQVSFTQKRFLLKES 533
            ..|..:...:|..    ..|.:       |..:....|:|  |.:::.|:|         |:|.:
Mouse   454 DFLEFYLEYFPEL----KKKGVDSIPGFEFDRWLNTPGWPPYLPDLSPGDS---------LMKPA 505

  Fly   534 D-------GSDSSLKYTVPISYTTSETNNFLNTTPKFILK---------------PNVTTTVQFN 576
            :       .|:..::....::.:|.:|...:....|.:.|               |.::......
Mouse   506 EELAELWVTSEPDMQAIEAVAISTWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAE 570

  Fly   577 STIKW---IVVN------------IQQTGYYRVTYSDDNWHAIHHALITANWGGIHENNRAQIVD 626
            ..::|   |:.|            :|..|..:.|.      .::||::    || .|..|. :..
Mouse   571 LRLRWGQIILKNDYQEEFQKVKDFLQSQGKQKYTL------PLYHAMM----GG-SEMART-LAK 623

  Fly   627 DLFNLARAGYVTYNLTLDVIEYLQ 650
            |.| .|.|..:..|    |:.|:|
Mouse   624 DTF-AATASQLHSN----VVNYVQ 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31198	NP_732654.1	Peptidase_M1	42..442	CDD:279741	74/287 (26%)
		M1_APN_2	50..510	CDD:189008	94/363 (26%)
		ERAP1_C	582..898	CDD:288671	19/81 (23%)
Rnpep	NP_663392.2	leuko_A4_hydro	24..634	CDD:274120	122/530 (23%)
		M1_LTA4H	24..484	CDD:189006	93/358 (26%)
		Substrate binding. /evidence=ECO:0000250	298..302		2/3 (67%)
		Leuk-A4-hydro_C	504..644	CDD:286244	26/156 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1831
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760