Protein Alignment CG31198 and T12E12.6

DIOPT Version :10

• Sequence 1: NP_732654.1
• Gene: CG31198 / 318622
• FlyBaseID: FBgn0051198
• Length: 940
• Species: Drosophila melanogaster
• Sequence 2: NP_500831.2
• Gene: T12E12.6 / 188454
• WormBaseID: WBGene00020465
• Length: 641
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 133/603 - (22%)
• Similarity: 249/603 - (41%)
• Gaps: 99/603 - (16%)

  Fly    46 HITPVNYNITLRPYLLETDGNKRFTFDGEVWIEVISNQTTNDIYLHSKNLTYSVREYWQKPTTEV 110
            :|.|::|::..:..:.|.:|     |.|.:.:....:..:::|.|.:.:| :|.|......:.::
 Worm    21 NIIPLSYDLLFKLPIHEFNG-----FTGSMVLHFNLSSLSDNITLDAVDL-HSFRNISLIRSADL 79

  Fly   111 ANPTVIQISATNTTNYDTDIVKLTASTALTANTTYILHFVYTGLMEDDMHGFYRSSYVDDNNVTK 175
            ..||:..|....      :.|:|....:|......:....|.|.:.:.....:...       ..
 Worm    80 TEPTLKSIKILK------EKVELKFEKSLFPGQYLLTIGEYNGRIGNSSEALFERR-------NP 131

  Fly   176 WLGSTQFQTHHARRAFPSFDEPQFKATFDVTLKRHRTFNSVSNTRLISSYPSTEEGIFS-DVYKT 239
            .|.:|..|.:||||.||..|.|..||.|.:::. |.| ::|:.:..|:.....|...:. .:::.
 Worm   132 LLYTTHLQPNHARRLFPCIDHPAVKALFRLSIV-HPT-DTVAQSNTIAMDVHVENRKWQRTIFQA 194

  Fly   240 TPKMSTYLLAFII---SEFVARKDDDFGVYAR--PEYYAQTQYPYNVGIQILEEMGQYLDKDYYS 299
            ||.:..||:||.:   |.....:...|||..|  .|.........:..:...|.:...:|   ..
 Worm   195 TPLLPAYLVAFSVMPDSNLQLSRQTSFGVTVRVNGESRGLVLRVLDCALASFEILAGLID---VP 256

  Fly   300 MGNDKMDMAAIPDFSAGAMENWGLLTYRERSLLVDESATTLASRQSIAAVVAHEQAHMWFGDLVT 364
            :..:|:|...:|::. |.|||||.:|       |.|:..|......:..::|||.||.|.|:..|
 Worm   257 LPLNKIDFILVPEYD-GGMENWGHIT-------VSETLATSGDDAHLIYLIAHEIAHHWIGNRAT 313

  Fly   365 CKWWSYTWLNEGFARYFQYFGT-AMVEDKWELEKQFVVDQVQSVMAMDSTNATNPLSDENTYTPA 428
            ...|::..|.|....:...... |::.|:..|::..:...|:..:..|..:..:.|     |.|:
 Worm   314 IDSWNWICLQEDLTDWMALKAVKALLTDEIRLQRFQLAQYVEIQLVEDFLSPGHSL-----YMPS 373

  Fly   429 HLSR-MFNSISYNKGATFIRMIKHTMGEQQFQKSLQEYLKKYEYQSSLPEYLLGAWQANWPNSSY 492
            .::: :.|...|.||...:..::..:|||              :..|:.:.|:|:      :|:|
 Worm   374 KINQELINRHCYLKGVVLLDTLESVVGEQ--------------FMYSVIKSLVGS------HSTY 418

  Fly   493 NESSKDIFKSFTEQVGYPLINVTVGN-SQVSFTQKRF--LLKESDGSDSSLKYTV----PISYTT 550
            |.::   |.|:.:|:.... |.|||. .:..:|...:  :|.|::|..|.|:...    |:..|:
 Worm   419 NLTT---FTSYFDQIRVDR-NATVGQIYEYWYTTGGYPSILVENNGPSSRLQQLSRPLWPLKMTS 479

  Fly   551 SETNNFLNTTPKFILKPNVTTTVQFNSTIKWIVVNIQQTGYYRVTYSDDNWHAI------HHALI 609
            :      ...|:|:...::.    |.|....::||:..|.:.||.|....|.||      ...|.
 Worm   480 T------LAIPQFVFSESIV----FASENAPLLVNLNFTSFMRVNYDSLTWTAIFKYMFEEPELF 534

  Fly   610 TANWGGIHENNRAQIVDD 627
            :|       ..|||:|.|
 Worm   535 SA-------VGRAQLVSD 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31198	NP_732654.1	M1_APN-Q_like	50..505	CDD:341064	98/462 (21%)
		ERAP1_C	581..898	CDD:463368	16/53 (30%)
T12E12.6	NP_500831.2	GluZincin	25..402	CDD:472708	88/413 (21%)