DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31198 and aopep

DIOPT Version :9

Sequence 1:	NP_732654.1	Gene:	CG31198 / 318622	FlyBaseID:	FBgn0051198	Length:	940	Species:	Drosophila melanogaster
Sequence 2:	XP_012827019.1	Gene:	aopep / 100145347	XenbaseID:	XB-GENE-986050	Length:	822	Species:	Xenopus tropicalis

Alignment Length:	469	Identity:	96/469 - (20%)
Similarity:	163/469 - (34%)	Gaps:	138/469 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 PTVIQISATNTTNYDTDIVKLTASTALTANTTYILHFVYTGLMEDDMHGFYRSSYVDDNNVTKWL 177
            |:.|:|....|||..:  ||.|...:..       |.|||                        :
Frog   240 PSAIRIWYQTTTNGSS--VKWTKDQSGR-------HCVYT------------------------I 271

  Fly   178 GSTQFQTHHARRAFPSFDEPQFKATFDVTLKRHRTFNSVSNTRLISSYPSTEEGIFSDVYKTTPK 242
            ||    ..:.|..||..:.|...:|:..|::....|..:.:....::..|:.||.||..|..|..
Frog   272 GS----PINNRALFPCQEPPVAMSTWHATIQAACEFVVLMSGENCATPYSSCEGFFSWFYYVTMP 332

  Fly   243 M--STYLLAFIISEFVAR------KDDDFGV-----------------------YARPEYYAQTQ 276
            |  ||:.:|....|.:..      |..|...                       ::.||..||..
Frog   333 MPASTFTIAVGCWEEIKENSSCNIKTSDLSTPLYINNGSRLKEQKCKHMEYPCRFSLPEACAQAI 397

  Fly   277 YPYNVGIQ----------ILEEMGQYLDKDYYSMGN---DKMDMAAIP-DFSAGAMENWGLLTYR 327
            .|:.|...          :|..:...|:..:..:|.   .::|:..:| :||:..|.:..:: |.
Frog   398 IPHRVFASHVLFKQCSEVLLPLVSPCLEAAHAVLGTHPFPRLDILVVPSNFSSLGMASPHII-YL 461

  Fly   328 ERSLLVDESATTLASRQSIAAVVAHEQAHMWFGDLVTCKWWSYTWLNEGFARYFQYFGTAMVEDK 392
            .:|:|       ..|....|..:.||.||.|||.::..:.|:..|::||||.:.:....|.|:
Frog   462 SQSVL-------YGSNHLCATRLCHEIAHAWFGLVIGARDWTEEWISEGFATHLEDVFLANVQ-- 517

  Fly   393 WELEKQFVVDQVQSVMAMDSTNATNPLSD------------ENT-----------YTPAHLSRMF 434
             :|.::...||.:....:.....|:.|.|            |||           ....:..:.|
Frog   518 -KLPQEEARDQQKLKALLRWRRLTDELKDSQEELQILRPHGENTGKVNESGASVVRHGLNAEKTF 581

  Fly   435 NSISYNKGATFIRMIKHTMGEQQFQKSLQEYLKKYEYQSSLPEYLLGAWQANWPNSSYNESSKDI 499
            ..:.|.||...:|.:.:|.|:..:...|::::.....|..|                    |||.
Frog   582 MQVHYLKGYFLLRSLANTTGQDAYFAFLRQFVNTCHGQLIL--------------------SKDF 626

  Fly   500 FKSFTEQVGYPLIN 513
            .....|.|  |.:|
Frog   627 LHMLFESV--PELN 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31198	NP_732654.1	Peptidase_M1	42..442	CDD:279741	81/396 (20%)
		M1_APN_2	50..510	CDD:189008	94/464 (20%)
		ERAP1_C	582..898	CDD:288671
aopep	XP_012827019.1	GluZincin	233..652	CDD:387391	96/469 (20%)
aopep	XP_012827019.1	Leuk-A4-hydro_C	731..821	CDD:378127
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910