DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Slimp and DIA4

DIOPT Version :9

Sequence 1:	NP_732958.1	Gene:	Slimp / 318604	FlyBaseID:	FBgn0051133	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_011875.1	Gene:	DIA4 / 856402	SGDID:	S000001053	Length:	446	Species:	Saccharomyces cerevisiae

Alignment Length:	436	Identity:	92/436 - (21%)
Similarity:	173/436 - (39%)	Gaps:	58/436 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ANENYVTLQPYMDFNKTFGERQFLEQSISSRGLDIRLETVL-------SKYEKYKTHHAQLSKVA 89
            :|.::...:|..|..|........:.||.:|.| |..::::       .:|:..|.....::.:.
Yeast    10 SNRSFFLKKPQFDVKKIIEMIPQYQTSIQNREL-IEADSIIRSLQLLGERYQNIKEIDKVIADIQ 73

  Fly    90 EERERVTKRL-KELTKSGSSAVQLEELKEHGKSLRNELKALKQTLYPIEDDFIHDYLHLPNLLHV 153
            .:|:.:..:: |:.||....:..|:.|||......::...||:.:       :.....|||.|..
Yeast    74 IQRKSIEAQIKKDKTKITEYSAALKALKEQYNDQNSKSSELKKKI-------LETCKSLPNTLDP 131

  Fly   154 QCPVGGEEKLLYRHGIPKSENKTTSHLARQELV------------HFVDNNRYYLMEQAALFDVN 206
            ..|:...:  :.:...|...:||:...|..:::            :....:.|||:...|..:
Yeast   132 TVPLDAPQ--IEQWINPLKTHKTSEAQAHVDIMLKKNMLDLQTASNVTGMSWYYLLNDGARLE-- 192

  Fly   207 AMQSLARYFV---NHGHFIQTANPDFVRCVLLEA---NATPLSD---YHLVQEEHLQNKINTAY- 261
              |:|..|.:   |...|.....|...:..|::|   |...:::   .:.:|:.:| ..:.||.
Yeast   193 --QALVAYALKKANENGFSSCVPPSITKKELIDACGFNPRDMNNERQIYALQDTNL-GLVATAEI 254

  Fly   262 -LTGGASFESYLGAMTKLCVYPSVLPLRYVCCGRSYNRAEADLYG-PIPSLYTATQTNAVQIFVA 324
             |.|       |||...|.:.......:.|...|.| ||||...| ....||...:...|::|..
Yeast   255 PLAG-------LGANKVLELNSGECSKKLVGVSRCY-RAEAGARGKDTKGLYRVHEFTKVELFCW 311

  Fly   325 TQTDNEADSQLEHILNLATDFYKALDIPFRISYATAADLTPAESIRAVIEVYAPSLQRYVCVGRI 389
            ::.:..| ..||.|........:.|.||.::....:.||......:..||.:.|...::..:...
Yeast   312 SKPETSA-KVLEEIKQFQISVVEELGIPAKVLNMPSNDLGNPAFKKYDIEAWMPGRGKFGEISSA 375

  Fly   390 SNYGDFVSKRILFSTRREK--HYDFLHMVGGPVLYTSRLIAALVEH 433
            ||..||.|:|:....|.:.  ..:::|.:.|..:...|:|.||||:
Yeast   376 SNCTDFQSRRLNTKYRDDNTGKLEYVHTLNGTAMAIPRVIVALVEN 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slimp	NP_732958.1	serS	43..433	CDD:273066	89/423 (21%)
		Seryl_tRNA_N	51..150	CDD:299883	19/106 (18%)
		class_II_aaRS-like_core	194..433	CDD:294192	61/252 (24%)
DIA4	NP_011875.1	serS	1..440	CDD:273066	92/436 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344389
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0172
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11778
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.800