Protein Alignment Wsck and flt3

DIOPT Version :9

• Sequence 1: NP_733018.1
• Gene: Wsck / 318600
• FlyBaseID: FBgn0046685
• Length: 791
• Species: Drosophila melanogaster
• Sequence 2: XP_001921760.3
• Gene: flt3 / 566708
• ZFINID: ZDB-GENE-050114-4
• Length: 956
• Species: Danio rerio
• Alignment Length: 838
• Identity: 161/838 - (19%)
• Similarity: 299/838 - (35%)
• Gaps: 225/838 - (26%)

  Fly    45 CYTARTDLLHESVYAKTP-----------QTCIEICEHQGHHYAVLASEKCFCANVLEPQEQQDE 98
            |.|..|.:.:.|..:|.|           :.|.|:     :||.:....|....|::..:..|..
Zfish   170 CKTESTLISYYSYLSKNPNQKCCASNALGEECTEV-----YHYDLNEKNKQKSQNIIYLKSGQSL 229

  Fly    99 QLCNTRCLANKAQYCGGVGVHSYYSTILTKQPGPHHLRISNKTENSLTLSWNAYEARKLLLAGGA 163
            .|...|      ::....|:..:::..:.|  |...|:..:.||:....|.|...:...|.....
Zfish   230 LLRAAR------KHFKNPGIKWHFNNTVIK--GITSLQFYDWTEHLFIESVNMAHSGLYLCTSDT 286

  Fly   164 EAVLPN------QLLDNFLIKAQVLKTYSSLPAFPQPEFMVQSTETQFELTDLHPATLYNISVRA 222
            |.  |.      ::.::..|....|...:|:.|..:..|..||....:.              :|
Zfish   287 ET--PRNCSTHVKVFEHDQIDILHLNENNSILAKNKTGFCFQSQVFSYP--------------KA 335

  Fly   223 MC-----KDAQVGQSECGQASIEATTEVGLPSPVPAQPKILSRTDRTVTIELSPIRNDNGPLSKL 282
            .|     ...|:...|..|::..:|.::....|...|.|:       .|.|.|.:||.:..:|.:
Zfish   336 RCYWITPNQTQIQCDETSQSNFTSTFKLCNTEPGQYQMKL-------ETQEYSVMRNVSLCISDI 393

  Fly   283 LVIV-----EYVDNALSQPFDAQLLGSWQQ----AQQDGVPYYIAAELDYDRPEDNRTRRFVVGD 338
            ..|.     .:.......|....:  ||:.    |:.|...:   .|:..|:||...:.:|.
Zfish   394 PKITIRKNSSFTTCETESPLPVTV--SWKTCPSLAKCDPEDW---KEIAADQPEFTDSDQFC--- 450

  Fly   339 GKRYGRFTNKPLDQPDAHVHISLGLVSTLEGVTKTMYSRGTHDQHVTSLDDFSYATFEKGQSSVV 403
            .|:.| |:.:.|...|   |:....::.:.|.       |..::.:......:|        .|:
Zfish   451 QKKIG-FSRRHLKSED---HLIKCCITNVAGT-------GCSEKILLQTKSHTY--------YVI 496

  Fly   404 ALAVTCVIFGSCLLLSLIAYFYLRYKTCRGRRLTGGNTHEMTLQ-TPIIERENNGYLVEDDPLPH 467
            ...:..::|  .::::||  .::|.|..:         ::..:| ..:|...:|.|:..|.
Zfish   497 CFLLIVILF--MIIIALI--IFIRVKKPK---------YQSQIQMIQMIGPNDNDYIYIDF---- 544

  Fly   468 SPENFKQQLQQLVEGYERIPRNALRLNVNDVIGDGRFGEIITGK---VSTNDFARDCTLHVLCLD 529
              ..||..|:.      ..||..|.|  .:.:|.|.||.::...   :|....:....:.:| .:
Zfish   545 --REFKYDLKW------EFPRENLEL--GNELGSGAFGMVVQATAYGISKPGVSVQVAVKML-KE 598

  Fly   530 DLNGTTQAQLLRELRQLSQLKRQEHLLDFYGVSASPDWFYLI----------------------- 571
            ......:..|:.||:.|:.:...|::::..|........|||
Zfish   599 KHQAVEKEALMSELKMLTHIGHHENIVNLLGACTGSGPIYLIFQFCCNGDLLNYLKSNRECFHKY 663

  Fly   572 ----------------FEQQRMSLK-----------------------RKLVESRLMAPSP---- 593
                            |:|.|.|.:                       ..|:.|.:.:.||
Zfish   664 LTDAFNKDRFRGLYHNFQQNRNSSEYVLSDNSQCLNVTPASKEQENENDALLSSSISSGSPAEEM 728

  Fly   594 ----------RLTSLSEQLVLQWIYELASAMNYLSSCQVVHRQLCSHSVFVTSDFKLKLSVFGPL 648
                      .|.||:...:|.:.:::|..|.:||:...:||.|.:.:|.||...::|::.||
Zfish   729 LECEDEHQEEELHSLTYDDLLSFSFQVAKGMQFLSAKNCIHRDLAARNVLVTHGRQVKIADFG-- 791

  Fly   649 PYMNIARQ-QPDHN-----------RWLAPEVLRHQHHHSTRSDVWSLACVAWECCALGGTPYAN 701
                :||. :.|.|           :|:|||.: .:..::..||:|:...:.||..:||.|||.
Zfish   792 ----LARDIEHDSNYVVRGNVRLPVKWMAPESI-FKGIYTMESDIWAYGILLWEIFSLGVTPYP- 850

  Fly   702 AVASNQQLLEAIRAAVRPAQPAYVYGDLYQLLLNCWQLEPSERSSC--EDVAFGVRQL 757
            .|..|......|.:.....||.|....:|:::..||.|.|.:| .|  :.|||..::|
Zfish   851 GVTVNNTFYRMIESGYHLEQPYYAAESVYKVMCRCWALNPVDR-PCFSKIVAFMEKEL 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wsck	NP_733018.1	WSC	42..115	CDD:280068	15/80 (19%)
		fn3	130..222	CDD:278470	16/97 (16%)
		TyrKc	493..746	CDD:197581	71/343 (21%)
		PTKc	497..750	CDD:270623	71/345 (21%)
flt3	XP_001921760.3	IGc2	225..283	CDD:197706	12/65 (18%)
		PKc_like	522..907	CDD:328722	86/408 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900