DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wsck and si:ch73-206d17.1

DIOPT Version :9

Sequence 1:	NP_733018.1	Gene:	Wsck / 318600	FlyBaseID:	FBgn0046685	Length:	791	Species:	Drosophila melanogaster
Sequence 2:	XP_689652.2	Gene:	si:ch73-206d17.1 / 561155	ZFINID:	ZDB-GENE-090313-143	Length:	393	Species:	Danio rerio

Alignment Length:	383	Identity:	81/383 - (21%)
Similarity:	157/383 - (40%)	Gaps:	83/383 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   393 ATFEKGQSSVVALAVTCVI-FGSCLLLSLIAYFYLRYKTCRGRRLTGGNTHEMTLQTPIIERENN 456
            |.:::|...:..:.:..:: ..:.:::|.|.:.::. |....:::|..:::       :.|||:
Zfish    16 ACYDEGSGPLAVIIIPSLLALSTLIVVSQIIWSFVT-KRSSAQKITSSSSN-------VNEREH- 71

  Fly   457 GYLVEDDPLPHS--PEN----FKQQLQQLVEGYERIPRNALRLNVNDVIGDGRFGEIITGKVSTN 515
               |:.|....|  |.|    .:..:|..:||.|             |:..||:|.|..|::..:
Zfish    72 ---VQLDAGIGSLRPANVLGPLELPVQCTLEGVE-------------VLQMGRYGPICMGQLKQD 120

  Fly   516 DFARDCTLHVLCLDDLNGTTQAQLLRELRQLSQLKRQEHLLDFY----GVSASPDWFYLIFEQQR 576
            :                 |:.|.:::.|:..|........:|..    .||...:...|:|.|.|
Zfish   121 N-----------------TSTAVMIKTLKDRSTQSESAEFMDLVLFHAAVSKHENIVKLLFCQTR 168

  Fly   577 MSLKRKLVESRLMAPSPRLTSL--------------SEQLVLQWIYELASAMNYL-SSCQVVHRQ 626
            .:....|:|:.:  |...|..|              ||:.|.....::|:.::|| |..:|:|..
Zfish   169 RTPMYLLLEASV--PGNLLNFLWSLREDRCGESSVFSEKSVFLVAKQIAAGLDYLHSHHRVIHGD 231

  Fly   627 LCSHSVFVTSDFKLKLS----VFGPLPYMNIARQQPDHN---RWLAPEVLRHQHHHSTRSDVWSL 684
            :.:.::.:.|.|.:|:|    .|.......:.|:| :.|   :|.|||.:. :...:.||||||.
Zfish   232 VAARNMLIGSAFSVKVSGLDFAFESRQKKKVDREQ-EANVPVKWQAPERMM-RLPLTDRSDVWSF 294

  Fly   685 ACVAWECCALGGTPYANAVASNQQLLEAIRAAVRPAQPAYVYGDLYQLLLNC--WQLE 740
            ..:.:|...||..||.:...|  ::|....|..|..:|......|:.|:..|  |..:
Zfish   295 GILLYEMITLGSPPYPDLDPS--EVLPRTLAHYRMKRPENCGAPLFDLIKYCCMWNFK 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wsck	NP_733018.1	WSC	42..115	CDD:280068
		fn3	130..222	CDD:278470
		TyrKc	493..746	CDD:197581	63/276 (23%)
		PTKc	497..750	CDD:270623	63/272 (23%)
si:ch73-206d17.1	XP_689652.2	PKc_like	102..363	CDD:304357	64/285 (22%)
si:ch73-206d17.1	XP_689652.2	Pkinase_Tyr	102..362	CDD:285015	64/285 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900