DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wsck and Fgfrl1

DIOPT Version :9

Sequence 1:	NP_733018.1	Gene:	Wsck / 318600	FlyBaseID:	FBgn0046685	Length:	791	Species:	Drosophila melanogaster
Sequence 2:	NP_954545.1	Gene:	Fgfrl1 / 360903	RGDID:	735156	Length:	529	Species:	Rattus norvegicus

Alignment Length:	204	Identity:	44/204 - (21%)
Similarity:	77/204 - (37%)	Gaps:	56/204 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 LKTYSSLPAFPQPEFM---VQSTETQFELTDLHPATLYNISVRAMCKDAQVGQSEC----GQASI 239
            ||..:|  ..|:|:.|   ...|.|:.|.:: |....:.:|::.: |....|:..|    ...:|
  Rat   166 LKCVAS--GHPRPDIMWMKDDQTLTRLEASE-HRKKKWTLSLKNL-KPEDSGKYTCRVSNRAGAI 226

  Fly   240 EATTEVGLPSPVPAQPKILSRTDRTVTIELS-------PIRNDNGPLSKLLVIVEYVDNALSQPF 297
            .||.:|.:.....::|.:........|::..       .:|:|..|:.:.|..|||
  Rat   227 NATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEY--------- 282

  Fly   298 DAQLLGSWQQAQQDGVPYYIAAELDYDRPEDNRTRRFVV---GD--GKRYGRFTNKPL----DQP 353
                                .:|..::...|...::|||   ||  .:..|.:.||.|    .|.
  Rat   283 --------------------GSEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLISRARQD 327

  Fly   354 DAHVHISLG 362
            ||.::|.||
  Rat   328 DAGMYICLG 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wsck	NP_733018.1	WSC	42..115	CDD:280068
		fn3	130..222	CDD:278470	11/42 (26%)
		TyrKc	493..746	CDD:197581
		PTKc	497..750	CDD:270623
Fgfrl1	NP_954545.1	I-set	29..112	CDD:400151
		Ig strand A'	35..38	CDD:409353
		Ig strand B	41..50	CDD:409353
		Ig strand C	56..61	CDD:409353
		Ig strand C'	64..67	CDD:409353
		Ig strand D	72..77	CDD:409353
		Ig strand E	78..84	CDD:409353
		Ig strand F	91..99	CDD:409353
		Ig strand G	102..112	CDD:409353
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	117..152
		IgI_2_FGFRL1-like	143..234	CDD:409442	18/71 (25%)
		Ig strand B	164..168	CDD:409442	1/1 (100%)
		Ig strand C	177..181	CDD:409442	1/3 (33%)
		Ig strand E	200..204	CDD:409442	0/3 (0%)
		Ig strand F	214..219	CDD:409442	1/4 (25%)
		Ig strand G	227..230	CDD:409442	1/2 (50%)
		Ig	242..350	CDD:416386	26/124 (21%)
		Ig strand A	242..245	CDD:409353	1/2 (50%)
		Ig strand A'	249..253	CDD:409353	0/3 (0%)
		Ig strand B	261..268	CDD:409353	0/6 (0%)
		Ig strand C	272..279	CDD:409353	2/6 (33%)
		Ig strand D	304..309	CDD:409353	2/4 (50%)
		Ig strand E	317..322	CDD:409353	3/4 (75%)
		Ig strand F	330..338	CDD:409353	3/7 (43%)
		Ig strand G	341..349	CDD:409353
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	405..427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900