DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wsck and Ptprf

DIOPT Version :9

Sequence 1:NP_733018.1 Gene:Wsck / 318600 FlyBaseID:FBgn0046685 Length:791 Species:Drosophila melanogaster
Sequence 2:XP_038966081.1 Gene:Ptprf / 360406 RGDID:3453 Length:1928 Species:Rattus norvegicus


Alignment Length:514 Identity:98/514 - (19%)
Similarity:181/514 - (35%) Gaps:124/514 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 PQEAPAYY-----YVGCYTARTDLLHESVYAKTPQTCIEICEHQGH--HYAVL---ASEKCFCAN 88
            |::||:.:     ..|..|:.|:|      |..|..   :.|..|.  :|.|:   .:.:....|
  Rat   921 PEDAPSGFPQNLRVTGLTTSTTEL------AWDPPV---LAERNGRITNYTVVYRDINSQHELQN 976

  Fly    89 V----------LEPQEQQDEQLCNTRCLANKAQYCGGVGVHSYYSTILTKQPGPHHLRISNKTEN 143
            |          |:|....|     .:..|:.::..|.:.......|:..:|....:.|::...:.
  Rat   977 VTGDVHLTLLGLKPDTTYD-----IKVRAHTSKGAGPLSPSIQSQTMPMEQVFAKNFRVAAAMKT 1036

  Fly   144 SLTLSWNAYEARKLLLAGGAEAVLPNQLLDNFLIKAQVLKTYSSLPAFPQPEFMVQSTETQFE-- 206
            |:.|||...::.|        :.:|.::|.|                       .||.|....  
  Rat  1037 SVLLSWEVPDSYK--------SAVPFKILYN-----------------------GQSVEVDGHSM 1070

  Fly   207 ---LTDLHPATLYNISVRAMCKDAQVGQSECGQASIEATTEVGLPSPVPAQPKILSRTDRTVTIE 268
               :.||.|.|.|:..:  |.:.:..|..: ...||....::....|:||...|   .|...::.
  Rat  1071 RKLIADLQPNTEYSFVL--MNRGSSAGGLQ-HLVSIRTAPDLLPQKPLPASAFI---EDGRFSLS 1129

  Fly   269 LSPIRNDNGPLSKLLVIVEYVD----NALSQPFDA-------QLLGSWQQA---------QQDGV 313
            :..:: |...:....::|..:|    |.|:..:..       :||.:.:|.         |.:.:
  Rat  1130 MPQVQ-DPSLVRWFYIVVVPIDRVGGNLLAPRWSTPEELELDELLEAIEQGEEKQRRRRRQAERL 1193

  Fly   314 PYYIAAELDYDRPEDNRTRRFVVGDGKRYGRFTNKPLDQPDAHVHISLGLVSTLEGVTKTMYSRG 378
            ..|:||::| :.||     .|.:||.|.|..|.|:|| .||......: |.|..|.:.:..|:..
  Rat  1194 KPYVAAQVD-ELPE-----TFTLGDKKNYRGFYNRPL-SPDLSYQCFV-LASLKEPMDQKRYASS 1250

  Fly   379 THDQHVTSLDDFSYATFEKGQSSVVALAVTCVIFGSCLLLSLIAYFYLRYKTCRGRRLTGGNTHE 443
            .:...:.     ...|..:.|.....|.||..:. :.:|:.||....|.:|..|....:..:...
  Rat  1251 PYSDEIV-----VQVTPAQQQEEPEMLWVTGPVL-AVILIILIVIAILLFKRKRTHSPSSKDEQS 1309

  Fly   444 MTLQTPI-------IERENNGYLVEDDPLPHSPENFKQQ------LQQLVEGYERIPRN 489
            :.|:..:       :|.....|.......|..|.....:      :..|.:..||:..|
  Rat  1310 IGLKDSLLAHSSDPVEMRRLNYQTPGSSAPSCPNISSMRDHPPIPITDLADNIERLKAN 1368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
WsckNP_733018.1 WSC 42..115 CDD:280068 16/87 (18%)
fn3 130..222 CDD:278470 17/96 (18%)
TyrKc 493..746 CDD:197581
PTKc 497..750 CDD:270623
PtprfXP_038966081.1 I-set 33..124 CDD:400151
Ig strand A 33..36 CDD:409353
Ig strand A' 42..45 CDD:409353
Ig strand B 50..57 CDD:409353
Ig strand C 63..68 CDD:409353
Ig strand C' 71..73 CDD:409353
Ig strand D 80..84 CDD:409353
Ig strand E 86..93 CDD:409353
Ig strand F 103..111 CDD:409353
Ig strand G 114..124 CDD:409353
IgI_2_RPTP_IIa_LAR_like 136..232 CDD:409400
Ig strand B 152..156 CDD:409400
Ig strand C 165..169 CDD:409400
Ig strand E 196..200 CDD:409400
Ig strand F 210..215 CDD:409400
Ig strand G 222..225 CDD:409400
IgI_3_RPTP_IIa_LAR_like 245..326 CDD:409401
Ig strand B 259..263 CDD:409401
Ig strand C 272..276 CDD:409401
Ig strand E 293..297 CDD:409401
Ig strand F 305..310 CDD:409401
Ig strand G 318..321 CDD:409401
FN3 329..418 CDD:238020
FN3 425..517 CDD:238020
FN3 522..611 CDD:238020
FN3 619..713 CDD:238020
FN3 720..826 CDD:238020
FN3 831..920 CDD:238020
FN3 929..1017 CDD:238020 17/101 (17%)
FN3 1026..>1085 CDD:238020 17/89 (19%)
PTP_DSP_cys 1356..1631 CDD:421693 4/13 (31%)
R-PTP-F-2 1633..1923 CDD:350477
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4228
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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