DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wsck and Ptp36E

DIOPT Version :9

Sequence 1:	NP_733018.1	Gene:	Wsck / 318600	FlyBaseID:	FBgn0046685	Length:	791	Species:	Drosophila melanogaster
Sequence 2:	NP_001286033.1	Gene:	Ptp36E / 35091	FlyBaseID:	FBgn0267486	Length:	682	Species:	Drosophila melanogaster

Alignment Length:	252	Identity:	46/252 - (18%)
Similarity:	83/252 - (32%)	Gaps:	123/252 - (48%)

- Green bases have known domain annotations that are detailed below.

  Fly   456 NGYLVEDDPLPHSPENFKQQLQQLVEGYERIPRNALRLNVNDVIGDGRFGEIITGKVSTNDFARD 520
            |.|:|...|           :::.|:.|.|:   ..:.|::.::       ::|   .|.|||:
  Fly   168 NAYIVTQGP-----------VEETVQAYWRM---VWQENISAIV-------MLT---KTFDFAK- 207

  Fly   521 CTLHVLC---------LDDLNGTTQAQLLRELRQLSQLKRQEHLLDFYGVSASPDWFYLIFEQQR 576
                |:|         :.:..|.....::||          |.|.:|:         ...|...:
  Fly   208 ----VMCHQYWPPNMEVHEQYGDIFINIVRE----------EQLANFH---------IRTFRLYK 249

  Fly   577 MSLKRKLVESRLMAPSPRLTSLSEQLVLQWIYELASAMNYLSSCQ-------------------- 621
            |:.|:::.:              |:|:||:.|    ...|..||.
  Fly   250 MNEKQEVTD--------------ERLILQFHY----TEWYSHSCPFSNALLEFRRRVRLVVGNII 296

  Fly   622 ----------VVHRQLCS-----HSVFVTSDFKLKL-------SVFGPLPYMNIARQ 656
                      :||   ||     ..|:::.|..|:|       :|||   |:...||
  Fly   297 KDEDDMRGPILVH---CSDGGGRSGVYMSIDANLELAEEEECFNVFG---YLKKLRQ 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wsck	NP_733018.1	WSC	42..115	CDD:280068
		fn3	130..222	CDD:278470
		TyrKc	493..746	CDD:197581	39/215 (18%)
		PTKc	497..750	CDD:270623	38/211 (18%)
Ptp36E	NP_001286033.1	Y_phosphatase	125..368	CDD:395053	46/252 (18%)
Ptp36E	NP_001286033.1	Y_phosphatase	428..671	CDD:395053
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4228
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900