Protein Alignment Wsck and Csf1r

DIOPT Version :10

• Sequence 1: NP_733018.1
• Gene: Wsck / 318600
• FlyBaseID: FBgn0046685
• Length: 791
• Species: Drosophila melanogaster
• Sequence 2: NP_001424441.1
• Gene: Csf1r / 307403
• RGDID: 2425
• Length: 978
• Species: Rattus norvegicus
• Alignment Length: 761
• Identity: 152/761 - (19%)
• Similarity: 261/761 - (34%)
• Gaps: 260/761 - (34%)

  Fly   122 YSTILTKQPGPHHLRISNKTENSLTLSWNAYEARKLLLAGGAEAVLPNQLLDNFLIKAQVLKTYS 186
            ||.:.....|          .|:.|:::...|:..|.|. ..:::|....:...|....:...|.
  Rat   276 YSCVANNAAG----------SNTATMNFQVVESAYLNLT-SEQSLLQEVSVGENLDLTVIADAYP 329

  Fly   187 SL---------PAFPQP---EFMVQSTETQFELTDLHPATLYNISVRAMCKDAQVGQSECG---- 235
            .|         |.|..|   ||..|.|...:.. .||   |..:......:.:.:.|::.|
  Rat   330 GLQRYNWTYLGPFFEDPHNLEFRTQWTTYSYSF-KLH---LNRVKPLEAGRYSLMAQNKAGWNNL 390

  Fly   236 --QASIEATTEV------------------GLPSPVPAQPKILSRTDRTVTIELSPIRNDNGPLS 280
              :.::....||                  |.|.|.....:....|||....:.|.:.:|..|
  Rat   391 TFELTLRYPPEVSVTWIPVNGSDVLLCDVSGYPQPNVTWMECRGHTDRCDEAQASQVWDDTQP-- 453

  Fly   281 KLLVIVEYVDNALSQ-PFDAQLLGSWQQAQQDGVPY--------YIAAELDYDRPEDNRTRRFVV 336
                      ..||| ||...:|       |..:|.        |:.      |..:|      |
  Rat   454 ----------EVLSQKPFHRVIL-------QSQLPIGTLKHNMTYVC------RAHNN------V 489

  Fly   337 GDGKRYGRFTNKPLDQPDAHVHISLGLVSTLEGVTKTMYSRGTHDQHVTSLDDFSYATFEKGQSS 401
            |:..::.|             .||||            .|:...|:::
  Rat   490 GNSSQFFR-------------AISLG------------QSKQLPDEYL----------------- 512

  Fly   402 VVALAVTCVIFGSCLLLSLIAYFYLRYKTCRGRRLTGGNTHEMTLQTPIIER-ENNGY-LVEDDP 464
            ...:.|.|:...|.|:|.|:...| :||          ...:..::..|||. |.|.| .::...
  Rat   513 FTPVVVACISVMSLLVLLLLLLLY-KYK----------QKPKYQVRWKIIESYEGNNYTFIDPTQ 566

  Fly   465 LPHSPENFKQQLQQLVEGYERIPRNALRLNVNDVIGDGRFGEII------TGKVSTNDFARDCTL 523
            ||::            |.:| .|||  .|.....:|.|.||:::      .||       .|..|
  Rat   567 LPYN------------EKWE-FPRN--NLQFGKTLGAGAFGKVVEATAFGLGK-------EDAVL 609

  Fly   524 HVLCLDDLNGTTQAQ----LLRELRQLSQLKRQEHLLDFYGV----------------------- 561
            .| .:..|..|..|.    |:.||:.:|.|.:.|::::..|.
  Rat   610 KV-AVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVITEYCCYGDLLNFL 673

  Fly   562 ----------SASP------DWFYLIFEQQRMSLKR----------KLVESRLMAPSPRLTSLSE 600
                      |.||      |..|.....::..::|          ..||.|.::.|...:...:
  Rat   674 RRKAEAMLGPSLSPGQDPEGDSSYKNIHLEKKYVRRDSGFSSQGVDTYVEMRPVSTSSNDSFFKQ 738

  Fly   601 QL------------VLQWIYELASAMNYLSSCQVVHRQLCSHSVFVTSDFKLKLSVFGPLPYMNI 653
            .|            :|.:..::|..|.:|:|...:||.:.:.:|.:||....|:..||      :
  Rat   739 DLDKEASRPLELWDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTSGHVAKIGDFG------L 797

  Fly   654 ARQ-QPDHN-----------RWLAPEVLRHQHHHSTRSDVWSLACVAWECCALGGTPYANAVASN 706
            ||. ..|.|           :|:|||.: ....::.:|||||...:.||..:||..||...:.:|
  Rat   798 ARDIMNDSNYVVKGNARLPVKWMAPESI-FDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNN 861

  Fly   707 QQLLEAIRAAVRPAQPAYVYGDLYQLLLNCWQLEPSERSSCEDVAF 752
             :..:.::...:.|||.:...::|.::.:||.|||::|.:.:.:.|
  Rat   862 -KFYKLVKDGYQMAQPVFAPENIYSIMQSCWDLEPTKRPTFQQICF 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wsck	NP_733018.1	WSC	42..115	CDD:460348
		fn3	130..222	CDD:394996	20/103 (19%)
		PTKc	497..750	CDD:270623	73/335 (22%)
Csf1r	NP_001424441.1	None