Sequence 1: | NP_733018.1 | Gene: | Wsck / 318600 | FlyBaseID: | FBgn0046685 | Length: | 791 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_004110.2 | Gene: | FLT3 / 2322 | HGNCID: | 3765 | Length: | 993 | Species: | Homo sapiens |
Alignment Length: | 421 | Identity: | 90/421 - (21%) |
---|---|---|---|
Similarity: | 153/421 - (36%) | Gaps: | 121/421 - (28%) |
- Green bases have known domain annotations that are detailed below.
Fly 413 GSCLLLSLIAYFYLRYKTCRGRRLTGGNTHEMTLQ-TPIIERENNGYLVEDDPLPHSPENFKQQL 476
Fly 477 QQLVEGYE-----RIPRNALRLNVNDVIGDGRFGEIITGK---VSTNDFARDCTLHVLCLDDLNG 533
Fly 534 TTQAQLLRELRQLSQLKRQEHLLDFYGVSASPDWFYLIFE------------QQRMSLKRKLVE- 585
Fly 586 ----------------------SRLMAPSPRLTSLS------------------------EQL-- 602
Fly 603 -----VLQWIYELASAMNYLSSCQVVHRQLCSHSVFVTSDFKLKLSVFGPLPYMNIARQ-QPDHN 661
Fly 662 -----------RWLAPEVLRHQHHHSTRSDVWSLACVAWECCALGGTPYANAVASNQQLLEAIRA 715
Fly 716 AVRPAQPAYVYGDLYQLLLNCWQLEPSERSS 746 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Wsck | NP_733018.1 | WSC | 42..115 | CDD:280068 | |
fn3 | 130..222 | CDD:278470 | |||
TyrKc | 493..746 | CDD:197581 | 72/333 (22%) | ||
PTKc | 497..750 | CDD:270623 | 72/331 (22%) | ||
FLT3 | NP_004110.2 | ig | 256..345 | CDD:278476 | |
PKc_like | 572..947 | CDD:304357 | 84/392 (21%) | ||
Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of bound ligand | 591..597 | 2/22 (9%) | |||
Pkinase_Tyr | 610..943 | CDD:285015 | 73/335 (22%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |