DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Wsck and Ptprd

DIOPT Version :9

Sequence 1:NP_733018.1 Gene:Wsck / 318600 FlyBaseID:FBgn0046685 Length:791 Species:Drosophila melanogaster
Sequence 2:XP_036019731.1 Gene:Ptprd / 19266 MGIID:97812 Length:1966 Species:Mus musculus


Alignment Length:572 Identity:112/572 - (19%)
Similarity:186/572 - (32%) Gaps:199/572 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 AVPQEAPAYYYVGCYTARTDLLHESVYAKTPQTCIE-------ICEHQG--HHYAVLASEKCFCA 87
            :||:|.|        |.....||..   .|..|.::       :.|..|  ..|.:|..:    .
Mouse   920 SVPEEIP--------TGFPQNLHSE---GTTSTSVQLSWQPPVLAERNGVITKYTLLYRD----I 969

  Fly    88 NV-LEPQEQ----QDEQLCNTRCLANKAQYCGGVGVHSYYSTILTKQPGPH-------------- 133
            || |.|.|.    .|..:..|. |.:...|...|..|:      :|.|||:              
Mouse   970 NVPLLPMEHLIVPADTSMTLTG-LKSDTTYDVKVRAHT------SKGPGPYSPSVQFRTLPVDQA 1027

  Fly   134 ------HLRISNKTENSLTLSWNAYEARKLLLAGGAEAVLPNQLL--DNFLIKAQVLKTYSSLPA 190
                  |::...||  |:.|||...|        ...:.:|.::|  |..:::.           
Mouse  1028 VFAKNFHVKAVMKT--SVLLSWEIPE--------NYNSAMPFKILYDDGKMVEE----------- 1071

  Fly   191 FPQPEFMVQSTETQFELTDLHPATLYNISVRAMCKDAQVGQSECG-QASIEATTEVGLPSPVPAQ 254
                   |....||..:.:|.|...|:..:      ...|.|..| |..:.|.|   .|..:..:
Mouse  1072 -------VDGRATQKLIVNLKPEKSYSFVL------TNRGNSAGGLQHRVTAKT---APDVLRTK 1120

  Fly   255 PKILSRT--DRTVTIELSPIRNDNGPLSKLLVIVEYVDNALSQPFDAQLLGSWQQAQQDGVPYYI 317
            |..:.:|  |..:|::|..:..:.......::||....:.      .:.:..|:...:       
Mouse  1121 PAFIGKTNLDGMITVQLPDVPANENIKGYYIIIVPLKKSR------GKFIKPWESPDE------- 1172

  Fly   318 AAELDYDRPEDNRTRR------------------------FVVGDGKRYGRFTNKPLDQPDAHVH 358
             .|||....|.:|.||                        |.:||.|.||.||||.|.....:|.
Mouse  1173 -MELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVF 1236

  Fly   359 ISLGLVSTLEGVTKTMYSRGTHDQHVTSLD-DFSYATFEKGQSSVVALAVTCVIFGSCLLLSLIA 422
            ..|.::...|   ..||:...:...|.|:| |....|.|:.....|...|..|:|..|:::::  
Mouse  1237 FVLAVMDHAE---SKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAI-- 1296

  Fly   423 YFYLRYKTCR---------GRRLTGGNTHE--------------MTLQTPIIERENNGY------ 458
               |.||:.:         .|:.:..|:.|              :..|||.:...:..|      
Mouse  1297 ---LLYKSSKPDRKRAESESRKSSLPNSKEVPSHHPTDPVELRRLNFQTPALSSNSVPYASLIGS 1358

  Fly   459 ------------LVEDDPLP---------HSPENFKQQLQQLVEGYERIPRN 489
                        :.:::.||         |.|    ..:.:|.:..||:..|
Mouse  1359 VSSLSSQTTTQSIYDNNSLPRFARKGMASHPP----IPILELADHIERLKAN 1406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
WsckNP_733018.1 WSC 42..115 CDD:280068 18/86 (21%)
fn3 130..222 CDD:278470 20/113 (18%)
TyrKc 493..746 CDD:197581
PTKc 497..750 CDD:270623
PtprdXP_036019731.1 I-set 31..123 CDD:400151
Ig strand A' 39..43 CDD:409353
Ig strand B 46..55 CDD:409353
Ig strand C 61..66 CDD:409353
Ig strand C' 69..72 CDD:409353
Ig strand D 75..83 CDD:409353
Ig strand E 84..94 CDD:409353
Ig strand F 102..110 CDD:409353
Ig strand G 113..123 CDD:409353
IgI_2_RPTP_IIa_LAR_like 135..234 CDD:409400
Ig strand B 151..155 CDD:409400
Ig strand C 164..168 CDD:409400
Ig strand E 198..202 CDD:409400
Ig strand F 212..217 CDD:409400
Ig strand G 224..227 CDD:409400
IgI_3_RPTP_IIa_LAR_like 247..328 CDD:409401
Ig strand B 261..265 CDD:409401
Ig strand C 274..278 CDD:409401
Ig strand E 295..299 CDD:409401
Ig strand F 307..312 CDD:409401
Ig strand G 320..323 CDD:409401
FN3 331..420 CDD:238020
FN3 427..519 CDD:238020
FN3 524..612 CDD:238020
FN3 620..714 CDD:238020
FN3 721..827 CDD:238020
FN3 832..927 CDD:238020 4/14 (29%)
FN3 930..1021 CDD:238020 23/104 (22%)
FN3 1031..>1092 CDD:238020 17/88 (19%)
R-PTPc-D-1 1388..1671 CDD:350472 6/23 (26%)
R-PTP-D-2 1672..1963 CDD:350476
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4228
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.