DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wsck and R09D1.13

DIOPT Version :9

Sequence 1:	NP_733018.1	Gene:	Wsck / 318600	FlyBaseID:	FBgn0046685	Length:	791	Species:	Drosophila melanogaster
Sequence 2:	NP_496022.1	Gene:	R09D1.13 / 187740	WormBaseID:	WBGene00011169	Length:	388	Species:	Caenorhabditis elegans

Alignment Length:	381	Identity:	85/381 - (22%)
Similarity:	153/381 - (40%)	Gaps:	62/381 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   405 LAVTCVIFGSCLLLSLIAYFYLRYK--------TCRGRRLTGGNTHEMTLQTPIIE-----RENN 456
            |.:...||.:.:|.:........||        ..||:|  |..|.::.| |||.:     |:|
Worm     5 LVILICIFIAVILFAFACILQKVYKKKTQDRPALRRGKR--GSITEQIEL-TPINKDDMCIRDN- 65

  Fly   457 GYLVEDDPLPHSPENFKQQLQQLVEGYERIPRNALRLNVNDVIGDGRFGEIITGKVSTNDFARDC 521
             ..:.:.|:...|.|.|                     .:.|:.:|.|.:|..|.::.|..|.:.
Worm    66 -ISIGNIPVEIDPSNLK---------------------FSSVLENGYFCKIRRGTLNINVTAEEK 108

  Fly   522 T----LHVLCLDDLNGTTQAQLLRELRQLSQLKRQEHLLDFYGVSASPDWFYLIFEQQRMSLKR- 581
            .    :.||.....|...:..|..||..|..:.|..::|...|.: ||.:...:...:.:.|..
Worm   109 NSNKLVDVLVKRPKNHIEKEMLENELTILRLIGRHPNVLALIGYT-SPMFGRTVVVYESVELGNL 172

  Fly   582 ----KLVESR---LMAPSPRLTSLSEQLVL---QWIYELASAMNYLSSCQVVHRQLCSHSVFVTS 636
                |:.::.   :..|....:.|.|..|.   .:.:::|:.|.||:...|:||.|...::|:..
Worm   173 QHVLKITKNNFELVGVPETEFSGLDEFCVSDLHSFAFQIANGMEYLTHIPVIHRFLALRNIFLKR 237

  Fly   637 DFKLKLSVFGPLPYMNIAR-----QQPDHNRWLAPEVLRHQHHHSTRSDVWSLACVAWECCALGG 696
            :..::::.||....:|..|     ..|....|:|||.. ::...:.::||||.....:|..:||.
Worm   238 NKTIRIANFGLSKNVNDYRIIDSMDTPVPLYWMAPESY-NELIFNEKTDVWSFGVCLYELYSLGE 301

  Fly   697 TPYANAVASNQQLLEAIRAAVRPAQPAYVYG-DLYQLLLNCWQLEPSERSSCEDVA 751
            .||.|.......|:|.:....|.::|.|:.. :::..:..||..:|..|....|.|
Worm   302 DPYENVKTLFDHLMEYLEKGNRLSKPKYIDSPEIFDFMKICWNFKPETRPCFSDCA 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wsck	NP_733018.1	WSC	42..115	CDD:280068
		fn3	130..222	CDD:278470
		TyrKc	493..746	CDD:197581	62/273 (23%)
		PTKc	497..750	CDD:270623	62/273 (23%)
R09D1.13	NP_496022.1	STYKc	80..360	CDD:214568	65/301 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3801
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810