Protein Alignment Wsck and Wsck

DIOPT Version :10

• Sequence 1: NP_733018.1
• Gene: Wsck / 318600
• FlyBaseID: FBgn0046685
• Length: 791
• Species: Drosophila melanogaster
• Sequence 2: XP_308798.5
• Gene: Wsck / 1270126
• VectorBaseID: AGAMI1_014555
• Length: 769
• Species: Anopheles gambiae
• Alignment Length: 806
• Identity: 284/806 - (35%)
• Similarity: 444/806 - (55%)
• Gaps: 81/806 - (10%)

  Fly     9 HRPIPIW--LSSC---LVAMCLGLPLGAAVPQEAPAYYYVGCYT----ARTDLLHESVYAKTPQT 64
            ||    |  ||.|   |:::|.|| .||    |..||:  |||.    ||..|..|.:     ..
Mosquito    18 HR----WQSLSLCVLTLLSICGGL-AGA----EKRAYF--GCYERDRFARLALTTEHL-----DE 66

  Fly    65 CIEICEHQGHHYAVLASEKCFCANVLEPQEQQDEQLCNTRCLANKAQYCGGVGVHSYYSTILTKQ 129
            |::.|.:..|.||.|:..:|.|.|.::.:..:|.: |:.:|.......||||...:.|.|.:...
Mosquito    67 CVDSCANSFHRYAELSGSRCSCTNTIQTRIVEDRE-CDLKCGKQPDANCGGVNAQAVYETGIDVA 130

  Fly   130 PGPHHLRI-SNKTENSLTLSWNAYEARKLLLAGGAEAVLP---NQLLDNFLIKAQVLKTYSSLPA 190
            ....:||| ..:.|:::.:.|:                ||   ..:::.|.|.|:..:||:|...
Mosquito   131 GPVRNLRIEGEQKEDTIAIRWD----------------LPADDGVMVEEFEIVAEATRTYASFRI 179

  Fly   191 FPQPEFMVQSTETQFELTDLHPATLYNISVRAMCKDAQVGQSECGQASIEATTEVGLPSPVPAQP 255
            :| ..:.|.:|.|.|||::|.|.|.|||:|.::.     .:...|:|||..:||:|.|.|.|.:|
Mosquito   180 YP-VRWSVHNTSTGFELSNLQPGTDYNITVVSVS-----ARGAGGRASIAGSTEIGHPDPEPEEP 238

  Fly   256 KILSRTDRTVTIELSPIRNDNGPLSKLLVIVEYVDNALSQPFDAQLLGSWQQAQQDGVPYYIAAE 320
            .||.|.:.|:.|::....|||||::...|:|.||::.|.|..|...||::||::::.||||||||
Mosquito   239 IILRRFESTILIQIPRAVNDNGPVNYYRVVVHYVNSELIQQIDESQLGTFQQSKENKVPYYIAAE 303

  Fly   321 LDYDRPEDNRTRRFVVGDGKRYGRFTNKPLDQPDAHVHISLGLVSTLEGVTKTMYSRGTHDQHVT 385
            |:.   :|:.:.:|.||||:.|..:.|.|: ....|||||:|:||.|..|.|..|:..||:||
Mosquito   304 LEM---KDDESLQFTVGDGREYRSYFNPPI-TARTHVHISIGVVSILNHVVKVRYATTTHEQH-- 362

  Fly   386 SLDDFSYAT-----FEKGQSSVVALAVTCVIFGSCLLLSLIAYFYLRYKTCRGRRLTGGNTHEMT 445
            ...|..:..     .|:.::.:..|...|::||..|..::|.|.||.:||........|:.||:|
Mosquito   363 QYPDHHHVNLKTVEIERNETLIAILTTACILFGVVLTGAIILYVYLHFKTPAANTRPFGDHHELT 427

  Fly   446 LQTPIIERENNGYLVEDDPLPHSPENFKQQLQQLVEGYERIPRNA---LRLNVNDVIGDGRFGEI 507
            ||.||:|.|||||:    |..:....|:.:|:.::||.|....:|   |.|::|.|:|.|::|::
Mosquito   428 LQGPILEVENNGYM----PDIYEQRGFEAELRDIIEGLEPAKNHARKYLSLDINRVLGSGKYGDV 488

  Fly   508 ITGKVSTN---DFARDCTLHVLCLDDLNGTTQAQLLRELRQLSQLKRQEHLLDFYGVSASPDWFY 569
            :.|.:..:   |......:||: .||:....|...|.|.|:|:.|:...:::.||||..:|||.|
Mosquito   489 LLGALQLSQEQDGDMPAQVHVI-TDDMESVDQIAFLNEFRRLTALEGHANVILFYGVCVTPDWCY 552

  Fly   570 LIFEQQRMSLKRKLVESRL--MAPSPRLTSLSEQLVLQWIYELASAMNYLSSCQVVHRQLCSHSV 632
            |:|||.:.:||:.|:.:|:  .|.|.:.:::||::|:..:..:...|.:|:...||.::||:.:|
Mosquito   553 LLFEQMQTTLKQTLLNARVPASANSVKFSTISEEIVVNILCLVCDGMQFLADSNVVSKKLCARTV 617

  Fly   633 FVTSDFKLKLSVFGPLPYMNIARQQPDHNRWLAPEVLRHQHHHSTRSDVWSLACVAWECCALGGT 697
            :|.:.|::|:|.|||.............:||.||||::.| :|||:|||||...:.||||.||.|
Mosquito   618 YVNTKFEVKVSAFGPPLNAEDTGSPIAISRWHAPEVIKFQ-NHSTKSDVWSFGLLIWECCCLGAT 681

  Fly   698 PYANAVASNQQLLEAIRAAVRPAQPAYVYGDLYQLLLNCWQLEPSERSSCEDVAFGVRQLMTSPR 762
            ||......|  |..||||..:|.:|:::|.|||||.||||.|:.|:|.|.:|:...:||.:...|
Mosquito   682 PYGTTTTDN--LFAAIRAGQKPERPSFMYEDLYQLCLNCWDLDASDRPSFDDLRRYLRQTLPMLR 744

  Fly   763 HALSFDRVAGGLDTLPPYLPQLEAVA 788
            :.|||:|...  ..||||||.|||.:
Mosquito   745 YLLSFERKQN--VQLPPYLPHLEAAS 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wsck	NP_733018.1	WSC	42..115	CDD:460348	20/76 (26%)
		fn3	130..222	CDD:394996	27/95 (28%)
		PTKc	497..750	CDD:270623	97/257 (38%)
Wsck	XP_308798.5	None