DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wsck and styk1a

DIOPT Version :9

Sequence 1:	NP_733018.1	Gene:	Wsck / 318600	FlyBaseID:	FBgn0046685	Length:	791	Species:	Drosophila melanogaster
Sequence 2:	XP_005159545.1	Gene:	styk1a / 101886109	ZFINID:	ZDB-GENE-060503-428	Length:	435	Species:	Danio rerio

Alignment Length:	413	Identity:	97/413 - (23%)
Similarity:	159/413 - (38%)	Gaps:	84/413 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   403 VALAVTCVIFGSCLLLSLIAYFYLR------YKTCRGRRLTGGNTHEMTLQTPIIERENNGYL-- 459
            |.|.|..|:|....|..:|....|:      |:....|:......|....|..  .|.|..:|
Zfish    24 VELIVVPVLFLLLFLAIMIILLVLKCSHKKSYRHKHHRKENDHTQHHHNTQGS--HRSNRRHLQG 86

  Fly   460 ----VEDDPL-----------PHSPENFKQQLQQLVEGYERIPRNALRLNVNDVIGDGRFGEIIT 509
                .|.:|:           ||..::....:.|  :..||.|.:...|:...          |:
Zfish    87 IDAPAELNPMEHEVIPMTAQAPHEVQSSASAIPQ--QTTERHPSSFQLLSPLP----------IS 139

  Fly   510 GKVSTNDFARDCTLHVLCLDDLNGTTQAQLLRELRQ----------------LSQLKRQEHLLDF 558
            ..|..::|    |||...:|     .|..:||.|::                ||:|...|.|...
Zfish   140 FSVKQDNF----TLHRAAID-----RQPVILRVLKESANARERQSFLGFSHFLSELGPHESLPKL 195

  Fly   559 YG-VSASPDWFYLIFEQQRMSLKRKLVESR-----LMAPSPRLTSLSEQLVLQWIYELASAMNYL 617
            .| |||.......:.|.:...|...|...|     ..||    ..::|:.:.....::|||:.||
Zfish   196 LGVVSARTPLMMAVEELEHRDLLGFLWRCRQDHTGQAAP----CDMTERRIFTMGAQIASALEYL 256

  Fly   618 SSCQVVHRQLCSHSVFVTSDFKLKLSVFGPLPY--MNIAR----QQPDHNRWLAPEVLRHQHHHS 676
            .|...:|..:.:.||.|..|..:||...||..:  .|.:.    ::.:..:|.|||:|..|....
Zfish   257 HSKNCIHGNVKARSVLVGQDLSVKLWGLGPAYHRKSNASSIEDLEEIETRKWQAPELLARQPLQQ 321

  Fly   677 TRSDVWSLACVAWECCALGGTPYANAVASNQQLLEAIRAAVRPAQPAYVYGDLYQLLLNCWQLEP 741
            : |||||...:.:|...||..|:.|.:||  :||:.::......:|......||.::.:|.:...
Zfish   322 S-SDVWSFGILLYEMVTLGEAPFPNIMAS--ELLQHLQRENTLKRPPNCSNTLYSIMKSCCKWRA 383

  Fly   742 SERSSCEDVAFGVRQLMTSPRHA 764
            .:|.|..::   :|:|.:..|.|
Zfish   384 KDRVSLAEL---IRKLQSGERSA 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wsck	NP_733018.1	WSC	42..115	CDD:280068
		fn3	130..222	CDD:278470
		TyrKc	493..746	CDD:197581	69/280 (25%)
		PTKc	497..750	CDD:270623	69/280 (25%)
styk1a	XP_005159545.1	PKc_like	158..397	CDD:304357	62/248 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900