DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31111 and Tbrg1

DIOPT Version :9

Sequence 1:	NP_733074.1	Gene:	CG31111 / 318595	FlyBaseID:	FBgn0051111	Length:	269	Species:	Drosophila melanogaster
Sequence 2:	NP_001009344.2	Gene:	Tbrg1 / 300521	RGDID:	1305123	Length:	406	Species:	Rattus norvegicus

Alignment Length:	314	Identity:	95/314 - (30%)
Similarity:	148/314 - (47%)	Gaps:	55/314 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NLKYKRRYESLKRSVKSYLLENAALTDEICRLQAELSVTRSQRLYLIERLMFHEGLEK------- 59
            |.||:.:|..|:|:.|:.:.||||:.|||.||:.:....:.:|.||:::|:....|.:
  Rat    30 NEKYRLKYLRLRRAAKATVFENAAVCDEIARLEEKFLKAKEERRYLLKKLLQIHALTEGEPQAAA 94

  Fly    60 -SNSGRPSVSNGKNDAAETTKKYSPVVSHKNPVEDKPK----------------NVTIVRKK--- 104
             |:|....::.|...:..|.:...|....:.|...|.|                ..|..|||
  Rat    95 PSHSSSLPLAYGVTSSVGTIQGAGPSTGAEEPFAKKSKKEKKEKGKENSKLEVLKKTSKRKKMEG 159

  Fly   105 ---------------KPMFPMNLNNVLLHSLGEIISVNPNFHTESWIYPVGYVATRIYAHPKDPR 154
                           :|:||:.|..:.::||||||:..|.||.|:.||||||.:||:||..|.|.
  Rat   160 GARKLVRPIALDPSGQPVFPIGLGGLTVYSLGEIITNRPGFHDENAIYPVGYCSTRVYASMKCPD 224

  Fly   155 KKCVFTCKILNNAGIPQFQIIPDNDLDGVFFGESANMCHMELLNSIQRSPCVKIKIPFDVQGEVF 219
            :||::||:|.:....|||:|:|::|......|.||:.|:.|||.:|..:....:..|... |..|
  Rat   225 QKCLYTCQIKDGGVQPQFEIVPEDDPRNTIVGSSADACYEELLRAISAATGKLMPNPLSC-GADF 288

  Fly   220 FGLSNQKTQSLLMMDPAFHQCTNF-----------KGFAVQNVQSLNSASLSFE 262
            ||.|:....:|:...|....|.|:           ||...|.:.. |.|::|.|
  Rat   289 FGFSHPTIHNLIQSCPEAQNCVNYQWVKFDACKPRKGQLSQELPE-NDAAMSLE 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31111	NP_733074.1	FYRN	114..163	CDD:283589	26/48 (54%)
CG31111	NP_733074.1	FYRC	171..246	CDD:197781	24/85 (28%)
Tbrg1	NP_001009344.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..144		4/27 (15%)
		FYRN	183..233	CDD:399155	26/49 (53%)
		FYRC	239..320	CDD:399156	24/81 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342662
Domainoid	1	1.000	63	1.000	Domainoid score	I10005
eggNOG	1	0.900	-	-		E2759_KOG4443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H18102
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4423
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1397649at2759
OrthoFinder	1	1.000	-	-		FOG0005809
OrthoInspector	1	1.000	-	-		otm44541
orthoMCL	1	0.900	-	-		OOG6_105977
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4784
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.660